Silviu Ionel Dumitrescu
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View article: Biomolecular Interaction, Molecular Docking, Antimicrobial, Antioxidant, Antitumor, Cell Cycle Analysis, and Annexin V/PI Assay Efficiency of Some Co (II), Cu (II), Mn (II), Ni (II), Pd (II), and Pt (II) Complexes With a Halogenated Bidentate Schiff Base
Biomolecular Interaction, Molecular Docking, Antimicrobial, Antioxidant, Antitumor, Cell Cycle Analysis, and Annexin V/PI Assay Efficiency of Some Co (II), Cu (II), Mn (II), Ni (II), Pd (II), and Pt (II) Complexes With a Halogenated Bidentate Schiff Base Open
This study addresses the bioactivity evaluation of some complexes with a halogenated Schiff base ( HL ). The investigation of the biological potential was first performed in silico, through molecular docking studies. Thus, binding affiniti…
View article: Proposed NT-ProBNP Threshold for Predicting 2-Year Heart Failure Mortality and Implications for Long-Term Community Follow-Up
Proposed NT-ProBNP Threshold for Predicting 2-Year Heart Failure Mortality and Implications for Long-Term Community Follow-Up Open
Background/Objectives: Pre-discharge NT-proBNP levels may serve as a helpful tool in the algorithm of assessing the long-term risk of mortality after a hospitalization for symptomatic heart failure (HF). The goals were: (a) to identify a c…
View article: Remote Monitoring of Patients with Heart Failure: Characteristics of Effective Programs and Implementation Strategies
Remote Monitoring of Patients with Heart Failure: Characteristics of Effective Programs and Implementation Strategies Open
The post-pandemic research targeting RM of patients with HF presents more homogenous results to support this type of intervention, as compared to the heterogeneity of the pre-pandemic research.
View article: Secondary Prevention After Acute Coronary Syndromes in Women: Tailored Management and Cardiac Rehabilitation
Secondary Prevention After Acute Coronary Syndromes in Women: Tailored Management and Cardiac Rehabilitation Open
Secondary prevention after acute coronary syndromes is the key strategy to reduce the residual cardiovascular disease risk. A tailored assessment is necessary to suggest the best management and treatment for patients. Sex and gender differ…
View article: LBBB is a totally a non-homogenous concept: defining 4 phenotypes of response to CRT in a highly experienced center
LBBB is a totally a non-homogenous concept: defining 4 phenotypes of response to CRT in a highly experienced center Open
Introduction Cardiac resynchronization (CRT) is a well-established technique used to treat significant HF patients who associate LBBB and severe LV dysfunction. CRT indications refer to a certain clinical profile but not to the underlying …
View article: The real-world anti-inflammatory effect of SGLT2i in patients with chronic heart failure
The real-world anti-inflammatory effect of SGLT2i in patients with chronic heart failure Open
Inflammation plays a major role in the etiology of chronic heart failure and in inducing the progression to end-stage heart failure. This chronic inflammation, which accompanies heart failure, is not only local but also systemic and is usu…
View article: The Role of Multimodal Imaging in a Case if Infective Endocarditis . . . with Surprises and Happy Ending
The Role of Multimodal Imaging in a Case if Infective Endocarditis . . . with Surprises and Happy Ending Open
Infective endocarditis, a potentially fatal condition and a serious public health problem can be difficult to diagnose due to non-specific symptoms. Thus, the multidisciplinary approach to this pathology by the Endocarditis Team is essenti…
View article: c ANCA Antibodies and Infective Endocarditis -Friends Or Foes?
c ANCA Antibodies and Infective Endocarditis -Friends Or Foes? Open
The differential diagnosis between granulomatosis with polyangiitis (GPA) and infective endocarditis (IE) is crucial. Both diseases show clinical similarities and serologic c-ANCA overlap. We present the case of a 45-year-old patient with …
View article: Guideline-Optimised Treatment in Heart Failure—Do Higher Doses Reduce Systemic Inflammation More Significantly?
Guideline-Optimised Treatment in Heart Failure—Do Higher Doses Reduce Systemic Inflammation More Significantly? Open
Background: Chronic inflammation is a constant phenomenon which accompanies the heart failure pathophysiology. In all phenotypes of heart failure, irrespective of the ejection fraction, there is a permanent low-grade activation and synthes…
View article: Cardiac Adaptation in Performance Athletes: A Systematic Review
Cardiac Adaptation in Performance Athletes: A Systematic Review Open
Athlete’s heart is characterised by structural, functional, and electrical remodelling. During an exercise session, the heart increases the use of oxygen, which is associated with decreased vascular resistance in the lungs’ circulation. Le…
View article: Inflammation in Heart Failure—Future Perspectives
Inflammation in Heart Failure—Future Perspectives Open
Chronic heart failure is a terminal point of a vast majority of cardiac or extracardiac causes affecting around 1–2% of the global population and more than 10% of the people above the age of 65. Inflammation is persistently associated with…
View article: Metal and Metal Oxide Nanoparticle Incorporation in Polyurethane Foams: A Solution for Future Antimicrobial Materials?
Metal and Metal Oxide Nanoparticle Incorporation in Polyurethane Foams: A Solution for Future Antimicrobial Materials? Open
With the technological developments witnessed in recent decades, nanotechnology and nanomaterials have found uses in several common applications and products we encounter daily. On the other hand, polyurethane (PU) foams represent an extre…
View article: Cardiotoxicity of Chemotherapy in Lynch Syndrome – A Literature Review
Cardiotoxicity of Chemotherapy in Lynch Syndrome – A Literature Review Open
"Chemotherapy is an important treatment in oncological disease, with a vast number of side effects. The cardiotoxicity of several chemotherapeutic agents and appropriate risk stratification and patient follow-up must be ensured by a multid…
View article: Considerations on Prevention and Protections Measures Against Occupational Risks
Considerations on Prevention and Protections Measures Against Occupational Risks Open
A general trend, manifested at the European and international level, is to promote the use of scientific methods in preventive activity, both in terms of the design of work security measures, and the motivation of employers for the applica…
View article: Essential in Genetic Etiology of Congenital Heart Diseases
Essential in Genetic Etiology of Congenital Heart Diseases Open
Congenital heart disease (CHD) represent another unsolved problem of the present, although new techniques of exploration like fluorescence in situ hybridization (FISH), high resolution array-comparative genomic hybridization (array-CGH), s…