Shuting Yu
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View article: Continuous Exposure to Environmental Endocrine Disruptors on the Prognosis of Children With Nephritis: An Observational Cohort Study
Continuous Exposure to Environmental Endocrine Disruptors on the Prognosis of Children With Nephritis: An Observational Cohort Study Open
Objective Explore the impact of partial urinary environmental endocrine disruptors (EEDs) on the pathogenesis and renal function in paediatric patients diagnosed with Henoch‐Schönlein purpura nephritis (HSPN). Methods This was an observati…
View article: Iron Deficiency Drives Th2-Mediated Immunity in Pediatric Atopic Dermatitis Through DNA Hypermethylation and TIGIT Suppression in IL-10-Producing Breg Cells
Iron Deficiency Drives Th2-Mediated Immunity in Pediatric Atopic Dermatitis Through DNA Hypermethylation and TIGIT Suppression in IL-10-Producing Breg Cells Open
Iron deficiency contributes to Th2 cell expansion in pediatric AD via DNA methylation and TIGIT suppression in IL-10-producing Breg cells.
View article: circDCBLD2 regulates the Th1/Th2 immune balance via the miR-26a-5p/PTEN axis
circDCBLD2 regulates the Th1/Th2 immune balance via the miR-26a-5p/PTEN axis Open
Asthma is a prevalent chronic respiratory disease in children. Recently, adjusting the Th1/Th2 imbalance has become a significant focus in asthma immunotherapy. The present study aims to investigate the roles and mechanisms of circDCBLD2 i…
View article: Transcript isoform diversity defines molecular subtypes and prognosis in acute myeloid leukemia through long-read sequencing
Transcript isoform diversity defines molecular subtypes and prognosis in acute myeloid leukemia through long-read sequencing Open
Acute myeloid leukemia (AML) is a genetically complex and clinically heterogeneous hematopoietic malignancy. This study employs long-read transcriptome analysis using oxford nanopore technologies sequencing on 60 primary AML bone marrow sa…
View article: Forest conversion reduces soil water retention in tropical rainforest by altering soil properties
Forest conversion reduces soil water retention in tropical rainforest by altering soil properties Open
Extensive primary forests are being converted to secondary forests and plantation owing to human activities in recent decades, which has substantial effects on soil hydrological processes. However, the potential impact of forest conversion…
View article: Water use patterns of five dominant tree species in tropical secondary forests
Water use patterns of five dominant tree species in tropical secondary forests Open
Although water use strategies of tree species are critical for maintaining tropical rainforest ecosystem function, the water use pattern of dominant tree species in tropical secondary forests remain poorly understood. In this study, with s…
View article: Forest restoration in tropical forests recovers topsoil water retention but does not improve deep soil layers
Forest restoration in tropical forests recovers topsoil water retention but does not improve deep soil layers Open
Tropical primary forests have been rapidly reduced in recent decade owing to slash-and-burn, leading to the formation of tropical secondary forests in different recovery stages. However, it is still unclear whether the soil water retention…
View article: Application of sirolimus in an infant presenting with a life-threatening lymphatic malformation of the head and neck: a case report
Application of sirolimus in an infant presenting with a life-threatening lymphatic malformation of the head and neck: a case report Open
Extensive lymphatic malformations in the head and neck region pose a significant risk due to potential airway compression, and conventional treatment modalities have proven largely ineffective. Currently, systemic administration of sirolim…
View article: Geometric distribution of plaque calcification is associated with postprocedural hypotension after carotid artery stenting
Geometric distribution of plaque calcification is associated with postprocedural hypotension after carotid artery stenting Open
Background Our study aimed to investigate the relationship between the geometric distribution of plaque calcification and the occurrence of postprocedural hypotension following carotid artery stenting (CAS). Methods We retrospectively anal…
View article: Cell-Free Therapy Based on Adipose Stem Cell-Derived Exosomes to Inhibit Scar Formation Proactively: Mechanisms and Clinical Targeting Applications
Cell-Free Therapy Based on Adipose Stem Cell-Derived Exosomes to Inhibit Scar Formation Proactively: Mechanisms and Clinical Targeting Applications Open
This review provides an in-depth analysis of the potential benefits of cell-free therapy based on adipose-derived exosomes (ADSC-Exos) in inhibiting scar formation. The review highlights the advantages of using ADSC-Exos. It also explores …
View article: A phase 2 pilot study of umbilical cord blood infusion as an adjuvant consolidation therapy in elderly patients with acute myeloid leukemia
A phase 2 pilot study of umbilical cord blood infusion as an adjuvant consolidation therapy in elderly patients with acute myeloid leukemia Open
Acute myeloid leukemia (AML) is an aging-related malignancy, with patients aged ≥60 years old facing significantly poorer prognosis. Umbilical cord blood (UCB) has emerged as a promising source with effective anti-aging roles. Here, we con…
View article: Lyra: An Efficient and Speech-Centric Framework for Omni-Cognition
Lyra: An Efficient and Speech-Centric Framework for Omni-Cognition Open
As Multi-modal Large Language Models (MLLMs) evolve, expanding beyond single-domain capabilities is essential to meet the demands for more versatile and efficient AI. However, previous omni-models have insufficiently explored speech, negle…
View article: Single-cell multiomics reveals a gene regulatory circuit promoting leukemia cell differentiation
Single-cell multiomics reveals a gene regulatory circuit promoting leukemia cell differentiation Open
Cancer differentiation therapy aims to induce maturation of neoplastic cells, yet how cell fate is determined in oncogenic cellular contexts is poorly understood. Here we integrate chromatin accessibility and transcriptome analysis at sing…
View article: The Effect of Environmental Endocrine Disruptors on disease progression in children with Henoch- Schoenlein Purpura Nephritis
The Effect of Environmental Endocrine Disruptors on disease progression in children with Henoch- Schoenlein Purpura Nephritis Open
Objective To explore the cross-sectional relationship between exposure to Environmental Endocrine Disruptors (EEDs) and Henoch-Schoenlein Purpura Nephritis (HSPN) risk in Children. Methods This was a retrospective case-control study of 31 …
View article: Supplementary Table S1 from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study
Supplementary Table S1 from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study Open
Table S1. The prevalence of oral HPV infection in different age groups.
View article: Supplementary Figure S1 from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study
Supplementary Figure S1 from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study Open
Figure S1 Design and flow chart of the study. Data in this study were from the DLCC study, and the data resource, population selection, information collected and statistical methods were demonstrated in this figure. DLCC: the Diverse Life-…
View article: Supplementary Table S1 from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study
Supplementary Table S1 from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study Open
Table S1. The prevalence of oral HPV infection in different age groups.
View article: Data from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study
Data from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study Open
Background:Human papillomavirus (HPV) infection is a predominant cause of oropharyngeal squamous cell carcinoma. However, there is limited knowledge about the epidemiology of oral HPV infections among adults in China.Methods:We collected d…
View article: Data from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study
Data from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study Open
Background:Human papillomavirus (HPV) infection is a predominant cause of oropharyngeal squamous cell carcinoma. However, there is limited knowledge about the epidemiology of oral HPV infections among adults in China.Methods:We collected d…
View article: Supplementary Figure S1 from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study
Supplementary Figure S1 from Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study Open
Figure S1 Design and flow chart of the study. Data in this study were from the DLCC study, and the data resource, population selection, information collected and statistical methods were demonstrated in this figure. DLCC: the Diverse Life-…
View article: Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study
Epidemiology of Oral Human Papillomavirus Infection among Diverse Chinese Adults in Typical Areas of China: Findings from the DLCC Study Open
Background: Human papillomavirus (HPV) infection is a predominant cause of oropharyngeal squamous cell carcinoma. However, there is limited knowledge about the epidemiology of oral HPV infections among adults in China. Methods: We collecte…
View article: Intratumoral <i>Leptotrichia</i> is a novel microbial marker for favorable clinical outcomes in head and neck cancer patients
Intratumoral <i>Leptotrichia</i> is a novel microbial marker for favorable clinical outcomes in head and neck cancer patients Open
Dear editor: Head and neck squamous cell carcinoma (HNSCC) accounts for more than 70 million cancer cases annually around the world.1 The pathogenesis of HNSCC is not fully understood, but several risk factors for HNSCC, such as smoking, a…
View article: Quality of Life in Patients With Benign Lateral Skull Base Neoplasms Following Infratemporal Fossa Approaches
Quality of Life in Patients With Benign Lateral Skull Base Neoplasms Following Infratemporal Fossa Approaches Open
Objectives: Infratemporal fossa approaches (IFAs) allow the total resection of certain lateral skull base neoplasms. To date, no studies have explored the change of patient-reported quality of life (QoL) after total resection of benign lat…