Siddhi P. Jani
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View article: Pancancer network analysis reveals key master regulators for cancer invasiveness
Pancancer network analysis reveals key master regulators for cancer invasiveness Open
View article: Pancancer network analysis reveals key master regulators for cancer invasiveness
Pancancer network analysis reveals key master regulators for cancer invasiveness Open
Background Tumor invasiveness reflects numerous biological changes, including tumorigenesis, progression, and metastasis. To decipher the role of transcriptional regulators (TR) involved in tumor invasiveness, we performed a systematic net…
View article: Computational investigation of natural compounds as potential main protease (Mpro) inhibitors for SARS-CoV-2 virus
Computational investigation of natural compounds as potential main protease (Mpro) inhibitors for SARS-CoV-2 virus Open
View article: Excavating phytochemicals from plants possessing antiviral activities for identifying SARS-CoV hemagglutinin-esterase inhibitors by diligent computational workflow
Excavating phytochemicals from plants possessing antiviral activities for identifying SARS-CoV hemagglutinin-esterase inhibitors by diligent computational workflow Open
Coronaviruses (CoVs) belong to a group of RNA viruses that cause diseases in vertebrates including. Newer and deadlier than SARS CoV-2 are sought to appear in future for which the scientific community must be prepared with the strategies f…
View article: Identification of antiviral phytochemicals as a potential SARS-CoV-2 main protease (Mpro) inhibitor using docking and molecular dynamics simulations
Identification of antiviral phytochemicals as a potential SARS-CoV-2 main protease (Mpro) inhibitor using docking and molecular dynamics simulations Open
Novel SARS-CoV-2, an etiological factor of Coronavirus disease 2019 (COVID-19), poses a great challenge to the public health care system. Among other druggable targets of SARS-Cov-2, the main protease (M pro ) is regarded as a prominent en…
View article: Identification of the Potential Hits for Hindering Interaction of SARS-CoV-2 Main Protease (M pro ) from the Pool of Antiviral Phytochemicals utilizing Molecular Docking and Molecular Dynamics (MD) Simulations
Identification of the Potential Hits for Hindering Interaction of SARS-CoV-2 Main Protease (M pro ) from the Pool of Antiviral Phytochemicals utilizing Molecular Docking and Molecular Dynamics (MD) Simulations Open
The novel SARS-CoV-2 is an etiological factor that triggers Coronavirus disease in 2019 (COVID-19) and tends to be an imminent occurrence of a pandemic. Out of all recognized solved complexes linked to SARS-CoV, Main protease (Mpro) is con…
View article: Molecular Interaction Studies of Natural Compounds against Coronavirus Hemagglutinin-Esterase in complex with ACE2 receptor: An In Silico Approach
Molecular Interaction Studies of Natural Compounds against Coronavirus Hemagglutinin-Esterase in complex with ACE2 receptor: An In Silico Approach Open
The COVID-19 virus emerged as a global health issue and its spike protein requires angiotensin-converting enzyme2 (ACE2) and hemagglutinin-acetylesterase (HE) glycoprotein receptor for cell entry and replication, as revealed by biophysical…