Shyam Sunder Sharma
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View article: Optimizing the effect of TiO2 nano powder in water-based paint manufacturing using response surface methodology
Optimizing the effect of TiO2 nano powder in water-based paint manufacturing using response surface methodology Open
View article: Phytochemical screening and therapeutic potential of selected medicinal plants
Phytochemical screening and therapeutic potential of selected medicinal plants Open
View article: Cardioprotective potential of shikonin in cardiac hypertrophy is mediated through PKM2/c-Myc/PTBP1/HIF-1α signaling pathway
Cardioprotective potential of shikonin in cardiac hypertrophy is mediated through PKM2/c-Myc/PTBP1/HIF-1α signaling pathway Open
INTRODUCTION: Chronic sympathetic stress contributes significantly to the cardiac hypertrophy (CH) development. Currently, several pharmacological agents and surgical options are available for the treatment of CH. However, available treatm…
View article: Amelioration of Glutamate-induced Toxicity by a New Thyrotropin-releasing Hormone (TRH) Analogue PYR- <scp>l</scp> -(2,5-Dibromo)-His- <scp>l</scp> -ProNH <sub>2</sub>
Amelioration of Glutamate-induced Toxicity by a New Thyrotropin-releasing Hormone (TRH) Analogue PYR- <span>l</span> -(2,5-Dibromo)-His- <span>l</span> -ProNH <sub>2</sub> Open
Background Glutamate has been implicated in the pathophysiology of central nervous system diseases, including stroke. Purpose In this study, the neuroprotective potential of the newly synthesised thyrotropin-releasing hormone (TRH) analogu…
View article: HC070, a Transient Receptor Potential Canonical 5 (TRPC5) Channels Inhibitor Ameliorated α‐synuclein Preformed Fibrils‐Induced Parkinson's Disease: A Neurobehavioural and Mechanistic Study
HC070, a Transient Receptor Potential Canonical 5 (TRPC5) Channels Inhibitor Ameliorated α‐synuclein Preformed Fibrils‐Induced Parkinson's Disease: A Neurobehavioural and Mechanistic Study Open
Alpha‐synuclein pathology is a characteristic feature of Parkinson's disease (PD) and related synucleinopathies. As a result, reducing alpha‐synuclein pathology is one of the mechanisms being looked at for the development of newer agents w…
View article: Imatinib attenuates neurobehavioral deficits and hippocampal neuronal damage after global cerebral ischemia in gerbils
Imatinib attenuates neurobehavioral deficits and hippocampal neuronal damage after global cerebral ischemia in gerbils Open
Imatinib mesylate, a selective tyrosine kinase inhibitor, exhibited beneficial effects against various neurological diseases besides its anticancer activity. However, its effects on global cerebral ischemia in gerbils remain to be investig…
View article: Study on standardization of recipe for betelvine beverage
Study on standardization of recipe for betelvine beverage Open
View article: Performance of different cultivars of chrysanthemum on growth and flowering
Performance of different cultivars of chrysanthemum on growth and flowering Open
View article: Effect of post-harvest treatments on physical properties of Guava cv. Allahabad safeda
Effect of post-harvest treatments on physical properties of Guava cv. Allahabad safeda Open
View article: Transient receptor potential channels as an emerging target for the treatment of Alzheimer's disease: Unravelling the potential of pharmacological interventions
Transient receptor potential channels as an emerging target for the treatment of Alzheimer's disease: Unravelling the potential of pharmacological interventions Open
Alzheimer's disease (AD) is a devastating disorder with a multifaceted aetiology characterized by dementia, which later progresses to cognitive impairment. Significant efforts have been made to develop pharmacological interventions that sl…
View article: Scrub Typhus: An Acute Precipitant for Acute on Chronic Liver Failure
Scrub Typhus: An Acute Precipitant for Acute on Chronic Liver Failure Open
View article: Big Data in Cloud Computing: An Overview
Big Data in Cloud Computing: An Overview Open
Cloud computing is a potent tool for sophisticated and massive-scale computation. It removes the need for expensive hardware, specialized space, and software maintenance. It has been noticed that cloud computing has resulted in a massive i…
View article: Effects of Nutritional Therapy on Sarcopenia in Patients with Liver Cirrhosis- A Randomized Controlled Trial
Effects of Nutritional Therapy on Sarcopenia in Patients with Liver Cirrhosis- A Randomized Controlled Trial Open
View article: Effect of Lifestyle Measures in Normal Body Mass Index Non-alcoholic Fatty Liver Disease Patients
Effect of Lifestyle Measures in Normal Body Mass Index Non-alcoholic Fatty Liver Disease Patients Open
View article: Change in Frailty Status with Nutritional Therapy in Cirrhotic Patient- A Randomized Controlled Trial
Change in Frailty Status with Nutritional Therapy in Cirrhotic Patient- A Randomized Controlled Trial Open
View article: A prospective comparative study of concurrent chemoradiation in advanced carcinoma cervix patients with weekly cisplatin vs. weekly cisplatin and paclitaxel
A prospective comparative study of concurrent chemoradiation in advanced carcinoma cervix patients with weekly cisplatin vs. weekly cisplatin and paclitaxel Open
Background: Cisplatin-based concurrent chemoradiation is the standard treatment for carcinoma cervix. However, there is a need to explore alternative chemotherapeutic agents to further improve the treatment outcome. In this study, weekly p…
View article: Response
Response Open
View article: Pharmacological Modulation of TRPM2 Channels via TRPM2 Pathway Leads to Neuroprotection in MPTP-induced Parkinson’s Disease in Sprague Dawley Rats
Pharmacological Modulation of TRPM2 Channels via TRPM2 Pathway Leads to Neuroprotection in MPTP-induced Parkinson’s Disease in Sprague Dawley Rats Open
Transient receptor potential melastatin-2 (TRPM2) channels are cation channels activated by oxidative stress and adenosine di-phosphate ribose (ADPR ) . Role of TRPM2 channels has been postulated in several neurological disorders, but, it …
View article: IDDF2021-ABS-0035 Opium addiction induced gastric outlet obstruction- an unusual entity
IDDF2021-ABS-0035 Opium addiction induced gastric outlet obstruction- an unusual entity Open
Background There is a paucity of data in the literature on opium addiction causing gastric outlet obstruction. The aim was to study opium addiction causing gastric outlet obstruction and to assess the role of endotherapy. Methods Prospecti…
View article: Influence of Cancer Lagna on Diabetes in Medical Astrology
Influence of Cancer Lagna on Diabetes in Medical Astrology Open
A medical astrologer plays a very important role in maintaining physical and mental health. Based on one's horoscope one can predict when and how one's health will suffer and make the horoscope to be preconscious. The horoscope can predict…
View article: Response
Response Open
View article: Management of walled-off necrosis with nasocystic irrigation with hydrogen peroxide versus biflanged metal stent: randomized controlled trial
Management of walled-off necrosis with nasocystic irrigation with hydrogen peroxide versus biflanged metal stent: randomized controlled trial Open
Background and study aims Walled-off necrosis (WON) is a known complication of acute necrotizing pancreatitis (ANP). There is no study comparing nasocystic irrigation with hydrogen peroxide (H2O2) versus biflanged metal stent (BMS) in the …
View article: Neuroprotective Potential of Caffeic Acid Phenethyl Ester (CAPE) in CNS Disorders: Mechanistic and Therapeutic Insights
Neuroprotective Potential of Caffeic Acid Phenethyl Ester (CAPE) in CNS Disorders: Mechanistic and Therapeutic Insights Open
Neurological disorders like Alzheimer’s disease (AD), Parkinson’s disease (PD), stroke, amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), epilepsy, traumatic brain injury (TBI), depression, and anxiety are responsible for tho…
View article: Seronegative Celiac Disease; Frequently Encountered Yet Undiagnosed Clinical Entity
Seronegative Celiac Disease; Frequently Encountered Yet Undiagnosed Clinical Entity Open
BACKGROUND There are limited studies on the seronegative celiac disease from the Indian subcontinent. The aim of this study was to assess the prevalence, pathological, genetic, and clinical profile of patients with seronegative celiac dise…
View article: Chronic treatment of 4-phenylbutyric acid ameliorates cognitive impairment after focal cerebral ischemia/ reperfusion injury in rats
Chronic treatment of 4-phenylbutyric acid ameliorates cognitive impairment after focal cerebral ischemia/ reperfusion injury in rats Open
Objectives: Stroke, apart from causing physical disabilities, it also often leads to cognitive impairment in patients. At present, there is no effective drug available for the treatment of post-stroke cognitive impairment. The present stud…
View article: Neuroprotective Effect of 2-Aminoethoxydiphenyl Borate (2-APB) in Amyloid β-Induced Memory Dysfunction: A Mechanistic Study
Neuroprotective Effect of 2-Aminoethoxydiphenyl Borate (2-APB) in Amyloid β-Induced Memory Dysfunction: A Mechanistic Study Open
View article: Transient Receptor Potential Channels as an Emerging Target for the Treatment of Parkinson’s Disease: An Insight Into Role of Pharmacological Interventions
Transient Receptor Potential Channels as an Emerging Target for the Treatment of Parkinson’s Disease: An Insight Into Role of Pharmacological Interventions Open
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the symptoms of motor deficits and cognitive decline. There are a number of therapeutics available for the treatment of PD, but most of them suffer from serious side…
View article: Anti-inflammatory Bifidobacterium strains prevent dextran sodium sulfate induced colitis and associated gut microbial dysbiosis in mice
Anti-inflammatory Bifidobacterium strains prevent dextran sodium sulfate induced colitis and associated gut microbial dysbiosis in mice Open
Crohn’s and ulcerative colitis are common inflammatory conditions associated with Inflammatory bowel disease. Owing to the importance of diet based approaches for the prevention of inflammatory gut conditions, the present study was aimed t…
View article: Response to letter on endoscopic ultrasound-guided thrombin injection a management approach for visceral artery pseudoaneurysm: case series
Response to letter on endoscopic ultrasound-guided thrombin injection a management approach for visceral artery pseudoaneurysm: case series Open
Letter to:Response to article on endoscopic ultrasound-guided thrombin injection, a management approach for visceral artery pseudoaneurysmsEndosc Int Open 2020; 08(07): E967-E967DOI: 10.1055/a-1178-9457
View article: Su1251 ENDOSCOPIC ULTRASOUND GUIDED THROMBIN INJECTION A NOVEL MANAGEMENT APPROACH FOR VISCERAL ARTERY PSEUDOANEURYSM
Su1251 ENDOSCOPIC ULTRASOUND GUIDED THROMBIN INJECTION A NOVEL MANAGEMENT APPROACH FOR VISCERAL ARTERY PSEUDOANEURYSM Open