Shao Zhong
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View article: SGLT2 Inhibitors Confer Cardiovascular Protection via the Gut-Kidney-Heart Axis: Mechanisms and Translational Perspectives
SGLT2 Inhibitors Confer Cardiovascular Protection via the Gut-Kidney-Heart Axis: Mechanisms and Translational Perspectives Open
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have demonstrated significant cardiovascular and renal benefits beyond glycemic control, yet their integrated mechanisms remain incompletely understood. Emerging evidence highlights the gu…
View article: Trend and burden of Alzheimer's disease and other dementias in China 1990–2021: a systematic analysis with forecasts to 2035
Trend and burden of Alzheimer's disease and other dementias in China 1990–2021: a systematic analysis with forecasts to 2035 Open
Background: Alzheimer's Disease (AD) has become a major public health problem affecting the health of the elderly as the global population ages. This study aims to analyze the epidemiological characteristics of AD in China, predict its fu…
View article: Effects of Cognitive Behavioral Therapy for Diet on Postprandial Glucose and Pregnancy Outcomes in Gestational Diabetes Mellitus: Multicenter Randomized Controlled Trial
Effects of Cognitive Behavioral Therapy for Diet on Postprandial Glucose and Pregnancy Outcomes in Gestational Diabetes Mellitus: Multicenter Randomized Controlled Trial Open
Background Gestational diabetes mellitus (GDM) is associated with an elevated risk of adverse maternal and neonatal outcomes. Dietary management is a cornerstone of GDM treatment due to its beneficial effects on metabolic control. However,…
View article: Association of Systemic Immune-Inflammatory Index with Risk of Foot Ulcer Amputation in Patients with Type 2 Diabetes Mellitus: Insights from a Cross-Sectional Study
Association of Systemic Immune-Inflammatory Index with Risk of Foot Ulcer Amputation in Patients with Type 2 Diabetes Mellitus: Insights from a Cross-Sectional Study Open
Higher SII levels in patients with type 2 DFU raise the risk of amputation. For assessing the risk of amputation in patients with DFUs, SII is likely to be a valuable biomarker for DFU amputation.
View article: Specific modes of exercise to improve rotator cuff-related shoulder pain: systematic review and meta-analysis
Specific modes of exercise to improve rotator cuff-related shoulder pain: systematic review and meta-analysis Open
Objective To investigate the effect of specific modes of exercise on rotator cuff-related shoulder pain (RCRSP) patients, aiming to provide a theoretical reference for conservative treatment and exercise prescription. Methods Data sources …
View article: A novel radio resource allocation scheme for beam-hopping 6G satellite internet network based on graph mapping and generative adversarial network
A novel radio resource allocation scheme for beam-hopping 6G satellite internet network based on graph mapping and generative adversarial network Open
In this letter, we are the first to focus on the issue of reliable and flexible radio resource allocation (RRA) for beam-hopping (BH) in satellite internet network (SIN). The main new challenges are accurate and dynamic radio resource mode…
View article: Association between cardiometabolic index and kidney stone from NHANES: a population-based study
Association between cardiometabolic index and kidney stone from NHANES: a population-based study Open
Purpose The Cardiometabolic Index (CMI) is a novel marker of visceral obesity and dyslipidemia. Our study aimed to explore the association between CMI and kidney stones among US adults. Methods This cross-sectional study was conducted amon…
View article: Genetic Associations of Lipids and Lipid-Modifying Drug Targets With Type 2 Diabetes in the Chinese Population
Genetic Associations of Lipids and Lipid-Modifying Drug Targets With Type 2 Diabetes in the Chinese Population Open
Our findings suggested potential adverse effects of lower LDL-C, TG levels, as well as long-term use of APOC3 inhibitors on T2D risk in Chinese populations. These findings highlight the need for cautious lipid management strategies in T2D …
View article: Glycemic Variability in Pancreatogenic Diabetes Mellitus: characteristics, Risks, Potential Mechanisms, and Treatment Possibilities
Glycemic Variability in Pancreatogenic Diabetes Mellitus: characteristics, Risks, Potential Mechanisms, and Treatment Possibilities Open
In recent years, pancreatogenic diabetes mellitus has garnered significant attention due to its high incidence, complications, and mortality rates. Glycemic variability (GV) can increase the risk of pancreatogenic diabetes mellitus and its…
View article: Role of Triglyceride-Glucose Index in Type 2 Diabetes Mellitus and Its Complications
Role of Triglyceride-Glucose Index in Type 2 Diabetes Mellitus and Its Complications Open
Insulin resistance (IR) is the major mechanism in the pathogenesis of type 2 diabetes mellitus (T2DM). Early identification of IR is of great significance for preventing the onset of T2DM and delaying the progression of the disease. Previo…
View article: Association between the atherogenic index of plasma and kidney stones: a nationally representative study
Association between the atherogenic index of plasma and kidney stones: a nationally representative study Open
The AIP index may be a potential epidemiological tool to quantify the role of dyslipidemia in the risk of kidney stones in US adults.
View article: Generalization of a Deep Learning Model for Continuous Glucose Monitoring–Based Hypoglycemia Prediction: Algorithm Development and Validation Study
Generalization of a Deep Learning Model for Continuous Glucose Monitoring–Based Hypoglycemia Prediction: Algorithm Development and Validation Study Open
Background Predicting hypoglycemia while maintaining a low false alarm rate is a challenge for the wide adoption of continuous glucose monitoring (CGM) devices in diabetes management. One small study suggested that a deep learning model ba…
View article: Correlation Between Blood Urea Nitrogen and Short- and Long-Term Glycemic Variability in Elderly Patients with Type 2 Diabetes Mellitus Who Were hospitalized:A Retrospective Study
Correlation Between Blood Urea Nitrogen and Short- and Long-Term Glycemic Variability in Elderly Patients with Type 2 Diabetes Mellitus Who Were hospitalized:A Retrospective Study Open
In elderly patients with T2DM were hospitalized, BUN levels were positively associated with GV.Therefore, monitoring BUN levels were beneficial in assessing the degree of GV.
View article: The relationship between weight-adjusted-waist index and diabetic kidney disease in patients with type 2 diabetes mellitus
The relationship between weight-adjusted-waist index and diabetic kidney disease in patients with type 2 diabetes mellitus Open
Purpose Obesity, particularly abdominal obesity, is seen as a risk factor for diabetic complications. The weight-adjusted-waist index (WWI) is a recently developed index for measuring adiposity. Our goal was to uncover the potential correl…
View article: Identification of Senescence‐Associated Biomarkers in Diabetic Glomerulopathy Using Integrated Bioinformatics Analysis
Identification of Senescence‐Associated Biomarkers in Diabetic Glomerulopathy Using Integrated Bioinformatics Analysis Open
Background . Cellular senescence is thought to play a significant role in the onset and development of diabetic nephropathy. The goal of this study was to explore potential biomarkers associated with diabetic glomerulopathy from the perspe…
View article: Causality of Blood Metabolites on Proliferative Diabetic Retinopathy: Insights From a Genetic Perspective
Causality of Blood Metabolites on Proliferative Diabetic Retinopathy: Insights From a Genetic Perspective Open
Background: Our goal was to examine the causal link between blood metabolites, their ratios, and the risk of developing proliferative diabetic retinopathy (PDR) from a genetic insight. Methods: Summary‐level data about 1400 blood metabolit…
View article: Co-treatment of Astragaloside IV with Vitamin D in Diabetic PeripheralNeuropathic Rats: Protective Effects and Potential Mechanisms
Co-treatment of Astragaloside IV with Vitamin D in Diabetic PeripheralNeuropathic Rats: Protective Effects and Potential Mechanisms Open
Objective: The potential mechanism underlying the protective effect of Astragaloside IV (AS-IV) co-treatment with 1, 25-dihydroxy-vitamin D (Vit-D) on neuropathy in diabetic high-fat rats was investigated Methods: The rat diabetic hyperlip…
View article: The relationship between triglyceride-glucose index and albuminuria in United States adults
The relationship between triglyceride-glucose index and albuminuria in United States adults Open
Purpose Triglyceride-glucose (TyG) index is a simple and reliable indicator of metabolic dysfunction. We aimed to investigate a possible relationship between TyG index and albuminuria in the United States adult population. Methods This cro…
View article: Correlation Between Glycemic Variability and Diabetic Complications: A Narrative Review
Correlation Between Glycemic Variability and Diabetic Complications: A Narrative Review Open
Diabetes mellitus is a metabolic disorder with a complex etiology in which glycemic dynamics are disturbed and the body is unable to maintain the process of glucose homeostasis through the pancreas. Persistent symptoms of high blood glucos…
View article: Impact of Visit-to-Visit Triglyceride-Glucose Index Variability on the Risk of Cardiovascular Disease in the Elderly
Impact of Visit-to-Visit Triglyceride-Glucose Index Variability on the Risk of Cardiovascular Disease in the Elderly Open
Background. The aging population is increasingly susceptible to cardiovascular disease (CVD). Visit-to-visit variability in glucose and lipid levels both contributed to CVD risk independent of their mean values. However, whether variabilit…