Explanipedia

A Review of the Latest Updates in Cytogenetic and Molecular Classification and Emerging Approaches in Identifying Abnormalities in Acute Lymphoblastic Leukemia Open

Chaimae El Mahdaoui, Hind Dehbi, Siham Cherkaoui · 2025

Acute lymphoblastic leukemia (ALL) is a heterogeneous hematologic malignancy defined by the uncontrolled proliferation of lymphoid precursors. Accurate diagnosis and effective therapeutic strategies hinge on a comprehensive understanding o…

The first regional interdisciplinary paediatric palliative care (PPC) workshop for the Eastern Mediterranean Region: a groundbreaking collective step for PPC integration Open

Rima Saad Rassam, Ryan R Lion, Siham Cherkaoui, Laila Hessissen, Ximena García , et al. · 2025

Amidst the global disparities in providing Paediatric Palliative Care (PPC), the compounded realities in the Eastern Mediterranean region intensify the need for palliative care for children with cancer. This region hosts 12% of children ne…

Pancytopenia Revealing Medullary Granulomatosis : An Unexpected Diagnosis of Systemic Familial Sarcoidosis Open

M. Bouwe Abdou, M. Cheikhna, I. Oubah, S. Berrada, A. Ben Moussa , et al. · 2025

Sarcoidosis is a granulomatous disease of unknown origin, characterized by highly variable clinical presentations. Diagnosis is based on compatible clinical features, the presence of non-caseating granulomas on biopsy, and the exclusion of…

Primary Adrenal Insufficiency in Children: Adrenoleukodystrophy as a Rare Etiology in Girls Open

HOUDA BOUAICHI, Siham Cherkaoui, S. Abourazak -, Moustapha Hida · 2025

X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disease due to a mutation in the ABCD1 gene that leads to the accumulation of very-long-chain fatty acids in tissues. X-linked adrenoleukodystrophy (X-ALD) is a rare metabolic disorder…

Ovarian relapse in a child with B-ALL: a case report Open

M. Cheikhna, Chaimae El Mahdaoui, N. Bennani Guebessi, Amine Ali Zeggwagh, Nisrine Khoubila , et al. · 2025

This case presents an 8-year-old girl diagnosed with B-cell acute lymphoblastic leukemia (B-ALL), who relapsed after 3 years of treatment and 1 year of complete remission, with an unusual extramedullary relapse in the ovary. Ovarian relaps…

Immune Thrombocytopenic Purpura Complicated by Pituitary Apoplexy: 5th Case Worldwide Open

Siham Cherkaoui, Zineb El Azime -, Amine Essafi -, Hayat Aynaou -, Houda Salhi - , et al. · 2024

Background: Pituitary apoplexy (PA) is an uncommon condition that may arise as a consequence of immune thrombocytopenic purpura (ITP). It is typically observed in the context of pituitary adenoma. The condition may manifest with symptoms o…

A Review of Emerging Cytogenetic and Molecular Approaches in Identifying Abnormalities in Acute Lymphoblastic Leukemia Open

Chaimae El Mahdaoui, Hind Dehbi, Siham Cherkaoui · 2024

Acute Lymphoblastic Leukemia (ALL) is a diverse hematologic malignancy characterized by the uncontrolled proliferation of lymphoid precursors. A comprehensive understanding of the genetic alterations associated with ALL is crucial for accu…

Amylose amyloid light-chain (AL) et lymphome folliculaire: à propos d´un cas Open

Amine Benmoussa, Hajar Maatoui-Belabbes, Reda Allali, Meriem Regragui, Meriem Qachouh , et al. · 2024

The association of light-chain (AL) amyloidosis with type B follicular lymphoma is extremely rare, as the clone secreting the amyloidogenic light chain is generally plasmacytic. We here report the case of a 67-year-old patient with no spec…

t(1;4) translocation in a child with acute lymphoblastic leukemia: a case report Open

Chaimae El Mahdaoui, Nezha Hda, Bouchra Oukkache, Hind Dehbi, Nisrine Khoubila , et al. · 2023

Background Acute lymphoblastic leukemia is the most common childhood cancer, with an 80% frequency in children between 1 and 10 years old. The outcome and prognosis of acute lymphoblastic leukemia in children depends on various factors, su…

Epidemiological and clinical characteristics of children with peripheral neuroblastic tumors: a study on a Moroccan population Open

Aroua Anissi Eddaibouni, N. Bennani Guebessi, Siham Cherkaoui, Mehdi Karkouri, Nisrine Khoubila , et al. · 2023

IBCL-328 Follicular Lymphoma: Concentric Study in the Hematology Department of the IBN ROCHD University Hospital Center Open

Hajar Maataoui-Belabbes, Meryem Qachouh, Nassima Moufid, Amine Benmoussa, Mouna Lamchahab , et al. · 2023

HL-326 Disseminated Pediatric Hodgkin Lymphoma (HL): Concentric Study Within the Hematology Department at Ibn Rochd University Hospital Open

Hajar Maataoui-Belabbes, Ibtissam El Bejjaj, Amine Benmoussa, Meryem Qachouh, Mouna Lamchahab , et al. · 2023

ALL-379 Acute Undifferentiated Leukemia: Rare Clinical Case Open

Nassima Moufid, Chaimae El Mahdaoui, Siham Cherkaoui, Amine Benmoussa, Mouna Lamchahab , et al. · 2023

HL-357 Localized Hodgkin Lymphoma (HL) in Children: Retrospective Study Open

Ibtissam El Bejjaj, Nissrine Khoubila, Hajar Maataoui Belaabes, Siham Cherkaoui, Meryem Qachouh , et al. · 2023

POSTER: MM-317 Non-Cryopreserved Hematopoietic Stem Cells Autotransplantation in Patients With Multiple Myeloma (MM) Aged 65 and Older Open

Nassima Moufid, Sofia Sraidi, Amine Benmoussa, Mouna Lamchahab, Siham Cherkaoui , et al. · 2023

ABCL-411 Management of DLBCL (Diffuse Large B-Cell Lymphoma): A Monocentric Experience Open

Kawtar Tlohi, Amine Benmoussa, Asmaa Harrach, Mouna Lamchahab, Mohamed Rachid , et al. · 2023

CML-294 Chronic Myeloid Leukemia of the Elderly Over 60 Years: Epidemiological, Cytogenetic, and Therapeutic Profile in CASABLANCA Open

Ibtissam El Bejjaj, Meryem Qachouh, Sara Naim, Mohamed Rachid, Mouna Lamchahab , et al. · 2023

IBCL-318 Epidemiological, Clinical, Histopathologic and Therapeutic Characteristics of Marginal Zone Lymphoma: Experience of the Hematology Department of Casablanca in Morocco Open

Nassima Moufid, Meryem Qachouh, Hajar Maataoui-Belabbes, Amine Benmoussa, Nissrine Khoubila , et al. · 2023

POSTER: IBCL-318 Epidemiological, Clinical, Histopathologic and Therapeutic Characteristics of Marginal Zone Lymphoma: Experience of the Hematology Department of Casablanca in Morocco Open

Nassima Moufid, Meryem Qachouh, Hajar Maataoui-Belabbes, Amine Benmoussa, Nissrine Khoubila , et al. · 2023

POSTER: HL-357 Localized Hodgkin Lymphoma (HL) in Children: Retrospective Study Open

Ibtissam El Bejjaj, Nissrine Khoubila, Hajar Maataoui Belaabes, Siham Cherkaoui, Meryem Qachouh , et al. · 2023

MM-317 Non-Cryopreserved Hematopoietic Stem Cells Autotransplantation in Patients With Multiple Myeloma (MM) Aged 65 and Older Open

Nassima Moufid, Sofia Sraidi, Amine Benmoussa, Mouna Lamchahab, Siham Cherkaoui , et al. · 2023

POSTER: IBCL-417 Primary Intracranial Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue in Cerebral Localization: Case Report Open

Kawtar Tlohi, Amine Benmoussa, Mouna Lamchahab, Mohamed Rachid, Meryem Qachouh , et al. · 2023

Lymphome B diffus à grandes cellules splénique primitif : une cause rare de splénomégalie isolée Open

Amine Benmoussa, Kawtar Tlohi, Maryam Qachouh, Nisrine Khoubila, Siham Cherkaoui , et al. · 2023

Primary splenic non-Hodgkin lymphoma is extremely rare, characterized by isolated splenic disease without other lymphoma locations. It’s most often revealed by isolated splenomegaly. We report the case of a 43-year-old female patient with …

Pain assessment and management in the Moroccan haemophilia population: a prospective descriptive study Open

Sofia Sraidi, Sara Naim, Mouna Lamchahab, Siham Cherkaoui, Meryem Qachouh , et al. · 2023

Introduction For people with haemophilia (PwH) who live in developing countries, haemophilia continues to be a condition with serious medical and social consequences. In Morocco, the efforts of patient associations and medical teams have l…

Epidemiology and Outcome of Primary Cerebral Lymphoma in Immunocompetent Patients: A Monocentric Study Open

Fatima Ezzahra Rida, Asmaa Harrach, Mouna Lamchahab, Mohammed Rachid, Nissrine Khoubila , et al. · 2022

Primary cerebral lymphoma (PCL) is a form of extranodal non-Hodgkin’s lymphoma with a poor prognosis. Very few cohorts have been reported in the literature. It is a rare form in 1% of extranodal lymphomas, and 3% to 4% of brain tumors. The…

Evaluation of Therapeutic Results of A Series of Moroccan Patients Aged 20 To 60 Years Treated According To The Acute Myeloid Leukaemia 03 Protocol At The Paediatric Haematology Oncology Centre In Casablanca Open

Marielle Igala, Mouna Lamchahab, Siham Cherkaoui, Nisrine Khoubila, Bouchra Oukkache , et al. · 2021

Acute Myeloblastic Leukaemia (AML) is a malignant haemopathy characterized by infiltration and accumulation in the bone marrow by myeloblastic-type blast cells causing medullary insufficiency. At the global level, the search for improved A…

Current Cytogenetic Abnormalities in Acute Myeloid Leukemia Open

Mounia Bendari, Nisrine Khoubila, Siham Cherkaoui, Nezha Hda, Meryem Qachouh , et al. · 2020

Cytogenetic abnormalities are frequently reported in the literature describing the presence of chromosomal rearrangements in important cases of acute myeloid leukemia (AML); the rate can reach 50–60% of cases of AML. Cytogenetic abnormalit…

A challenging management of hemophilia B patient with inhibitors undergoing major orthopedic surgeries in a resource‐constrained country Open

Wafaa Matrane, Afak Nsiri, Mohamed Rafai, F. El Midmani, Nada Boughaza , et al. · 2020

In this paper, we report a life‐threatening condition and relate our experience in managing a hemophilia B patient who required three surgical procedures, highlighting the difficulties we encountered in our setting and propose some tangibl…

Peripheral Medulloepithelioma: A Rare Entity to Know Open

Wafaa Matrane, Siham Cherkaoui, Meriem Regragui, N. Bennani Guebessi, Mehdi Karkouri , et al. · 2020

According to the World Health Organization, medulloepithelioma belongs to the embryonal neoplasm entity. It is a very rare, highly malignant tumor typically affecting infants and young children. Usually, the tumor arises in the eye or in t…

AMYLOSE CONJONCTIVALE: PREMIERE MANIFESTATION D’UNE AMYLOSE SYSTEMIQUE ASSOCIEE AU MYELOME MULTIPLE Open

Wafaa Matrane, Mouna Lamchahab, B. Allali, Mohamed Rachid, Meryem Qachouh , et al. · 2020

Introduction L’amylose systémique de type AL a été décrite dans presque tous les organes. Cependant l’atteinte conjonctivale est relativement rare et décrite le plus souvent sous forme de cas isolés et petites séries de cas. Elle est le pl…

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