Sileny Han
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View article: TUSC3 serves as a rate-limiting gatekeeper of a glycan-mediated ER Triage Checkpoint for BMP4/Dpp
TUSC3 serves as a rate-limiting gatekeeper of a glycan-mediated ER Triage Checkpoint for BMP4/Dpp Open
SUMMARY Trimming of the three glucose residues decorating nascent N -glycoproteins is a critical step for their entry into the endoplasmic reticulum quality control (ERQC) cycle and recognition by ER chaperones. However, the functional rel…
View article: Acupuncture as an alternative treatment for polycystic ovary syndrome: Effects on ovulation rate, pregnancy rate and endometrial receptivity
Acupuncture as an alternative treatment for polycystic ovary syndrome: Effects on ovulation rate, pregnancy rate and endometrial receptivity Open
View article: Breastfeeding after breast cancer in young <i>BRCA</i> carriers
Breastfeeding after breast cancer in young <i>BRCA</i> carriers Open
Background We investigated safety of breastfeeding after breast cancer in patients carrying germline BRCA pathogenic or likely pathogenic variants. Methods This was an international, multicenter, hospital-based, retrospective cohort study …
View article: SEXUAL WELL-BEING AND ITS ASSOCIATION WITH BREAST SURGERY INDICATIONS: AN EXPLORATORY STUDY
SEXUAL WELL-BEING AND ITS ASSOCIATION WITH BREAST SURGERY INDICATIONS: AN EXPLORATORY STUDY Open
Objectives Breast surgery can have a negative impact on a woman’s body image. The impact of breast cancer (BC) surgery on sexuality and body image is well described. This study investigates if surgery has impact on sexual wellbeing and/or …
View article: WHAT IS THE IMPACT OF IATROGENIC MENOPAUSE ON VAGINAL HEALTH AND SEXUALITY? (PRELIMINARY) RESULTS OF “VOLUPTA”; THE MENOPAUSE MICROBIOME STUDY
WHAT IS THE IMPACT OF IATROGENIC MENOPAUSE ON VAGINAL HEALTH AND SEXUALITY? (PRELIMINARY) RESULTS OF “VOLUPTA”; THE MENOPAUSE MICROBIOME STUDY Open
Objectives Genitourinary symptoms of menopause (GSM) are common in women with a history of breast cancer (BC). When GSM occurs these symptoms are likely to be moderate to severe. Little is known about the timing of onset of vaginal changes…
View article: 458P What is the impact of iatrogenic menopause on vaginal health and microbiome dynamics? Preliminary results of the menopause microbiome study
458P What is the impact of iatrogenic menopause on vaginal health and microbiome dynamics? Preliminary results of the menopause microbiome study Open
View article: Sexuality after breast cancer treatment: An experience of asymmetry
Sexuality after breast cancer treatment: An experience of asymmetry Open
Background: Breast cancer survivorship is often associated with a negative impact on sexual function and sexual well-being. Given that sexual well-being contributes to quality of life—including for breast cancer survivors—it is important t…
View article: Assisted Reproductive Technology in Young Brca Carriers with a Pregnancy after Breast Cancer: An International Cohort Study
Assisted Reproductive Technology in Young Brca Carriers with a Pregnancy after Breast Cancer: An International Cohort Study Open
View article: Supplementary Tables 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Supplementary Tables 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Table S1 - Table S4
View article: Supplementary Figures 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Supplementary Figures 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Supplmeentary Figures S1-S28
View article: Supplementary Tables 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Supplementary Tables 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Table S1 - Table S4
View article: Data from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Data from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Purpose: Postpartum breast cancer patients diagnosed after cessation of breastfeeding (post-weaning, PP-BCPW), have a particularly poor prognosis compared to patients diagnosed during lactation (PP-BCDL), or to pregna…
View article: Supplementary Figures 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Supplementary Figures 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Supplmeentary Figures S1-S28
View article: Breast cancer incidence, stage distribution, and treatment shifts during the 2020 COVID-19 pandemic: a nationwide population-level study
Breast cancer incidence, stage distribution, and treatment shifts during the 2020 COVID-19 pandemic: a nationwide population-level study Open
View article: Abstract PO3-05-05: The effect of histological breast cancer subtype on progression free survival in patients with CDK4/6 inhibitors
Abstract PO3-05-05: The effect of histological breast cancer subtype on progression free survival in patients with CDK4/6 inhibitors Open
Background: Multiple trials have proven that adding CDK4/6 inhibitors to endocrine treatment increases progression free (PFS) and overall survival (OS) of patients with metastatic estrogen receptor (ER)-positive HER2 negative breast cancer…
View article: 98P The added value of whole-body diffusion weighted MRI (WB-DWI/MRI) in staging invasive lobular carcinoma
98P The added value of whole-body diffusion weighted MRI (WB-DWI/MRI) in staging invasive lobular carcinoma Open
Invasive Lobular Carcinoma (ILC) challenges standard-of-care imaging, with disease spread being underestimated and missed in many patients. WB-DWI/MRI has demonstrated its added value in detecting lymph node, peritoneal and bone metastases…
View article: Breast cancer risk factors and survival by tumor subtype: Pooled analyses from the breast cancer association consortium
Breast cancer risk factors and survival by tumor subtype: Pooled analyses from the breast cancer association consortium Open
Background: It is not known whether modifiable lifestyle factors that predict survival after invasive breast cancer differ by subtype. Methods: We analyzed data for 121,435 women diagnosed with breast cancer from 67 studies in the Breast C…
View article: Health-related quality of life in patients with newly diagnosed advanced ovarian cancer treated with niraparib vs placebo: Results from the phase 3 randomized PRIMA/ENGOT-OV26/GOG-3012 trial
Health-related quality of life in patients with newly diagnosed advanced ovarian cancer treated with niraparib vs placebo: Results from the phase 3 randomized PRIMA/ENGOT-OV26/GOG-3012 trial Open
View article: Pregnancy After Breast Cancer in Young <i>BRCA </i>Carriers
Pregnancy After Breast Cancer in Young <i>BRCA </i>Carriers Open
Importance Young women with breast cancer who have germline pathogenic variants in BRCA1 or BRCA2 face unique challenges regarding fertility. Previous studies demonstrating the feasibility and safety of pregnancy in breast cancer survivors…
View article: A randomized phase 2 study of sapanisertib in combination with paclitaxel versus paclitaxel alone in women with advanced, recurrent, or persistent endometrial cancer
A randomized phase 2 study of sapanisertib in combination with paclitaxel versus paclitaxel alone in women with advanced, recurrent, or persistent endometrial cancer Open
View article: European multidisciplinary tumor boards support cross-border networking and increase treatment options for patients with rare gynecological tumors
European multidisciplinary tumor boards support cross-border networking and increase treatment options for patients with rare gynecological tumors Open
View article: Navigating next-generation HR+/HER2− metastatic breast cancer therapies: a critical commentary on abemaciclib vs. tucidinostat after palbociclib progression
Navigating next-generation HR+/HER2− metastatic breast cancer therapies: a critical commentary on abemaciclib vs. tucidinostat after palbociclib progression Open
View article: Supplementary Figures 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Supplementary Figures 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Supplmeentary Figures S1-S28
View article: Supplementary Figures 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Supplementary Figures 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Supplmeentary Figures S1-S28
View article: Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Table S1 - Table S4
View article: Data from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Data from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Purpose:Patients with postpartum breast cancer diagnosed after cessation of breastfeeding (postweaning, PP-BCPW) have a particularly poor prognosis compared with patients diagnosed during lactation (PP-BCDL), or to pr…
View article: Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Table S1 - Table S4
View article: Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Table S1 - Table S4
View article: Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Table S1 - Table S4
View article: Supplementary Figures 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Supplementary Figures 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Supplmeentary Figures S1-S28