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View article: Comment on Agbaje et al. Persistent Hyperglycemia and Insulin Resistance With the Risk of Worsening Cardiac Damage in Adolescents: A 7-Year Longitudinal Study of the ALSPAC Birth Cohort. Diabetes Care 2025;48:896–904
Comment on Agbaje et al. Persistent Hyperglycemia and Insulin Resistance With the Risk of Worsening Cardiac Damage in Adolescents: A 7-Year Longitudinal Study of the ALSPAC Birth Cohort. Diabetes Care 2025;48:896–904 Open
View article: Performance and limitations of smartwatch estimation of VO2max during free-living activity in non-athletes
Performance and limitations of smartwatch estimation of VO2max during free-living activity in non-athletes Open
Background. Maximal oxygen consumption (VO2max) is the gold standard for assessing cardiorespiratory fitness (CRF), and it is a strong predictor of clinical outcomes, but it is measured during cardiopulmonary exercise testing (C…
View article: Validation of a popular consumer-grade cuffless blood pressure device for continuous 24 h monitoring
Validation of a popular consumer-grade cuffless blood pressure device for continuous 24 h monitoring Open
Aims Hypertension is a leading cause of death worldwide, yet many hypertensive cases remain undiagnosed. Wearable, cuffless blood pressure (BP) monitors could be deployed at scale, but their accuracy remains undetermined. Methods and resul…
View article: A short review of application of near-infrared spectroscopy (NIRS) for the assessment of microvascular post-occlusive reactive hyperaemia (PORH) in skeletal muscle
A short review of application of near-infrared spectroscopy (NIRS) for the assessment of microvascular post-occlusive reactive hyperaemia (PORH) in skeletal muscle Open
Near-infrared spectroscopy (NIRS) is an optical technique that can be used to non-invasively interrogate haemodynamic changes within skeletal muscle. It can be combined with a short (3–5 min) arterial cuff-occlusion to quantify post-occlus…
View article: Differences between brachial and aortic blood pressure in adolescence and their implications for diagnosis of hypertension
Differences between brachial and aortic blood pressure in adolescence and their implications for diagnosis of hypertension Open
Objectives: Blood pressure (BP) is the leading global cause of mortality, and its prevalence is increasing in children and adolescents. Aortic BP is lower than brachial BP in adults. We aimed to assess the extent of this difference and its…
View article: Associations of carotid atherosclerosis with cognitive function and brain health: Findings from a UK tri-ethnic cohort study (Southall and Brent Revisited)
Associations of carotid atherosclerosis with cognitive function and brain health: Findings from a UK tri-ethnic cohort study (Southall and Brent Revisited) Open
This multi-ethnic cohort study provides evidence that presence of carotid plaque, is associated with poorer cognitive function and brain health.
View article: Mechanisms underlying exercise intolerance in Long COVID: an accumulation of multi-system dysfunction
Mechanisms underlying exercise intolerance in Long COVID: an accumulation of multi-system dysfunction Open
The pathogenesis of exercise intolerance and persistent fatigue which can follow an infection with the SARS-CoV-2 virus (’Long COVID’) is not fully understood. Cases were recruited from a Long COVID clinic (N=32; 44±12y; 10(31%)men), and a…
View article: Differences Between Brachial And Aortic Blood Pressure In Adolescence and their implications for diagnosis of hypertension
Differences Between Brachial And Aortic Blood Pressure In Adolescence and their implications for diagnosis of hypertension Open
Objectives Blood pressure is the leading global cause of mortality, and its prevalence is increasing in children and adolescents. Aortic blood pressure (BP) is lower than brachial BP in adults. We aimed to assess the extent of this differe…
View article: A validation study of two wrist worn wearable devices for remote assessment of exercise capacity
A validation study of two wrist worn wearable devices for remote assessment of exercise capacity Open
We determined wearable device errors in assessing a 6-
\nMinute Walk Test (6MWT). 16 healthy adults (male
\n7(44%), mean age±SD 27±4 years) performed a standard
\n(6MWT-S) and modified, ‘free range’, (6MWT-FR)
\nprotocols with a Garmin and…
View article: Association between carotid atherosclerosis and brain activation patterns during the Stroop task in older adults: An fNIRS investigation
Association between carotid atherosclerosis and brain activation patterns during the Stroop task in older adults: An fNIRS investigation Open
View article: No evidence for environmental transmission risk of SARS-CoV-2 in the UK’s largest urban river system: London as a case study
No evidence for environmental transmission risk of SARS-CoV-2 in the UK’s largest urban river system: London as a case study Open
The presence of SARS-CoV-2 in untreated sewage has been confirmed in many countries but its incidence and infection risk in contaminated freshwaters is still poorly understood. The River Thames in the UK receives untreated sewage from 57 C…
View article: Corrigendum: Imaging Protocol, Feasibility, and Reproducibility of Cardiovascular Phenotyping in a Large Tri-Ethnic Population-Based Study of Older People: The Southall and Brent Revisited (SABRE) Study
Corrigendum: Imaging Protocol, Feasibility, and Reproducibility of Cardiovascular Phenotyping in a Large Tri-Ethnic Population-Based Study of Older People: The Southall and Brent Revisited (SABRE) Study Open
CORRECTION article Front. Cardiovasc. Med., 04 November 2021Sec. Cardiovascular Imaging https://doi.org/10.3389/fcvm.2021.769050
View article: Myocardial strain by 3D-speckle tracking echocardiography predicts long-term risk of cardiovascular morbidity and mortality in the general population: the Southall And Brent Revisited (SABRE) study
Myocardial strain by 3D-speckle tracking echocardiography predicts long-term risk of cardiovascular morbidity and mortality in the general population: the Southall And Brent Revisited (SABRE) study Open
Background Both left ventricular (LV) ejection fraction (EF) and Global Longitudinal Strain (GLS) by 2D-echocardiography predict mortality and cardiac events, and GLS may be superior to EF. 3D-speckle tracking echocardiography (3D-STE), a …
View article: YI 1.2 Ideal Cardiovascular Health Score Declines from Adolescence to Emerging Adulthood
YI 1.2 Ideal Cardiovascular Health Score Declines from Adolescence to Emerging Adulthood Open
Purpose To define and compare cardiovascular (CV) health scores (CHS) from adolescence (17 yrs) to emerging adulthood (24 yrs) using longitudinal data from a large British birth cohort. Methods 3142 participants from the Avon Longitudinal …
View article: Imaging Protocol, Feasibility, and Reproducibility of Cardiovascular Phenotyping in a Large Tri-Ethnic Population-Based Study of Older People: The Southall and Brent Revisited (SABRE) Study
Imaging Protocol, Feasibility, and Reproducibility of Cardiovascular Phenotyping in a Large Tri-Ethnic Population-Based Study of Older People: The Southall and Brent Revisited (SABRE) Study Open
Background: People of South Asian and African Caribbean ethnicities living in UK have a high risk of cardiometabolic disease. Limited data exist regarding detailed cardiometabolic phenotyping in this population. Methods enabling this are w…
View article: Imaging protocol, feasibility and reproducibility of cardiovascular phenotyping in a large tri-ethnic population-based study of older people: the Southall and Brent Revisited (SABRE) study
Imaging protocol, feasibility and reproducibility of cardiovascular phenotyping in a large tri-ethnic population-based study of older people: the Southall and Brent Revisited (SABRE) study Open
Background People of South Asian and African Caribbean ethnicities living in UK have a high risk of cardiometabolic disease. Limited data exist regarding detailed cardiometabolic phenotyping in this population. Methods enabling this are wi…
View article: Study Protocol — Insight 46 Cardiovascular: A Sub-study of the MRC National Survey of Health and Development
Study Protocol — Insight 46 Cardiovascular: A Sub-study of the MRC National Survey of Health and Development Open
View article: P97 Age Modifies the Relationship Between Arterial Stiffness, Adiposity and Blood Pressure from Adolescence to Adulthood in Men and Women
P97 Age Modifies the Relationship Between Arterial Stiffness, Adiposity and Blood Pressure from Adolescence to Adulthood in Men and Women Open
View article: 1.1 Differential Changes in Peripheral and Central Blood Pressure from Adolescence to Adulthood
1.1 Differential Changes in Peripheral and Central Blood Pressure from Adolescence to Adulthood Open
Introduction In adults, aging is associated with a rise in blood pressure (BP) and a disproportionate increase in central systolic blood pressure (cSBP) relative to brachial SBP (bSBP) (i.e. reduced aortic to radial pulse pressure amplific…
View article: P97 Age Modifies the Relationship Between Arterial Stiffness, Adiposity and Blood Pressure from Adolescence to Adulthood in Men and Women
P97 Age Modifies the Relationship Between Arterial Stiffness, Adiposity and Blood Pressure from Adolescence to Adulthood in Men and Women Open
Introduction Adult obesity is associated with greater arterial stiffness however in youth the relationship is unclear. We investigated associations between arterial stiffness and adiposity and explored the contribution of blood pressure fr…
View article: P58 Structured Exercise Training is Associated with Better Post Occlusive Reactive Hyperaemia in Skeletal Muscle Measured using Near Infrared Spectroscopy (NIRS)
P58 Structured Exercise Training is Associated with Better Post Occlusive Reactive Hyperaemia in Skeletal Muscle Measured using Near Infrared Spectroscopy (NIRS) Open
Background Participation in structured exercise training may improve microvascular function. Post occlusive reactive hyperaemia (PORH) is a measure of microvascular function in skeletal muscle and can be assessed using near-infrared spectr…
View article: P22 Central and Peripheral Contributions to Submaximal Exercise Performance in Older Adults in the SouthAll and Brent REvisited (SABRE) Study
P22 Central and Peripheral Contributions to Submaximal Exercise Performance in Older Adults in the SouthAll and Brent REvisited (SABRE) Study Open
Background Functional capacity declines with age leading to disability and increased cost of health and social care. In older adults, factors that influence the ability to sustain sub-maximal exercise (a marker of functional capacity) are …
View article: 201Training for a first-time marathon reverses vascular ageing
201Training for a first-time marathon reverses vascular ageing Open
View article: Physiological and Pathophysiological Consequences of a 25-Day Ultra-Endurance Exercise Challenge
Physiological and Pathophysiological Consequences of a 25-Day Ultra-Endurance Exercise Challenge Open
Background: This case-report characterized the respiratory, cardiovascular, and nutritional/gastrointestinal (GI) responses of a trained individual to a novel ultra-endurance exercise challenge. Case Presentation: A male athl…
View article: 11 Novice marathon training reverses vascular ageing
11 Novice marathon training reverses vascular ageing Open
Background Ageing is strongly associated with aortic stiffening, contributing to increased cardiovascular risk even in healthy individuals. Aortic stiffness is reduced in lifelong athletes, but whether training in novice runners can modify…
View article: 133DEPRESSIVE SYMPTOMS ARE ASSOCIATED WITH PERCEIVED, NOT OBJECTIVE, EXERTION DURING EXERCISE IN EUROPEAN, INDIAN ASIAN AND AFRICAN-CARIBBEAN GROUPS
133DEPRESSIVE SYMPTOMS ARE ASSOCIATED WITH PERCEIVED, NOT OBJECTIVE, EXERTION DURING EXERCISE IN EUROPEAN, INDIAN ASIAN AND AFRICAN-CARIBBEAN GROUPS Open
View article: Elevated Blood Pressure in Adolescence Is Attributable to a Combination of Elevated Cardiac Output and Total Peripheral Resistance
Elevated Blood Pressure in Adolescence Is Attributable to a Combination of Elevated Cardiac Output and Total Peripheral Resistance Open
Unlike in older people, it has been suggested that elevated blood pressure (BP) in young people is because of high cardiac output accompanied by normal total peripheral resistance (TPR)—a hyperkinetic/hyperdynamic circulation. We investiga…
View article: P5470Septal hypertrophy in aortic stenosis and its regression after valve replacement is more plastic in males than females: insights from 3D machine learning approach
P5470Septal hypertrophy in aortic stenosis and its regression after valve replacement is more plastic in males than females: insights from 3D machine learning approach Open
View article: P3688Age matters: differences in cardiac response to training in young and middle aged first-time marathon runners
P3688Age matters: differences in cardiac response to training in young and middle aged first-time marathon runners Open
View article: P852Linking myocardial mechanical function to exercise performance: a cardiopulmonary stress echo study in first time London marathon participants
P852Linking myocardial mechanical function to exercise performance: a cardiopulmonary stress echo study in first time London marathon participants Open