Silvia Capriello
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View article: CD20 + T lymphocytes in isolated Hashimoto’s thyroiditis and type 3 autoimmune polyendocrine syndrome: a pilot study
CD20 + T lymphocytes in isolated Hashimoto’s thyroiditis and type 3 autoimmune polyendocrine syndrome: a pilot study Open
Background CD20 + T cells represent up to 5% of circulating T lymphocytes. These cells have been shown to produce higher levels of IL-17A and IFN-γ than those of CD20 − T lymphocytes. Some reports described the role of CD20 + T cells in au…
View article: The relationship between thyroid disorders and vitamin A.: A narrative minireview
The relationship between thyroid disorders and vitamin A.: A narrative minireview Open
The terms “vitamin A” and “retinoids” encompass a group of fat-soluble compounds essential for human nutrition. Some of them (retinol, retinal, 9-cis-retinoic acid, tretinoin, and 13-cis-retinoic acid) are fully natural, while others are s…
View article: Daily requirement of softgel thyroxine is independent from gastric juice pH
Daily requirement of softgel thyroxine is independent from gastric juice pH Open
Background Softgel levothyroxine (LT4) preparation showed a better in vitro dissolution profile at increasing pH as compared to tablet LT4 preparation. Clinical studies suggested a better performance of softgel LT4 preparation in patients …
View article: Regulatory B Cells in Systemic Sclerosis Isolated or Concomitant With Hashimoto Thyroiditis
Regulatory B Cells in Systemic Sclerosis Isolated or Concomitant With Hashimoto Thyroiditis Open
Systemic sclerosis (SSc) is a systemic autoimmune disease in which gastrointestinal disorders represent a complication in up to 90% of patients. SSc may associate with thyroid autoimmune disorders, with Hashimoto’s thyroiditis (HT) being t…
View article: Levothyroxine Therapy in Gastric Malabsorptive Disorders
Levothyroxine Therapy in Gastric Malabsorptive Disorders Open
Oral levothyroxine sodium is absorbed in the small intestine, mainly in the jejunum and the ileum being lower the absorption rate at duodenal level. The time interval between the ingestion of oral thyroxine and its appearance in the plasma…
View article: Recurrent Pregnancy Loss in Women with Hashimoto's Thyroiditis with Concurrent Non-Endocrine Autoimmune Disorders
Recurrent Pregnancy Loss in Women with Hashimoto's Thyroiditis with Concurrent Non-Endocrine Autoimmune Disorders Open
Background: An increased rate of recurrent miscarriage has been described in patients with autoimmune thyroid disease. However, there is a lack of studies that assess the rate of recurrent pregnancy loss (RPL) in patients with Hashimoto's …
View article: Ulcerative Colitis as a Novel Cause of Increased Need for Levothyroxine
Ulcerative Colitis as a Novel Cause of Increased Need for Levothyroxine Open
Background: Thyroxine absorption takes place at the small intestine level and several disorders affecting this intestinal tract lead to thyroxine malabsorption. An increased need for thyroxine has also been observed in gastric disorders du…
View article: Hashimoto’s Thyroiditis and Autoimmune Gastritis
Hashimoto’s Thyroiditis and Autoimmune Gastritis Open
The term "thyrogastric syndrome" defines the association between autoimmune thyroid disease and chronic autoimmune gastritis (CAG), and it was first described in the early 1960s. More recently, this association has been included in polygla…
View article: Early detection of biochemically occult autonomous thyroid nodules
Early detection of biochemically occult autonomous thyroid nodules Open
Objective Autonomously functioning thyroid areas may be associated with subclinical or overt hyperthyroidism, but may exist even in the presence of normal TSH. This study was aimed at comparing the rate of autonomously functioning areas an…