Explanipedia

Subclonal emergence of polycythemia vera, chronic myelomonocytic leukemia, and chronic myeloid leukemia Open

Violaine Tran Quang, J Crétin, Romain Loyaux, Bilel Ben Jedidia, Sihem Tarfi , et al. · 2025

The present longitudinal study reports a unique patient followed over almost three decades who sequentially developed polycythemia vera, chronic myelomonocytic leukemia, and chronic myeloid leukemia. The patient received successive hydroxy…

Clinical and biological characteristics of patients presenting with carcinocythaemia: A retrospective, multicentre study by the French‐speaking Cellular Hematology Group (GFHC) Open

Ludovic Suner, Élise Sourdeau, Thimali Ranaweera, Sihem Tarfi, Emilie Ronez , et al. · 2024

Letter to the editor

TET2 mutational status affects myelodysplastic syndrome evolution to chronic myelomonocytic leukemia Open

Violaine Tran Quang, Benjamin Podvin, Christophe Desterke, Sihem Tarfi, Quentin Barathon , et al. · 2023

International audience

Issue Information Open

Wolfgang Kern, Arjan van de Loosdrecht, Frederic Boston, Jan W. Gratama, Marie C. Béné , et al. · 2023

Correction to "Flow cytometry to detect bone marrow involvement by follicular lymphoma" Volume 104, Number 2 was mailed the week of March 20, 2023.On the cover: Assessment of aberrant HSPC in paired MDS and secondary AML samples.(a) Data f…

Four genetic red cell disorders in one Open

Sihem Tarfi, Bouchra Badaoui · 2023

Issue Information Open

Wolfgang Kern, Arjan van de Loosdrecht, Frederic Boston, Jan W. Gratama, Marie C. Béné , et al. · 2023

Evaluation of two new highly multiplexed PCR assays as an alternative to next‐generation sequencing for IDH1/2 mutation detection Open

Loëtitia Favre, Nouhoum Sako, Sihem Tarfi, Violaine Tran Quang, Corine Joy , et al. · 2022

IDH1 and IDH2 somatic mutations have been identified in solid tumors and blood malignancies. The development of inhibitors of mutant IDH1 and IDH2 in the past few years has prompted the development of a fast and sensitive assay to detect I…

Fusion Gene Detection and Quantification by Asymmetric Capture Sequencing (aCAP-Seq) Open

Guillaume Gricourt, Violaine Tran Quang, Jean‐Michel Cayuela, Elisa Boudali, Sihem Tarfi , et al. · 2022

Several fusion genes such as BCR::ABL1, FIP1L1::PDGFRA, and PML::RARA are now efficiently targeted by specific therapies in patients with leukemia. Although these therapies have significantly improved patient outcomes, leukemia relapse and…

Disappearance of slan-positive non-classical monocytes for diagnosis of chronic myelomonocytic leukemia with an associated inflammatory state Open

Sihem Tarfi, Bouchra Badaoui, Nicolas Freynet, Margot Morabito, Jeffie Lafosse , et al. · 2019

International audience

Optimization of CSF biological investigations for CNS lymphoma diagnosis Open

Marine Armand, Myrto Costopoulos, Jennifer Osman, Sihem Tarfi, Caroline Houillier , et al. · 2019

Diagnosis of lymphoma leptomeningeal dissemination is challenging and relies on a wide array of methods. So far, no consensus biological guidelines are available. This increases the chance of intra‐ and interpractice variations, despite th…

Azurophilic granular blasts are not always part of myeloid lineage: an atypical case of BCP acute lymphoblastic leukemia Open

Coralie Derrieux, Sihem Tarfi · 2019

![Figure][1] A 53-year-old woman presented with asthenia, fever, and pancytopenia. The peripheral blood smear showed 32% large blasts containing many, often clustered, azurophilic granules and multiple vacuoles (panels A-C; May-Grunwald-…

Multicenter validation of the flow measurement of classical monocyte fraction for chronic myelomonocytic leukemia diagnosis Open

Sihem Tarfi, Véronique Harrivel, Florent Dumézy, Julien Guy, Mikaël Roussel , et al. · 2018

High sensitivity of the Hematoflow™ solution for chronic myelomonocytic leukemia screening Open

Romain Vazquez, Mikaël Roussel, Bouchra Badaoui, Nicolas Freynet, Sihem Tarfi , et al. · 2017

Background Accumulation of classical monocytes CD14 ++ CD16 – (also called MO1) ≥ 94% can accurately distinguish chronic myelomonocytic leukemia (CMML) from reactive monocytosis. The HematoFlow™ solution, able to quantify CD16 negative mon…

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