Siayareh Rambally
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View article: Mindfulness and yoga therapy for acute pain in sickle cell disease
Mindfulness and yoga therapy for acute pain in sickle cell disease Open
There is a paucity of data regarding the use of non‐pharmacologic therapies for pain in sickle cell disease. The purpose of this pilot study was to assess the acceptability and feasibility of video‐guided mindfulness meditation, breathing …
View article: Bortezomib in relapsed/refractory immune thrombotic thrombocytopenic purpura: A single‐centre retrospective cohort and systematic literature review
Bortezomib in relapsed/refractory immune thrombotic thrombocytopenic purpura: A single‐centre retrospective cohort and systematic literature review Open
Summary Immune thrombotic thrombocytopenic purpura (iTTP) is a rare and life‐threatening haematological condition. Initial treatment involves plasma exchange (PLEX), corticosteroids, caplacizumab and rituximab. In relapsed and refractory c…
View article: Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the <i>EGLN1</i> Gene
Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the <i>EGLN1</i> Gene Open
Hypoxia-inducible factor-1 (HIF-1) is a key regulator of erythropoiesis. In this article, we report 3 novel mutations, P378S, A385T, and G206C, on the EGLN1 gene encoding the negative HIF-1α regulator prolyl hydroxylase domain-2 (PHD2) in …
View article: Resolution of acute hepatitis B-associated aplastic anaemia with antiviral therapy
Resolution of acute hepatitis B-associated aplastic anaemia with antiviral therapy Open
A previously healthy 44-year-old woman presented with 3 days of worsening petechial rash, epistaxis and fatigue. Admission labs revealed pancytopenia, low reticulocyte index and elevated liver enzymes. Bone marrow biopsy demonstrated a pro…