Simin Farokhi
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View article: Chronic Rhinosinusitis with Nasal Polyps: Window of Immunologic Responses and Horizon of Biological Therapies
Chronic Rhinosinusitis with Nasal Polyps: Window of Immunologic Responses and Horizon of Biological Therapies Open
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a multifaceted inflammatory disorder characterized by distinct immunopathogenic entities, including type 2 inflammation mediated by cytokines such as interleukin-4 (IL-4), IL-5, and IL-1…
View article: The diagnostic accuracy of MRI radiomics in axillary lymph node metastasis prediction: a systematic review and meta-analysis
The diagnostic accuracy of MRI radiomics in axillary lymph node metastasis prediction: a systematic review and meta-analysis Open
Background: Breast cancer is the most prevalent malignancy in women and a leading cause of mortality. Accurate assessment of axillary lymph node metastasis (LNM) is critical for breast cancer management. Exploring non-invasive methods such…
View article: Exploring two tumor treatment strategies: effectiveness of ribosome inactivating proteins and mesenchymal stem cells/MSC derived extracellular vesicles in cancer treatment
Exploring two tumor treatment strategies: effectiveness of ribosome inactivating proteins and mesenchymal stem cells/MSC derived extracellular vesicles in cancer treatment Open
Cancer is a complex and heterogeneous disease that often requires multifaceted treatment strategies to achieve optimal therapeutic outcomes. Given the limitations of single-agent therapies, particularly in the face of intricate biological …
View article: Assessing the recurrence rate in locally advanced Luminal A patients compared to triple-negative patients in Shahid Rahimi Hospital Khorramabad in 2022: a cross-sectional study
Assessing the recurrence rate in locally advanced Luminal A patients compared to triple-negative patients in Shahid Rahimi Hospital Khorramabad in 2022: a cross-sectional study Open
Background: Breast cancer is one of the most common causes of cancer death in women both globally and in Iran. Although medical breakthroughs have improved its prognosis, different characteristics can vary locally, especially in understudi…
View article: Hydrogel-based nanoparticles: revolutionizing brain tumor treatment and paving the way for future innovations
Hydrogel-based nanoparticles: revolutionizing brain tumor treatment and paving the way for future innovations Open
View article: Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights
Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights Open
Mortality and morbidity from cardiovascular diseases are common worldwide. In order to improve survival and quality of life for this patient population, extensive efforts are being made to establish effective therapeutic modalities. New tr…
View article: New perspectives on arteriosclerosis treatment using nanoparticles and mesenchymal stem cells
New perspectives on arteriosclerosis treatment using nanoparticles and mesenchymal stem cells Open
Arteriosclerosis (AS) presents a significant global health challenge, demanding innovative therapeutic strategies. This review explores the potential of nanoparticles (NPs) and mesenchymal stem cells (MSCs) as promising modalities for trea…
View article: Advancements in tissue engineering for cardiovascular health: a biomedical engineering perspective
Advancements in tissue engineering for cardiovascular health: a biomedical engineering perspective Open
Myocardial infarction (MI) stands as a prominent contributor to global cardiovascular disease (CVD) mortality rates. Acute MI (AMI) can result in the loss of a large number of cardiomyocytes (CMs), which the adult heart struggles to replen…
View article: Regenerative potential of mesenchymal stromal cells in wound healing: unveiling the influence of normoxic and hypoxic environments
Regenerative potential of mesenchymal stromal cells in wound healing: unveiling the influence of normoxic and hypoxic environments Open
The innate and adaptive immune systems rely on the skin for various purposes, serving as the primary defense against harmful environmental elements. However, skin lesions may lead to undesirable consequences such as scarring, accelerated s…
View article: Double-edged sword of JAK/STAT signaling pathway in viral infections: novel insights into virotherapy
Double-edged sword of JAK/STAT signaling pathway in viral infections: novel insights into virotherapy Open
View article: A Novel NALCN Homozygote Variant in Non-related Infants with IHPRF1 Syndrome: A Report of 2 Cases
A Novel NALCN Homozygote Variant in Non-related Infants with IHPRF1 Syndrome: A Report of 2 Cases Open
Introduction: Sodium leak channel, non-selective (NALCN) is an ion channel with an important function in neuronal excitability. The activity of NALCN is essential in the balance of rhythmic behaviors. Infantile hypotonia with psychomotor r…