Sibo Tian
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View article: Clinically Interpretable Survival Risk Stratification in Head and Neck Cancer Using Bayesian Networks and Markov Blankets
Clinically Interpretable Survival Risk Stratification in Head and Neck Cancer Using Bayesian Networks and Markov Blankets Open
View article: Structure–Activity Relationship of the Diaminobutyric Acid Residues in Polymyxins
Structure–Activity Relationship of the Diaminobutyric Acid Residues in Polymyxins Open
Multidrug-resistant Gram-negative bacteria have caused a serious threat to global health, and polymyxins are an important last-line therapy. As resistance to polymyxins is emerging, understanding the structure-activity relationship (SAR) o…
View article: Optimizing Lemongrass Disease Detection: A Comparative Analysis of Neural Architecture Search (NAS) with convolutional neural network (CNN) and Transfer Learning models
Optimizing Lemongrass Disease Detection: A Comparative Analysis of Neural Architecture Search (NAS) with convolutional neural network (CNN) and Transfer Learning models Open
Lemongrass is an economically important crop that faces significant disease challenges, making timely and accurate detection crucial for enhancing crop yield and quality. Traditional detection methods rely on manual observation, which can …
View article: Clinical effect of fast-track surgery on laparoscopic treatment of pediatric acute appendicitis and its effect on abdominal inflammation and stress level
Clinical effect of fast-track surgery on laparoscopic treatment of pediatric acute appendicitis and its effect on abdominal inflammation and stress level Open
Objective: To observe the clinical effect of fast-track surgery on laparoscopic treatment of pediatric acute appendicitis and its effect on abdominal inflammation and stress level. Methods: This was a clinical comparative study. Ninety chi…
View article: Comparison of proton and photon therapy in stereotactic arrhythmia radioablation for ventricular tachycardia
Comparison of proton and photon therapy in stereotactic arrhythmia radioablation for ventricular tachycardia Open
Proton therapy for STAR demonstrated significant potential for OARs sparing compared to photon therapy for VT, while maintaining equivalent target coverage. These findings highlight the potential of proton therapy to improve outcomes for V…
View article: Stereotactic Arrhythmia Radioablation for Refractory Ventricular Tachycardia: A Narrative Review and Exploratory Pooled Analysis of Clinical Outcomes and Toxicity.
Stereotactic Arrhythmia Radioablation for Refractory Ventricular Tachycardia: A Narrative Review and Exploratory Pooled Analysis of Clinical Outcomes and Toxicity. Open
STAR is a promising salvage therapy with favorable acute safety and efficacy. Outcome heterogeneity and inconsistent reporting highlight the need for standardized definitions, dosimetric protocols, and longer-term follow-up. Prospective tr…
View article: Requirements and Study Design for the Next Proton FLASH Clinical Trials: an International Multidisciplinary Delphi Consensus
Requirements and Study Design for the Next Proton FLASH Clinical Trials: an International Multidisciplinary Delphi Consensus Open
View article: A Comparative Dosimetric Study of Proton and Photon Therapy in Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia.
A Comparative Dosimetric Study of Proton and Photon Therapy in Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia. Open
Proton therapy for STAR demonstrates significant dosimetric advantages in sparing the heart and other critical OARs compared to photon therapy for VT, while maintaining equivalent target coverage. These findings highlight the potential of …
View article: Integrating knowledge-based planning and noncoplanar oblique VMAT arcs: A study of dose to the heart and immune cells in thoracic radiotherapy
Integrating knowledge-based planning and noncoplanar oblique VMAT arcs: A study of dose to the heart and immune cells in thoracic radiotherapy Open
Cardiac-sparing RapidPlan is a valuable tool for reducing heart dose and lowering EDIC in NSCLC patients. Additional heart sparing is possible by strategically crafting noncoplanar oblique beams to minimize heart dose.
View article: Deciphering Allosteric Modulation of Cancer-Associated Histone Missense Mutations
Deciphering Allosteric Modulation of Cancer-Associated Histone Missense Mutations Open
View article: On Learning Discriminative Features from Synthesized Data for Self-Supervised Fine-Grained Visual Recognition
On Learning Discriminative Features from Synthesized Data for Self-Supervised Fine-Grained Visual Recognition Open
Self-Supervised Learning (SSL) has become a prominent approach for acquiring visual representations across various tasks, yet its application in fine-grained visual recognition (FGVR) is challenged by the intricate task of distinguishing s…
View article: DOSE ESCALATION TRIAL OF PROTON FLASH-RT TO SPINAL CORD IN A LARGE ANIMAL MODEL: QUANTIFICATION OF THE FLASH EFFECT
DOSE ESCALATION TRIAL OF PROTON FLASH-RT TO SPINAL CORD IN A LARGE ANIMAL MODEL: QUANTIFICATION OF THE FLASH EFFECT Open
View article: Immune System Dose With Proton Versus Photon Radiotherapy for Treatment of Locally Advanced NSCLC
Immune System Dose With Proton Versus Photon Radiotherapy for Treatment of Locally Advanced NSCLC Open
IMPT offers a statistically significant reduction in EDIC compared to IMRT. Given the emergence of EDIC as a modifiable prognostic factor in treatment planning, our dosimetric study highlights a potential role for IMPT to address an unmet …
View article: Streamlined pin‐ridge‐filter design for single‐energy proton FLASH planning
Streamlined pin‐ridge‐filter design for single‐energy proton FLASH planning Open
Background FLASH radiotherapy (FLASH‐RT) with ultra‐high dose rate has yielded promising results in reducing normal tissue toxicity while maintaining tumor control. Planning with single‐energy proton beams modulated by ridge filters (RFs) …
View article: EP08.02-37 Definitive Hypofractionated Radiation Therapy with or without Immunotherapy for Stage IIb-III NSCLC: An Institutional Experience
EP08.02-37 Definitive Hypofractionated Radiation Therapy with or without Immunotherapy for Stage IIb-III NSCLC: An Institutional Experience Open
View article: TransFusion: A Practical and Effective Transformer-based Diffusion Model for 3D Human Motion Prediction
TransFusion: A Practical and Effective Transformer-based Diffusion Model for 3D Human Motion Prediction Open
Predicting human motion plays a crucial role in ensuring a safe and effective human-robot close collaboration in intelligent remanufacturing systems of the future. Existing works can be categorized into two groups: those focusing on accura…
View article: Deep learning-based Fast Volumetric Image Generation for Image-guided Proton FLASH Radiotherapy
Deep learning-based Fast Volumetric Image Generation for Image-guided Proton FLASH Radiotherapy Open
Objective: FLASH radiotherapy leverages ultra-high dose-rate radiation to enhance the sparing of organs at risk without compromising tumor control probability. This may allow dose escalation, toxicity mitigation, or both. To prepare for th…
View article: Automatic segmentation of neurovascular bundle on mri using deep learning based topological modulated network
Automatic segmentation of neurovascular bundle on mri using deep learning based topological modulated network Open
Purpose Radiation damage on neurovascular bundles (NVBs) may be the cause of sexual dysfunction after radiotherapy for prostate cancer. However, it is challenging to delineate NVBs as organ‐at‐risks from planning CTs during radiotherapy. R…
View article: Feasibility study of hybrid inverse planning with transmission beams and single‐energy spread‐out Bragg peaks for proton FLASH radiotherapy
Feasibility study of hybrid inverse planning with transmission beams and single‐energy spread‐out Bragg peaks for proton FLASH radiotherapy Open
Background Ultra‐high dose rate (FLASH) proton planning with only transmission beams (TBs) has limitations in normal tissue sparing. The single‐energy spread‐out Bragg peaks (SESOBPs) of the FLASH dose rate have been demonstrated feasible …
View article: Early-Stage Primary Lung Neuroendocrine Tumors Treated With Stereotactic Body Radiation Therapy: A Multi-Institution Experience
Early-Stage Primary Lung Neuroendocrine Tumors Treated With Stereotactic Body Radiation Therapy: A Multi-Institution Experience Open
View article: Definitive intensity modulated proton re-irradiation for lung cancer in the immunotherapy era
Definitive intensity modulated proton re-irradiation for lung cancer in the immunotherapy era Open
Introduction As immunotherapy has improved distant metastasis-free survival (DMFS) in Non-Small Cell Lung Cancer (NSCLC), isolated locoregional recurrences have increased. However, management of locoregional recurrences can be challenging.…
View article: Factors Affecting Clinical Outcomes Among Patients Infected With HIV and Anal Cancer Treated With Modern Definitive Chemotherapy and Radiation Therapy
Factors Affecting Clinical Outcomes Among Patients Infected With HIV and Anal Cancer Treated With Modern Definitive Chemotherapy and Radiation Therapy Open
View article: Ninety‐day mortality following transoral robotic surgery or radiation at Commission on Cancer‐accredited facilities
Ninety‐day mortality following transoral robotic surgery or radiation at Commission on Cancer‐accredited facilities Open
Background Postoperative mortality for oropharynx squamous cell carcinoma (OPSCC) with transoral robotic surgery (TORS) varies from 0.2% to 6.5% on trials; the real‐world rate is unknown. Methods NCDB study from 2010 to 2017 for patients w…
View article: Automated lung tumor delineation on positron emission tomography/computed tomography via a hybrid regional network
Automated lung tumor delineation on positron emission tomography/computed tomography via a hybrid regional network Open
Background Multimodality positron emission tomography/computed tomography (PET/CT) imaging combines the anatomical information of CT with the functional information of PET. In the diagnosis and treatment of many cancers, such as non‐small …
View article: Deep learning-based Fast Volumetric Image Generation for Image-guided Proton FLASH Radiotherapy
Deep learning-based Fast Volumetric Image Generation for Image-guided Proton FLASH Radiotherapy Open
Proton FLASH therapy leverages ultra-high dose-rate radiation to enhance the sparing of organs at risk without compromising tumor control probability. To prepare for the delivery of high doses to targets, we aim to develop a deep learning-…
View article: Feasibility Study of Hybrid Inverse Planning with Transmission Beams and Single-energy Spread-out Bragg Peaks for Proton Flash Radiotherapy
Feasibility Study of Hybrid Inverse Planning with Transmission Beams and Single-energy Spread-out Bragg Peaks for Proton Flash Radiotherapy Open
Ultra-high dose rate (FLASH) proton planning with only transmission beams (TBs) has limitations in normal tissue sparing. The single-energy spread-out Bragg peaks (SESOBPs) of FLASH dose rate have been demonstrated feasible for proton FLAS…
View article: Mutual enhancing learning-based automatic segmentation of CT cardiac substructure
Mutual enhancing learning-based automatic segmentation of CT cardiac substructure Open
Objective. Current segmentation practice for thoracic cancer RT considers the whole heart as a single organ despite increased risks of cardiac toxicities from irradiation of specific cardiac substructures. Segmenting up to 15 different car…
View article: Association of Operability With Post-Treatment Mortality in Early-Stage Non-Small Cell Lung Cancer
Association of Operability With Post-Treatment Mortality in Early-Stage Non-Small Cell Lung Cancer Open
View article: The omission of intentional primary site radiation following transoral robotic surgery in 59 patients: No <scp>local‐regional</scp> failures
The omission of intentional primary site radiation following transoral robotic surgery in 59 patients: No <span>local‐regional</span> failures Open
Background We assessed locoregional control with omission of intentional primary site radiation after transoral robotic surgery (TORS) and quantified nontargeted primary site dose. Methods Following Institutional Review Board (IRB) approva…
View article: Reduced Intubation Rates Following Whole-Lung Low-Dose Radiation Therapy (LD-RT) in Patients With COVID-19-Related Pneumonia
Reduced Intubation Rates Following Whole-Lung Low-Dose Radiation Therapy (LD-RT) in Patients With COVID-19-Related Pneumonia Open