Shuying Zhang
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View article: Oligodendrocyte Egr2 Mediates the Beneficial Effect of Resocialization on the Social Ability of Socially Isolated Mice
Oligodendrocyte Egr2 Mediates the Beneficial Effect of Resocialization on the Social Ability of Socially Isolated Mice Open
Early social isolation (SI) impairs social ability, which can be partially rescued after resocialization, but the underlying mechanisms have been rarely addressed. This study reported that adolescent SI mice resocialized with group housing…
View article: Glycolytic ATP production enables rapid mammalian cell growth
Glycolytic ATP production enables rapid mammalian cell growth Open
Proliferating cells must produce ATP rapidly enough to meet the energy demands of growth and maintenance. While microbes show a linear coupling between ATP production rate and growth, whether this principle holds in mammalian cells has rem…
View article: Circadian Clock: A Regulator of Immunity in Autoimmune Diseases
Circadian Clock: A Regulator of Immunity in Autoimmune Diseases Open
Aim Autoimmune diseases, characterized by the immune system mistakenly attacking the body's own tissues, are a growing global concern, with increasing prevalence. The circadian clock is a fundamental regulator of physiological processes, c…
View article: Arhgef7 as a key target for enriched environment rescuing spatial cognitive deficits and anxiety-like behaviors in a mouse model of Alzheimer’s disease following early social isolation
Arhgef7 as a key target for enriched environment rescuing spatial cognitive deficits and anxiety-like behaviors in a mouse model of Alzheimer’s disease following early social isolation Open
Arhgef7 in mPFC neurons is essential for the physical components of EE selectively alleviating spatial cognitive deficits and anxiety-like behaviors in early isolated AD model mice, serving as a potential target for the prevention and trea…
View article: The incidence and influencing factors of hypothermia in patients after transurethral prostatectomy: a systematic review and meta—analysis
The incidence and influencing factors of hypothermia in patients after transurethral prostatectomy: a systematic review and meta—analysis Open
View article: Spatio-Temporal Distribution Evolution Characteristics and Geographical Influencing Factors of Cultural Heritage Sites in Xinjiang, China
Spatio-Temporal Distribution Evolution Characteristics and Geographical Influencing Factors of Cultural Heritage Sites in Xinjiang, China Open
Cultural Heritage Sites (CHS) serve as tangible evidence of regional human–environment interactions and spatial representation of historical memory. The research developed a Xinjiang CHS database and integrated geographic information techn…
View article: Deep Learning-Based Optimization Study of Virtual Power Plant Resource Regulation
Deep Learning-Based Optimization Study of Virtual Power Plant Resource Regulation Open
In order to solve the problem that it is difficult to protect privacy in the resource optimization and control of virtual power plants, the research on resource optimization and control of virtual power plants based on deep learning was pr…
View article: Examining the multiscale effects of urban environment on chronic diseases: a case study of hypertension in New York City
Examining the multiscale effects of urban environment on chronic diseases: a case study of hypertension in New York City Open
The growing prevalence of hypertension, a key chronic disease, amidst urbanization is analyzed through spatial similarity and dependence using correlation and spatial autocorrelation. A Multiscale Geographically Weighted Regression (MGWR) …
View article: Comparative Analysis of the Spatial-Temporal Distribution and Influencing Factors of the Tourism Industry in Three Cities along Beijing-Hangzhou Grand Canal in China
Comparative Analysis of the Spatial-Temporal Distribution and Influencing Factors of the Tourism Industry in Three Cities along Beijing-Hangzhou Grand Canal in China Open
The temporal-spatial pattern of linear cultural heritage in the context of the tourism industry is closely linked to heritage management. Using the 1800 km long Beijing-Hangzhou Grand Canal as an example, this study compared the dynamic ev…
View article: Correction: Spatial distribution and pedigree age of intangible cultural heritage along the Grand Canal of China
Correction: Spatial distribution and pedigree age of intangible cultural heritage along the Grand Canal of China Open
View article: Examining the Multiscale Effects of Urban Environment on Chronic Diseases: A Case Study of Hypertension in New York City
Examining the Multiscale Effects of Urban Environment on Chronic Diseases: A Case Study of Hypertension in New York City Open
With the ongoing process of urbanization, the global issue of chronic diseases is becoming increasingly prominent, with rising incidence rates. This study focuses on hypertension, a typical chronic disease, and analyzes the spatial similar…
View article: Exploring the Influence Mechanism of Brand Crisis on Consumer Repurchase Behavior
Exploring the Influence Mechanism of Brand Crisis on Consumer Repurchase Behavior Open
The outbreak of a brand crisis can lead to an increase in public distrust of the brand, a sharp drop in sales, a blow to brand reputation and other phenomena, thus causing consumer dissatisfaction. How to repair the trust between brands an…
View article: Confidence-Enhanced Semi-supervised Learning for Mediastinal Neoplasm Segmentation<sup>1</sup>
Confidence-Enhanced Semi-supervised Learning for Mediastinal Neoplasm Segmentation<sup>1</sup> Open
Automated segmentation of mediastinal neoplasms in preoperative computed tomography (CT) scans is critical for accurate diagnosis. Though convolutional neural networks (CNNs) have proven effective in medical imaging analysis, the segmentat…
View article: Spatial distribution and pedigree age of intangible cultural heritage along the Grand Canal of China
Spatial distribution and pedigree age of intangible cultural heritage along the Grand Canal of China Open
Intangible cultural heritage is the carrier of national memory and a historical witness. Exploring the spatial distribution and chronological evolution of intangible cultural heritage is of great significance to understand the cultural int…
View article: Canal Heritage Tourism Utilization Models: Experience and Inspirations from the Grand Canal (Beijing Section)
Canal Heritage Tourism Utilization Models: Experience and Inspirations from the Grand Canal (Beijing Section) Open
Tourism utilization is an important means for revitalizing canal heritage. Exploring the utilization models of canal heritage tourism is the prerequisite to realizing the sustainable development of canals. Based on previous studies, this s…
View article: Illuminating the Complex Associations Between Job Burnout, Quiet Quitting Intention, and Job Satisfaction in China’s Micro Hospitality Sector
Illuminating the Complex Associations Between Job Burnout, Quiet Quitting Intention, and Job Satisfaction in China’s Micro Hospitality Sector Open
This quantitative study examined the impact of job burnout on quiet quitting intention among 423 employees in micro-entities operating in China's hospitality industry.The four core components of job burnout -emotional exhaustion, mental di…
View article: Analysis of the Explanatory Power of Cognitive Construal Theory on Translator's Subjectivity and Objectivity
Analysis of the Explanatory Power of Cognitive Construal Theory on Translator's Subjectivity and Objectivity Open
View article: Characteristic differences and mechanism of community-concentrated and corridor-expanded canal heritage tourism: Experience and inspirations from the Grand Canal (Beijing Section)
Characteristic differences and mechanism of community-concentrated and corridor-expanded canal heritage tourism: Experience and inspirations from the Grand Canal (Beijing Section) Open
The authors have requested that this preprint be removed from Research Square.
View article: Navigating Risks: Corporate Violations in a Dynamic Business Landscape
Navigating Risks: Corporate Violations in a Dynamic Business Landscape Open
View article: Speciated VOCs emissions and ozone formation potential from on-road vehicles in North China Plain based on detailed and localized source profiles
Speciated VOCs emissions and ozone formation potential from on-road vehicles in North China Plain based on detailed and localized source profiles Open
One of China's most heavily ozone (O3) contaminated regions is the North China Plain (NCP). On-road vehicles are major contributors to volatile organic compound (VOC) emissions. We established localized speciated VOC emission inventories f…
View article: Controlling factors and toxicokinetic modeling of antibiotics bioaccumulation in aquatic organisms: A review
Controlling factors and toxicokinetic modeling of antibiotics bioaccumulation in aquatic organisms: A review Open
Antibiotics are emerging pollutants widely existing in the aquatic environment with adverse effects on both humans and organisms. Understanding bioaccumulation of antibiotics in aquatic organisms is important for their risk assessment. Obs…
View article: Health Risk Assessment and Influencing Factors Analysis of High Temperatures on Negative Emotions
Health Risk Assessment and Influencing Factors Analysis of High Temperatures on Negative Emotions Open
The emotional health of urban residents has been seriously threatened by frequent and normalized heat waves. This study constructed the VI-level assessment standard for emotional health risk using data from satellite images, meteorological…
View article: Network of Tourism–Industrial Complex in Cities: Typologies and Implications through a Critical Literature Review
Network of Tourism–Industrial Complex in Cities: Typologies and Implications through a Critical Literature Review Open
Although tourism has increasingly become an important activity with wide influences on the economic, social, and spatial development of a city, knowledge and interest mostly remain on its industrial performance and promotion. The synergy b…
View article: The Coastal Tourism Climate Index (CTCI): Development, Validation, and Application for Chinese Coastal Cities
The Coastal Tourism Climate Index (CTCI): Development, Validation, and Application for Chinese Coastal Cities Open
Climate is an essential component in the sustainability of tourism cities. Coastal tourism cities face unprecedented challenges under a changing climate. The complexity of the tourism–climate interface predicates the need for tools that ca…
View article: Controlling factors and toxicokinetic modeling of antibiotics bioaccumulation in aquatic organisms: A review
Controlling factors and toxicokinetic modeling of antibiotics bioaccumulation in aquatic organisms: A review Open
Antibiotics are emerging pollutants widely existing in the aquatic environment with adverse effects on both humans and organisms. Understanding bioaccumulation of antibiotics in aquatic organisms is important for their risk assessment. Obs…
View article: Intervention and Sovereignty in Environmental Protection: The Disputation of the Developing Countries’ Role
Intervention and Sovereignty in Environmental Protection: The Disputation of the Developing Countries’ Role Open
The international intervention has been criticized by the developing countries as a political weapon to interfere with their sovereignty by developed countries.This article compares the changing strategies from Trump to the Biden governmen…
View article: A Comparative Study of Customer Perceptions of Urban and Rural Bed and Breakfasts in Beijing: An Analysis of Online Reviews
A Comparative Study of Customer Perceptions of Urban and Rural Bed and Breakfasts in Beijing: An Analysis of Online Reviews Open
The differences between urban and rural B&Bs should be emphasized, which is critical for the sustainable development of the B&B industry. This study identified and compared the topics that customers were concerned about for urban and rural…
View article: Sustainable Development and Tourists' Satisfaction in Historical Districts: Influencing Factors and Features
Sustainable Development and Tourists' Satisfaction in Historical Districts: Influencing Factors and Features Open
Determining how to achieve sustainable development and protection of historical districts is a worthwhile research topic. As a vital way to update urban space, tourism development in historical districts is an effective tool for redistribu…
View article: The development model of homestay tourism agglomeration in Yangtze River Delta from the L-R-D perspective
The development model of homestay tourism agglomeration in Yangtze River Delta from the L-R-D perspective Open
中国民宿发展呈现极强的地理集聚特征,而鉴于民宿与休闲旅游的融合发展,旅游业发达地区对催生民宿 产业则具有直接推动作用。因此,民宿旅游集聚区并不受制于空间尺度的大小 [3,9]
View article: FCB system analysis and performance test results of 1000MW ultra supercritical coal fired power station
FCB system analysis and performance test results of 1000MW ultra supercritical coal fired power station Open
Fast cut back (FCB) function can make the power station restore the external power supply in a very short period of time from the auxiliary power operation conditions through self-help mode. In case of large-scale power grid failure, FCB f…