Silvia Marino
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View article: The Evolution of Telemedicine in Pre-Post COVID-19 Period
The Evolution of Telemedicine in Pre-Post COVID-19 Period Open
Introduction In recent years, telemedicine has become increasingly widespread, with a marked rise in adoption during the COVID-19 pandemic. During the period of restrictions, telemedicine resulted to be particularly useful for managing var…
View article: Molecular and Neurobiological Imbalance from the Use of Technological Devices During Early Child Development Stages
Molecular and Neurobiological Imbalance from the Use of Technological Devices During Early Child Development Stages Open
Background/Objectives: Digital technologies have become increasingly integrated into the daily lives of children and adolescents, largely because their interactive and visually engaging design is particularly suited to the younger users. T…
View article: Thalamus and consciousness: a systematic review on thalamic nuclei associated with consciousness
Thalamus and consciousness: a systematic review on thalamic nuclei associated with consciousness Open
Introduction Consciousness relies on both cortical and subcortical structures and their feedforward and feedback pathways. Within this framework, the thalamus represents a relay station enabling the transmission, reception, and integration…
View article: The Role of Near-Infrared Spectroscopy (NIRS) in Neurological and Neurodegenerative Diseases as Support to Clinical Practice: An Overview of the Literature
The Role of Near-Infrared Spectroscopy (NIRS) in Neurological and Neurodegenerative Diseases as Support to Clinical Practice: An Overview of the Literature Open
Near-Infrared Spectroscopy (NIRS) is a non-invasive technique that measures the oxygenation variations of brain tissue in response to different stimuli. It has many advantages such as being easy to use, portable, and non-invasive. Several …
View article: Real-World Experience with the Available Outpatient COVID-19 THErapies in Patients with canceR (CO.THER)
Real-World Experience with the Available Outpatient COVID-19 THErapies in Patients with canceR (CO.THER) Open
Background/Objectives: Cancer represents an important risk factor for acquiring severe acute respiratory syndrome by Coronavirus-2 (SARS-CoV-2) and subsequent hospitalization. The utility of early antiviral therapies, including their prote…
View article: LONG-NEXT: A new accurate and efficient NGS-based method for GBA1 analysis in Parkinson disease
LONG-NEXT: A new accurate and efficient NGS-based method for GBA1 analysis in Parkinson disease Open
View article: Executive Functions Training Improves Language Abilities in Aphasia Rehabilitation: A Systematic Review
Executive Functions Training Improves Language Abilities in Aphasia Rehabilitation: A Systematic Review Open
Background/Objectives: In recent years, the popularity of non-verbal cognitive training for aphasia has increased. Building on evidence that language abilities engage brain areas involved in executive functions (EFs) processing, this revie…
View article: DANCE Rehabilitation EXperience (DANCEREX-DTx): Protocol for a randomized controlled trial on effectiveness of digital therapeutics in chronic neurological disabilities.
DANCE Rehabilitation EXperience (DANCEREX-DTx): Protocol for a randomized controlled trial on effectiveness of digital therapeutics in chronic neurological disabilities. Open
With DANCEREX-DTx, we aspire to change the hospital-centered paradigm of rehabilitation care to bring it to the patients' homes, making them active in their treatment path and promoting motivation and adherence to treatment from the initia…
View article: A feasibility and usability study of a virtual reality tool (VESPA 2.0) for cognitive rehabilitation in patients with mild cognitive impairment: an ecological approach
A feasibility and usability study of a virtual reality tool (VESPA 2.0) for cognitive rehabilitation in patients with mild cognitive impairment: an ecological approach Open
Introduction Mild cognitive impairment (MCI) or “mild neurocognitive disorder” represents an intermediate status between normality and dementia. It is characterized by cognitive decline that does not significantly interfere with normal dai…
View article: Principal Component Analysis to Identify Parameters in MRgFUS Treatment
Principal Component Analysis to Identify Parameters in MRgFUS Treatment Open
Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) is a relatively new treatment which combines the precision of radiological imaging with the therapeutic potential of focused ultrasound, promising a non-invasive treatment for d…
View article: Importance of Coping Strategies on Quality of Life in People with Multiple Sclerosis: A Systematic Review
Importance of Coping Strategies on Quality of Life in People with Multiple Sclerosis: A Systematic Review Open
Multiple sclerosis (MS) is a neurodegenerative disorder of the central nervous system characterized by a variety of symptoms such as fatigue, spasticity, tremors, and cognitive disorders. Individuals with MS may employ different coping str…
View article: Psychological Factors Affecting Assertiveness in Subjects with Parkinson’s Disease
Psychological Factors Affecting Assertiveness in Subjects with Parkinson’s Disease Open
Background/Objectives: Assertiveness, defined as the positive affirmation of oneself, encompasses the ability to refuse requests, express anger, disagree or oppose others, show affection, and uphold personal beliefs without causing conflic…
View article: Towards a Deeper Understanding: Utilizing Machine Learning to Investigate the Association between Obesity and Cognitive Decline—A Systematic Review
Towards a Deeper Understanding: Utilizing Machine Learning to Investigate the Association between Obesity and Cognitive Decline—A Systematic Review Open
Background/Objectives: Several studies have shown a relation between obesity and cognitive decline, highlighting a significant global health challenge. In recent years, artificial intelligence (AI) and machine learning (ML) have been integ…
View article: The Role of Treatment-Related Parameters and Brain Morphology in the Lesion Volume of Magnetic-Resonance-Guided Focused Ultrasound Thalamotomy in Patients with Tremor-Dominant Neurological Conditions
The Role of Treatment-Related Parameters and Brain Morphology in the Lesion Volume of Magnetic-Resonance-Guided Focused Ultrasound Thalamotomy in Patients with Tremor-Dominant Neurological Conditions Open
Purpose: To determine the best predictor of lesion volume induced by magnetic resonance (MR)-guided focused ultrasound (MRgFUS) thalamotomy in patients with tremor-dominant symptoms in Parkinson’s disease (PD) and essential tremor (ET) pat…
View article: The Lack of Ad Hoc Neuropsychological Assessment in Adults with Neurofibromatosis: A Systematic Review
The Lack of Ad Hoc Neuropsychological Assessment in Adults with Neurofibromatosis: A Systematic Review Open
Background: Neurofibromatosis Type 1 (NF1) is a genetic autosomal dominant disorder that affects both the central and peripheral nervous systems. Children and adolescents with NF1 commonly experience neuropsychological, motor, and behavior…
View article: Applications of Artificial Intelligence in the Neuropsychological Assessment of Dementia: A Systematic Review
Applications of Artificial Intelligence in the Neuropsychological Assessment of Dementia: A Systematic Review Open
In the context of advancing healthcare, the diagnosis and treatment of cognitive disorders, particularly Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD), pose significant challenges. This review explores Artificial Intelligenc…
View article: Author Correction: Differential diagnosis of neurodegenerative dementias with the explainable MRI based machine learning algorithm MUQUBIA
Author Correction: Differential diagnosis of neurodegenerative dementias with the explainable MRI based machine learning algorithm MUQUBIA Open
View article: Dataset related to article "Patient-reported outcome measures in patients with familial cerebral cavernous malformations: results from the Treat_CCM trial"
Dataset related to article "Patient-reported outcome measures in patients with familial cerebral cavernous malformations: results from the Treat_CCM trial" Open
Excel file with data related to the article.
View article: Dataset related to article "Patient-reported outcome measures in patients with familial cerebral cavernous malformations: results from the Treat_CCM trial"
Dataset related to article "Patient-reported outcome measures in patients with familial cerebral cavernous malformations: results from the Treat_CCM trial" Open
Excel file with data related to the article.
View article: Neuroinflammaging: A Tight Line Between Normal Aging and Age-Related Neurodegenerative Disorders
Neuroinflammaging: A Tight Line Between Normal Aging and Age-Related Neurodegenerative Disorders Open
Aging in the healthy brain is characterized by a low-grade, chronic, and sterile inflammatory process known as neuroinflammaging. This condition, mainly consisting in an up-regulation of the inflammatory response at the brain level, contri…
View article: An alternative approach in the skull density ratio (SDR) computation used in MRgFUS treatments: A preliminary study
An alternative approach in the skull density ratio (SDR) computation used in MRgFUS treatments: A preliminary study Open
Magnetic Resonance guided Focused Ultrasound (MRgFUS) is a hybrid technique used for surgery lesioning treatment for brain disorders. Morphological information is obtained from MR images, while the ablative process is performed with US. Th…
View article: Possible Implications of Managing Alexithymia on Quality of Life in Parkinson’s Disease: A Systematic Review
Possible Implications of Managing Alexithymia on Quality of Life in Parkinson’s Disease: A Systematic Review Open
Alexithymia, characterized by difficulty in recognizing and verbalizing emotions, is reported to be more prevalent in subjects with Parkinson’s disease (PD) than in the general population. Although it is one of the nonmotor symptoms of PD,…
View article: Circulating biomarkers in familial cerebral cavernous malformation
Circulating biomarkers in familial cerebral cavernous malformation Open
View article: Changes in cerebral cortex activity during a simple motor task after MRgFUS treatment in patients affected by essential tremor and Parkinson's disease: a pilot study using functional NIRS
Changes in cerebral cortex activity during a simple motor task after MRgFUS treatment in patients affected by essential tremor and Parkinson's disease: a pilot study using functional NIRS Open
Objective. Magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) is a non-invasive thermal ablation method that involves high-intensity focused ultrasound surgery (FUS) and Magnetic Resonance Imaging for anatomical imaging …
View article: Persistent Müllerian Duct Syndrome and Germ Cell Tumor: A Case Report and a Review of the Literature
Persistent Müllerian Duct Syndrome and Germ Cell Tumor: A Case Report and a Review of the Literature Open
Persistent Müllerian Duct Syndrome (PMDS) is a rare disease of sexual differentiation characterized by the presence of Müllerian duct structures in a male with a normal phenotype. All patients with this condition are considered males regar…
View article: MR-Guided Focused Ultrasound for Refractory Epilepsy: Where Are We Now?
MR-Guided Focused Ultrasound for Refractory Epilepsy: Where Are We Now? Open
Epilepsy is one of the most common neurological diseases in both adults and children. Despite improvements in medical care, 20 to 30% of patients are still resistant to the best medical treatment. The quality of life, neurologic morbidity,…
View article: Differential diagnosis of neurodegenerative dementias with the explainable MRI based machine learning algorithm MUQUBIA
Differential diagnosis of neurodegenerative dementias with the explainable MRI based machine learning algorithm MUQUBIA Open
View article: Paving the Way for Predicting the Progression of Cognitive Decline: The Potential Role of Machine Learning Algorithms in the Clinical Management of Neurodegenerative Disorders
Paving the Way for Predicting the Progression of Cognitive Decline: The Potential Role of Machine Learning Algorithms in the Clinical Management of Neurodegenerative Disorders Open
Alzheimer’s disease (AD) is the most common form of neurodegenerative disorder. The prodromal phase of AD is mild cognitive impairment (MCI). The capacity to predict the transitional phase from MCI to AD represents a challenge for the scie…
View article: Neural Plasticity Changes Induced by Motor Robotic Rehabilitation in Stroke Patients: The Contribution of Functional Neuroimaging
Neural Plasticity Changes Induced by Motor Robotic Rehabilitation in Stroke Patients: The Contribution of Functional Neuroimaging Open
Robotic rehabilitation is one of the most advanced treatments helping people with stroke to faster recovery from motor deficits. The clinical impact of this type of treatment has been widely defined and established using clinical scales. T…
View article: Late‐breaking Abstracts
Late‐breaking Abstracts Open
Background and aims: Benign paroxysmal positional vertigo (BPPV), affecting c. 50% acute moderate-severe traumatic brain injury patients, is recurrent and linked to falls.Falls are linked to excess mortality in TBI survivors, suggesting BP…