Explanipedia

A non-destructive detection method for crab roe within live Chinese mitten crabs (Eriocheir sinensis) via near-infrared transmittance spectroscopy Open

Mengyao Lu, Chi Zhang, Shuwen Jiang, Yi Jiao, Xiaohe Gu , et al. · 2025

Association between fibrinogen-to-albumin ratio and all-cause mortality in critically ill patients with atrial fibrillation: a retrospective study using the MIMIC-IV database Open

Yuchen Han, Shuwen Jiang, Siyuan Cheng, Lishuai Zhang · 2025

FAR could be used as a useful tool for evaluating illness severity and informing clinical management in AF patients admitted to the ICU.

Preparation and High-Temperature Strain Response of Fecral/Pdcr Composite Thin-Film Strain Gauge Open

Shiwei Zhou, Zhifeng Zhou, Shuwen Jiang, Bowan Tao, Wanli Zhang · 2025

PPARα agonist ameliorates cholestatic liver injury by regulating hepatic macrophage homeostasis Open

Qingmiao Shi, Xue Chen, Yifan Zeng, Qingfei Chu, Shuwen Jiang , et al. · 2024

Inflammatory response plays an essential role in the pathogenesis of cholestatic liver injury. PPARα agonists have been shown to regulate bile acid homeostasis and hepatic inflammation. However, the immunoregulatory mechanisms through whic…

A Notch signaling pathway-related gene signature: Characterizing the immune microenvironment and predicting prognosis in hepatocellular carcinoma Open

Qingmiao Shi, Shuwen Jiang, Yifan Zeng, Xin Yuan, Yaqi Zhang , et al. · 2024

Background and Objectives Prior studies have highlighted an escalating global burden of hepatocellular carcinoma (HCC). The Notch signaling pathway regulates the initiation and development of HCC and determines the HCC prognosis. Methods T…

Preclinical pharmacokinetic characterization of amdizalisib, a novel PI3Kδ inhibitor for the treatment of hematological malignancies Open

Shuwen Jiang, Xiangkun Li, Weifang Xue, Sumei Xia, Jian Wang , et al. · 2024

Amdizalisib, also named HMPL-689, a novel selective and potent PI3Kδ inhibitor, is currently under Phase II clinical development in China for treating hematological malignancies. The preclinical pharmacokinetics (PK) of amdizalisib were ex…

Notch signaling pathway in cancer: from mechanistic insights to targeted therapies Open

Qingmiao Shi, Chen Xue, Yifan Zeng, Xin Yuan, Qingfei Chu , et al. · 2024

Clinical Significance of a Novel Vasculogenic Mimicry-based Prognostic Model in Hepatocellular Carcinoma Open

Yifan Zeng, Shuwen Jiang, Zhuoqi Lou, Lin Chen, Yongtao Zhang , et al. · 2024

Background: Vasculogenic mimicry, a novel neovascularization pattern of aggressive tumors, is associated with poor clinical outcomes. Objective: The aim of this research was to establish a new model, termed VC score, to predict the prognos…

Clinical significance of RNA methylation in hepatocellular carcinoma Open

Qiongling Bao, Yifan Zeng, Qizhuo Lou, Xuewen Feng, Shuwen Jiang , et al. · 2024

Hepatocellular carcinoma (HCC) is a primary liver malignancy with high mortality rates and poor prognosis. Recent advances in high-throughput sequencing and bioinformatic technologies have greatly enhanced the understanding of the genetic …

Prognostic and immune predictive roles of a novel tricarboxylic acid cycle-based model in hepatocellular carcinoma Open

Yifan Zeng, Tao Yu, Shuwen Jiang, Jinzhi Wang, Lin Chen , et al. · 2024

Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer. Since the tricarboxylic acid cycle is widely involved in tumor metabolic reprogramming and cuproptosis, investigating related genes may help to identify prognostic …

The Responses of Ozone to the Solar Eclipse on the 21st of June 2020 in the Mesosphere and Upper Stratosphere Open

Jingyuan Li, Shuwen Jiang, Jingrui Yao, Jingqi Cui, J. Y. Lu , et al. · 2023

Microwave Limb Sounder (MLS) observations showed an obvious variation of ozone concentration during the annular solar eclipse on 21 June 2020 in the mesosphere and upper stratosphere. Ozone concentration slightly reduced near 40 km in the …

Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1 Open

Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka , et al. · 2023

Adenosine monophosphate–activated protein kinase (AMPK) activity is stimulated to promote metabolic adaptation upon energy stress. However, sustained metabolic stress may cause cell death. The mechanisms by which AMPK dictates cell death a…

Epitaxial growth of (Ba0.7Sr0.3)TiO3 thin films on GdScO3 substrates by magnetron sputtering Open

Dongjin Ye, Penghao Nie, Shuwen Jiang, Wanli Zhang · 2023

Epitaxial growth of Ba0.7Sr0.3TiO3 (BST70) thin films on GdScO3 (GSO) substrates had been realized using the radio frequency magnetron sputtering system with the epitaxial alignment [001]BST70||[110]GSO and [010]BST70||[001]GSO. Reciprocal…

The Northern and Southern Hemispheric Asymmetries of Mesospheric Ozone at High Latitudes During the January 2012 Solar Proton Events Open

Shiping Xiong, Jingyuan Li, Guanchun Wei, J. Y. Lu, Yufeng Tian , et al. · 2023

Observations by the Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) and simulations by the Whole Atmosphere Community Climate Model‐eXtended (WACCM‐X) are used to analyze the impacts of the January 2012 solar proton …

Change Profiles and Functional Targets of MicroRNAs in Type 2 Diabetes Mellitus Patients with Obesity Open

Guanhua Lu, Huanhuan Gao, Zhiyong Dong, Shuwen Jiang, Ruixiang Hu , et al. · 2023

Background: MicroRNAs (miRNAs) exert an essential contribution to obesity and type 2 diabetes mellitus (T2DM). This study aimed to investigate the differences of miRNAs in the presence and absence of T2DM in patients with obesity, as well …

Intelligent Grading of Tobacco Leaves Using an Improved Bilinear Convolutional Neural Network Open

Mengyao Lu, Cong Wang, Wenbiao Wu, Dinglian Zhu, Qiang Zhou , et al. · 2023

At present, tobacco leaf grading relies mainly on manual classification, which is highly intensive with respect to labor, materials, and cost; in addition, the performance of manual grading is poor. The realization of automatic grading is …

Effects of the annular eclipse on the surface O3 in yunnan province, China Open

Yufeng Tian, Jingyuan Li, Chaolei Yang, Jingqi Cui, Fuzhen Shen , et al. · 2022

The impact of the annual solar eclipse, starting on 21st June 2020, attributable to surface ozone concentration (O 3 ) has been investigated in this study. To estimate the influence of the solar eclipse on O 3 better, the variations of one…

A Memristor‐Based Bioinspired Multimodal Sensory Memory System for Sensory Adaptation of Robots Open

Xinqiang Pan, Jiejun Wang, Zhen Deng, Yao Shuai, Wenbo Luo , et al. · 2022

Sensory adaptation plays a critical role in humans interacting with the environment. Inspired by humans, realization of sensory adaptation on robots can make them adapt to the environment gradually. The gradual change of sensitivity that d…

Qualitative Discrimination of Intact Tobacco Leaves Based on Near-Infrared Technology Open

Mengyao Lu, Qiang Zhou, Tianen Chen, Junhui Li, Shuwen Jiang , et al. · 2021

To explore the application of near-infrared (NIR) technology to the quality analysis of raw intact tobacco leaves, a nondestructive discrimination method based on NIR spectroscopy is proposed. A “multiregion + multipoint” NIR spectrum acqu…

Preparation of HVOF Thermal Sprayed WC-Ni-WS <sub>2</sub> Self-Lubricating Coatings Using Electroless Ni-WS <sub>2</sub> Coated Powders and Evaluation of the Tribological Properties Open

Y.J. Liu, Shuwen Jiang, Jiaming Yan, Xianglong Zhu · 2021

Optimal Model of Chicken Distribution Vehicle Scheduling Based on Order Clustering Open

Dong Chen, Tian'en Chen, Shuwen Jiang, Chi Zhang, Cong Wang , et al. · 2020

In order to solve the problems that orders are widely distributed, scheduling of distribution vehicle needs a lot of manpower,and high cost of chicken distribution in large-scale poultry enterprise, in this research, combined with the idea…

Preparation and evaluation of PdCr thin film resistive strain gauges Open

Hao Liu, Shuwen Jiang, Hongchuan Jiang, Xiaohui Zhao, Wanli Zhang · 2017

Thin film resistive strain gauges using PdCr alloy as sensing material were fabricated on nickel-based alloy substrate, and evaluated for strain response, apparent strain and drift strain over a temperature range to 800 °C. The results ind…

Microstructure Evolution and Thermoelectric Property of Pt-PtRh Thin Film Thermocouples Open

Xiaohui Zhao, Xianguai Liang, Shuwen Jiang, Wanli Zhang, Hongchuan Jiang · 2017

Due to their small size, extremely fast response, and low cost, refractory metallic thin film thermocouples (TFTCs) are well suited for the surface temperature measurement of hot components. In this study, PtRh films with different amounts…

Influence of composition on the structure and properties of SrO–Sb2O3–P2O5 low-melting sealing glasses Open

Haining Nie, Jingjing Zhang, Yajun Qi, Zhiqiang Wang, Hai Lin , et al. · 2015

SrO–Sb 2 O 3 –P 2 O 5 glass system was prepared by high temperature melting method. The effects of Sb 2 O 3 and P 2 O 5 content on the structure, thermal behavior and chemical durability of the glasses were studied by infrared spectrometer…

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