Silvina Ruvinsky
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View article: Validation of a low cost model for training retrocecal laparoscopic appendectomy
Validation of a low cost model for training retrocecal laparoscopic appendectomy Open
View article: Second epidemiological study of pediatric sepsis and septic shock in Argentina (ESSPED-2)
Second epidemiological study of pediatric sepsis and septic shock in Argentina (ESSPED-2) Open
ntroduction. Sepsis is one of the leading causes of pediatric mortality in Argentina. The aim was to describe the epidemiological characteristics of sepsis and septic shock (ESSPED-2 study) in pediatric intensive care units (PICUs) in Arge…
View article: Respiratory syncytial virus disease burden in children and adults from Latin America: a systematic review and meta-analysis
Respiratory syncytial virus disease burden in children and adults from Latin America: a systematic review and meta-analysis Open
Background Respiratory Syncytial Virus (RSV) is a common cause of lower respiratory tract infections (LRTI) and hospitalization worldwide. The impact of RSV in Latin America and the Caribbean (LAC) including expensive treatment options, su…
View article: Full Validation and Application to Clinical Research of a High-Performance Liquid Chromatography Method for the Assessment of Urinary 3-Indoxyl Sulfate in Pediatric Patients with Hematopoietic Stem Cell Transplant
Full Validation and Application to Clinical Research of a High-Performance Liquid Chromatography Method for the Assessment of Urinary 3-Indoxyl Sulfate in Pediatric Patients with Hematopoietic Stem Cell Transplant Open
3-indoxyl sulfate (3-IS) results from a hepatic transformation of indole, a tryptophan degradation product produced by commensal gut bacteria. The metabolite has shown promise as a biomarker of dysbiosis and clinical outcomes following hem…
View article: Economic burden of respiratory syncytial virus disease in Latin America: A systematic review
Economic burden of respiratory syncytial virus disease in Latin America: A systematic review Open
This Systematic Review assesses the economic impact of Respiratory Syncytial Virus (RSV) in Latin America and the Caribbean (LAC) in relation to healthcare resource utilization and associated costs. We searched online databases from Januar…
View article: Invasive pneumococcal disease in Latin America and the Caribbean: Serotype distribution, disease burden, and impact of vaccination. A systematic review and meta-analysis
Invasive pneumococcal disease in Latin America and the Caribbean: Serotype distribution, disease burden, and impact of vaccination. A systematic review and meta-analysis Open
Background Invasive pneumococcal diseases (IPD) are associated with high morbidity, mortality, and health costs worldwide, particularly in Latin America and the Caribbean (LAC). Surveillance about the distribution of serotypes causing IPD …
View article: Nasopharyngeal carriage of Streptococcus pneumoniae in Latin America and the Caribbean: A systematic review and meta-analysis
Nasopharyngeal carriage of Streptococcus pneumoniae in Latin America and the Caribbean: A systematic review and meta-analysis Open
Background Streptococcus pneumoniae is a leading cause of morbidity and mortality globally, causing bacteremic pneumonia, meningitis, sepsis, and other invasive pneumococcal diseases. Evidence supports nasopharyngeal pneumococcal carriage …
View article: Pediatric COVID-19 in Argentina: a comprehensive analysis of disease and economic burden through official data and a systematic literature review
Pediatric COVID-19 in Argentina: a comprehensive analysis of disease and economic burden through official data and a systematic literature review Open
Background Limited data are available on the clinical impact and economic burden of COVID-19 in the pediatric population in Argentina. We aimed to estimate the disease and economic burden of COVID-19 on children and adolescents. Methods We…
View article: Antimicrobial resistance of Streptococcus pneumoniae from invasive pneumococcal diseases in Latin American countries: a systematic review and meta-analysis
Antimicrobial resistance of Streptococcus pneumoniae from invasive pneumococcal diseases in Latin American countries: a systematic review and meta-analysis Open
Background Invasive pneumococcal disease has declined since pneumococcal conjugate vaccine introduction in Latin America and the Caribbean (LAC). However, serotype distribution and antimicrobial resistance patterns have changed. Methods We…
View article: 2800. Carbapenem Resistant <i>Enterobacteriaceae</i> bloodstream infections in children from Latin America & Caribbean region: systematic review and meta-analysis
2800. Carbapenem Resistant <i>Enterobacteriaceae</i> bloodstream infections in children from Latin America & Caribbean region: systematic review and meta-analysis Open
Background Systematic reviews about the burden and use of resource related to Carbapenem Resistant Enterobacteriaceae bloodstream infections (CRE-BI) in children from Latin America and Caribbean (LAC ) is scarce. Methods Objectives To anal…
View article: Validation of a low-cost model for training laparoscopic ovary-sparing surgery (LOSS) in ovarian mature teratomas
Validation of a low-cost model for training laparoscopic ovary-sparing surgery (LOSS) in ovarian mature teratomas Open
Background: Mature ovarian teratoma is the most common ovarian neoplasm in pediatrics. Laparoscopic ovary sparing surgery (LOSS) is effective and safe. Due to the expansion of this technique in recent years, education-based surgical simula…
View article: COVID-19 in immunocompromised children: comparison of SARS-CoV-2 viral load dynamics between the first and third waves
COVID-19 in immunocompromised children: comparison of SARS-CoV-2 viral load dynamics between the first and third waves Open
View article: Recomendaciones para el cuidado, prevención de infecciones y quimioprofilaxis en los errores innatos de la inmunidad
Recomendaciones para el cuidado, prevención de infecciones y quimioprofilaxis en los errores innatos de la inmunidad Open
Inborn errors of immunity, previously named primary immunodeficiency are a heterogeneous group of genetic defects of different components of the immune system. Patients present high susceptibility to an only or several microorganisms, deve…
View article: Comparative effectiveness of telesimulation versus standard simulation for pediatric Minimally Invasive Surgery (MIS) essential skills training
Comparative effectiveness of telesimulation versus standard simulation for pediatric Minimally Invasive Surgery (MIS) essential skills training Open
View article: Comparison of SARS-CoV-2 viral load in asymptomatic and symptomatic children attended in a referral public pediatric hospital in Argentina
Comparison of SARS-CoV-2 viral load in asymptomatic and symptomatic children attended in a referral public pediatric hospital in Argentina Open
At present, different reports have shown that children reach similar SARS-CoV-2 viral load (VL) levels compared to adults; however, the impact of VL on children remains ambiguous when asymptomatic versus symptomatic cases are compared. Thu…
View article: Efectividad de un programa de reducción de bacteriemias relacionadas con catéter venoso central en una unidad cardiovascular pediátrica
Efectividad de un programa de reducción de bacteriemias relacionadas con catéter venoso central en una unidad cardiovascular pediátrica Open
Efectividad de un programa de reducción de bacteriemias relacionadas con catéter venoso central en una
View article: Effectiveness of a program for the reduction of central venous catheter-related bacteremias in a Pediatric Cardiovascular Unit
Effectiveness of a program for the reduction of central venous catheter-related bacteremias in a Pediatric Cardiovascular Unit Open
The program was effective; the rate of CVC-related bacteremias in the PCICU showed a progressive, significant reduction.
View article: Carbapenem-resistant Enterobacteriaceae bloodstream infections: A case-control study from a pediatric referral hospital in Argentina
Carbapenem-resistant Enterobacteriaceae bloodstream infections: A case-control study from a pediatric referral hospital in Argentina Open
Background Antibiotic-resistant gram-negative bloodstream infections (BSI) remain a leading cause morbidity and mortality in pediatric patients with a high impact on the public health system. Data in resource-limited countries, including t…
View article: Multisystem Inflammatory Syndrome Temporally Related to COVID-19 in Children From Latin America and the Caribbean Region: A Systematic Review With a Meta-Analysis of Data From Regional Surveillance Systems
Multisystem Inflammatory Syndrome Temporally Related to COVID-19 in Children From Latin America and the Caribbean Region: A Systematic Review With a Meta-Analysis of Data From Regional Surveillance Systems Open
Background With the emergence of the COVID-19 pandemic, increasing numbers of cases of the multisystem inflammatory syndrome in children (MIS-C) have been reported worldwide; however, it is unclear whether this syndrome has a differential …
View article: Latin American Consensus on the Management of Sepsis in Children: Sociedad Latinoamericana de Cuidados Intensivos Pediátricos [Latin American Pediatric Intensive Care Society] (SLACIP) Task Force: Executive Summary
Latin American Consensus on the Management of Sepsis in Children: Sociedad Latinoamericana de Cuidados Intensivos Pediátricos [Latin American Pediatric Intensive Care Society] (SLACIP) Task Force: Executive Summary Open
Objective: The aim of this study was to develop evidence-based recommendations for the diagnosis and treatment of sepsis in children in low- and middle-income countries (LMICs), more specifically in Latin America. Design: A panel was forme…
View article: Case Report: Hyperinflammatory Status in an Immunocompromised Child With a Highly Sustained Viral Load of SARS-CoV-2
Case Report: Hyperinflammatory Status in an Immunocompromised Child With a Highly Sustained Viral Load of SARS-CoV-2 Open
Coronavirus disease 2019 (COVID-19) is spreading throughout the world. Limited data are available for the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load (VL) in immunocompromised pediatric patients. Her…
View article: Experiencia con el uso de daptomicina en un hospital pediátrico de alta complejidad
Experiencia con el uso de daptomicina en un hospital pediátrico de alta complejidad Open
Daptomycin demonstrated a favorable efficacy and safety in this pediatric population.
View article: Taller de priorización de intervenciones para el control del mosquito Aedes aegypti en Latinoamérica y el Caribe: diálogo de políticas
Taller de priorización de intervenciones para el control del mosquito Aedes aegypti en Latinoamérica y el Caribe: diálogo de políticas Open
This article presents the results of a dialogue between decision-makers and experts in Latin America and the Caribbean on priority-setting for interventions and studies on Aedes aegypti control. The article is part of a project that includ…
View article: Interventions for the control of <i>Aedes aegypti</i> in Latin America and the Caribbean: systematic review and meta‐analysis
Interventions for the control of <i>Aedes aegypti</i> in Latin America and the Caribbean: systematic review and meta‐analysis Open
Objective To determine the effectiveness and degree of implementation of interventions for the control of Aedes aegypti in Latin America and the Caribbean ( LAC ) as reported in scientific literature. Methods We searched MEDLINE , EMBASE ,…
View article: Experiencias, barreras y facilitadores en la implementación de intervenciones de control del Aedes aegypti en América Latina y Caribe: estudio cualitativo
Experiencias, barreras y facilitadores en la implementación de intervenciones de control del Aedes aegypti en América Latina y Caribe: estudio cualitativo Open
El objetivo fue describir experiencias, barreras y facilitadores en la implementación de intervenciones de control del Aedes aegypti en América Latina y Caribe. Fue realizado un abordaje cualitativo con entrevistas en profundidad semiestru…
View article: Workshop for priority-setting in Aedes aegypti control interventions in Latin America and the Caribbean: a policy dialogue
Workshop for priority-setting in Aedes aegypti control interventions in Latin America and the Caribbean: a policy dialogue Open
This article presents the results of a dialogue between decision-makers and experts in Latin America and the Caribbean on priority-setting for interventions and studies on Aedes aegypti control. The article is part of a project that includ…
View article: Workshop for priority-setting in Aedes aegypti control interventions in Latin America and the Caribbean: a policy dialogue
Workshop for priority-setting in Aedes aegypti control interventions in Latin America and the Caribbean: a policy dialogue Open
This article presents the results of a dialogue between decision-makers and experts in Latin America and the Caribbean on priority-setting for interventions and studies on Aedes aegypti control. The article is part of a project that includ…
View article: Interventions for the control of Aedes Aegypti in Latin America and the Caribbean: Systematic review and meta-analysis
Interventions for the control of Aedes Aegypti in Latin America and the Caribbean: Systematic review and meta-analysis Open
Background: Aedes aegypti is the vector responsible for spreading zika, dengue, chikungunya and yellow fever. In recent years, the burden of these diseases has increased in Latin America. Our objective was to determine the effectiveness of…
View article: Barriers and facilitators for the implementation of interventions to control Aedes aegypti in Latin America and the Caribbean: Qualitative study with in-depth interviews
Barriers and facilitators for the implementation of interventions to control Aedes aegypti in Latin America and the Caribbean: Qualitative study with in-depth interviews Open
Background: The Aedes aegypti (AA) mosquito is the main vector transmitting Dengue, Chikungunya, Zika and Yellow Fever. In Latin America and the Caribbean (LA&C) the incidence and severity of Dengue have increased rapidly in recent years. …
View article: Acute arterial embolism as the clinical presentation of a disseminated hydatidosis: case report
Acute arterial embolism as the clinical presentation of a disseminated hydatidosis: case report Open
Hydatidosis is a parasitic infection caused by the Echinococcus granulosus larvae, transmitted by the ingestion of infected food, characterized by the formation of cysts in vital organs. In Argentina, the disease is spread throughout the t…