Silvio Weging
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View article: Spaceflight alters host-gut microbiota interactions
Spaceflight alters host-gut microbiota interactions Open
The ISS rodent habitat has provided crucial insights into the impact of spaceflight on mammals, inducing symptoms characteristic of liver disease, insulin resistance, osteopenia, and myopathy. Although these physiological responses can inv…
View article: Spaceflight alters host-gut microbiota interactions
Spaceflight alters host-gut microbiota interactions Open
The rodent habitat on the International Space Station has provided crucial insights into the impact of spaceflight on mammals, inducing symptoms characteristic of liver disease, insulin resistance, osteopenia, and myopathy. Although these …
View article: Spaceflight alters host-gut microbiota interactions
Spaceflight alters host-gut microbiota interactions Open
The rodent habitat on the International Space Station has provided crucial insights into the impact of spaceflight on mammals, including observation of symptoms characteristic of liver disease, insulin resistance, osteopenia and myopathy. …
View article: Enhancing European capabilities for application of multi-omics studies in biology and biomedicine space research
Enhancing European capabilities for application of multi-omics studies in biology and biomedicine space research Open
Following on from the NASA twins' study, there has been a tremendous interest in the use of omics techniques in spaceflight. Individual space agencies, NASA's GeneLab, JAXA's ibSLS, and the ESA-funded Space Omics Topical Team and the Inter…
View article: NASA GeneLab RNA-seq consensus pipeline: Standardized processing of short-read RNA-seq data
NASA GeneLab RNA-seq consensus pipeline: Standardized processing of short-read RNA-seq data Open
With the development of transcriptomic technologies, we are able to quantify precise changes in gene expression profiles from astronauts and other organisms exposed to spaceflight. Members of NASA GeneLab and GeneLab-associated analysis wo…
View article: Taxonomic analysis of metagenomic data with kASA
Taxonomic analysis of metagenomic data with kASA Open
The taxonomic analysis of sequencing data has become important in many areas of life sciences. However, currently available tools for that purpose either consume large amounts of RAM or yield insufficient quality and robustness. Here, we p…
View article: NASA GeneLab RNA-Seq Consensus Pipeline: Standardized Processing of Short-Read RNA-Seq Data
NASA GeneLab RNA-Seq Consensus Pipeline: Standardized Processing of Short-Read RNA-Seq Data Open
Summary With the development of transcriptomic technologies, we are able to quantify precise changes in gene expression profiles from astronauts and other organisms exposed to spaceflight. Members of NASA GeneLab and GeneLab-associated ana…
View article: kASA: Taxonomic Analysis of Metagenomic Data on a Notebook
kASA: Taxonomic Analysis of Metagenomic Data on a Notebook Open
The taxonomic analysis of sequencing data has become important in many areas of life sciences. However, currently available software tools for that purpose either consume large amounts of RAM or yield an insufficient quality of the results…
View article: Data, truth sets and content files used for the comparative study in "kASA: Taxonomic Analysis of Metagenomic Data on a Notebook"
Data, truth sets and content files used for the comparative study in "kASA: Taxonomic Analysis of Metagenomic Data on a Notebook" Open
Content files for both databases as described in the publication of kASA as well as datasets and truth sets used for the comparative analysis as sanity check which is mentioned in the first part of "Results".
View article: Elevated virulence of an emerging viral genotype as a driver of honeybee loss
Elevated virulence of an emerging viral genotype as a driver of honeybee loss Open
Emerging infectious diseases (EIDs) have contributed significantly to the current biodiversity crisis, leading to widespread epidemics and population loss. Owing to genetic variation in pathogen virulence, a complete understanding of speci…