Sidra Hassan
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View article: Reproducibility of spirometry in asthmatic children between 5-12 years of age.
Reproducibility of spirometry in asthmatic children between 5-12 years of age. Open
Objective: To investigate how consistently children (aged 5-12) attending the asthma clinic at Abbasi Shaheed Hospital could perform forced expiratory maneuvers during standard spirometric evaluation. Study Design: Cross-sectional. Setting…
View article: Appraisal of novel azomethine–thioxoimidazolidinone conjugates as ecto-5′-nucleotidase inhibitors: synthesis and molecular docking studies
Appraisal of novel azomethine–thioxoimidazolidinone conjugates as ecto-5′-nucleotidase inhibitors: synthesis and molecular docking studies Open
Azomethine–thioxoimidazolidinone conjugates as ecto-5′-nucleotidase inhibitors.
View article: Vinyl Azides as Radical Acceptors in the Vitamin B<sub>12</sub>-Catalyzed Synthesis of Unsymmetrical Ketones
Vinyl Azides as Radical Acceptors in the Vitamin B<sub>12</sub>-Catalyzed Synthesis of Unsymmetrical Ketones Open
Vinyl azides are very reactive species and as such are useful building blocks, in particular, in the synthesis of N-heterocycles. They can also serve as precursors of ketones. These form in reactions of vinyl azides with nucleophiles or ra…
View article: Ectonucleotidase Inhibitory and Redox Activity of Imidazole‐Based Organic Salts and Ionic Liquids
Ectonucleotidase Inhibitory and Redox Activity of Imidazole‐Based Organic Salts and Ionic Liquids Open
Cytotoxicity against cancer and normal cells, inhibition of ectonucleotidase, and redox properties of a new group of imidazole‐based organic salts and ionic liquids were studied. The tetrachloroferrate salt of a 1‐methylimidazole derivativ…
View article: Synthesis of novel ( <i>E</i> )-1-(2-(2-(4(dimethylamino) benzylidene) hydrazinyl)-4-methylthiazol-5-yl)ethanone derivatives as ecto-5′-nucleotidase inhibitors
Synthesis of novel ( <i>E</i> )-1-(2-(2-(4(dimethylamino) benzylidene) hydrazinyl)-4-methylthiazol-5-yl)ethanone derivatives as ecto-5′-nucleotidase inhibitors Open
Ecto-5′-nucleotidase (e5′NT), a membrane-bound enzyme and an essential member of ecto-nucleotidases which regulates extracellular purinergic signalling. Their upregulation results in various disease conditions, for example, inflammation, h…
View article: Supplementary material from "Synthesis of novel (<i>E</i>)-1-(2-(2-(4(dimethylamino) benzylidene) hydrazinyl) -4-methylthiazol-5-yl)ethanone derivatives as ecto-5′-nucleotidase inhibitors"
Supplementary material from "Synthesis of novel (<i>E</i>)-1-(2-(2-(4(dimethylamino) benzylidene) hydrazinyl) -4-methylthiazol-5-yl)ethanone derivatives as ecto-5′-nucleotidase inhibitors" Open
Ecto-5′-nucleotidase (e5′NT), a membrane-bound enzyme and an essential member of ecto-nucleotidases which regulates extracellular purinergic signalling. Their upregulation results in various disease conditions, for example, inflammation, h…
View article: CCDC 1553903: Experimental Crystal Structure Determination
CCDC 1553903: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1575120: Experimental Crystal Structure Determination
CCDC 1575120: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Synthesis, Structural Elucidation, and Antibacterial Evaluation of Some New Molecules Derived from Coumarin, 1,3,4-Oxadiazole, and Acetamide
Synthesis, Structural Elucidation, and Antibacterial Evaluation of Some New Molecules Derived from Coumarin, 1,3,4-Oxadiazole, and Acetamide Open
Because of the reported biological activities of coumarin, 1,3,4-oxadiazole, and acetamides, some new compounds incorporating these moieties were synthesized and evaluated for their biological potential against Gram-positive and Gram-negat…
View article: Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto‐5′‐nucleotidase
Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto‐5′‐nucleotidase Open
A series of isonicotinohydrazide derivatives was synthesized and tested against recombinant human and rat ecto‐5′‐nucleotidases ( h ‐e5′ NT and r ‐e5′ NT ) and alkaline phosphatase isozymes including both bovine tissue‐non‐specific alkalin…
View article: S-Alkylated/aralkylated 2-(1H-indol-3-yl-methyl)-1,3,4- oxadiazole-5-thiol derivatives. 2. Anti-bacterial, enzymeinhibitory and hemolytic activities
S-Alkylated/aralkylated 2-(1H-indol-3-yl-methyl)-1,3,4- oxadiazole-5-thiol derivatives. 2. Anti-bacterial, enzymeinhibitory and hemolytic activities Open
Purpose: To evaluate the antibacterial, enzyme-inhibitory and hemolytic activities of Salkylated/aralkylated 2-(1H-indol-3-ylmethyl)-1,3,4-oxadiazole-5-thiol derivatives.Methods: Antibacterial activities of the compounds were evaluated usi…
View article: Preliminary structure-activity relationship studies on some novel s-substituted aliphatic analogues of 5-{1-[(4- chlorophenyl) sulfonyl]-3-piperidinyl}-1, 3, 4-oxadiazol-2-yl sulfide
Preliminary structure-activity relationship studies on some novel s-substituted aliphatic analogues of 5-{1-[(4- chlorophenyl) sulfonyl]-3-piperidinyl}-1, 3, 4-oxadiazol-2-yl sulfide Open
Purpose: To study the structure-activity relationships of synthetic multifunctional sulfides through evaluation of lipoxygenase and anti-bacterial activities.Methods: S-substituted derivatives of the parent compound 5-(1-(4- chlorophenylsu…