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View article: Comparing Percutaneous Kyphoplasty Outcomes in Very Severe Osteoporotic Vertebral Compression Fractures Across Distinct Spinal Segments: Upper/Middle Thoracic versus Thoracolumbar
Comparing Percutaneous Kyphoplasty Outcomes in Very Severe Osteoporotic Vertebral Compression Fractures Across Distinct Spinal Segments: Upper/Middle Thoracic versus Thoracolumbar Open
PKP provides significant pain relief and functional improvement in vsOVCF, regardless of the lesion's location. However, thoraco/lumbar vsOVCF demonstrate substantially higher risk of augmented vertebral recollapse after PKP.
View article: Spatiotemporal variability and controls of CH4 and CO2 emissions in an alpine reservoir: insights from the Liujiaxia system
Spatiotemporal variability and controls of CH4 and CO2 emissions in an alpine reservoir: insights from the Liujiaxia system Open
Alpine reservoirs represent critical but poorly quantified sources of greenhouse gas (GHG) emissions from inland waters. This study examines spatiotemporal variations and drivers of methane (CH4) and carbon dioxide (CO2) fluxes in the Liuj…
View article: Exhaled volatile organic compounds as novel biomarkers for early detection of COPD, asthma, and PRISm: a cross-sectional study
Exhaled volatile organic compounds as novel biomarkers for early detection of COPD, asthma, and PRISm: a cross-sectional study Open
View article: Disruption of <scp><i>Ephb1</i></scp> causes reduced hypothalamic <scp>CRH</scp> and <scp>TRH</scp> expression and obesity in mice
Disruption of <span><i>Ephb1</i></span> causes reduced hypothalamic <span>CRH</span> and <span>TRH</span> expression and obesity in mice Open
Objective Ephrin type‐B receptor 1 (EphB1) is a receptor tyrosine kinase involved in axon guidance, synaptic plasticity, and tumorigenesis. However, the role of EphB1 in metabolic regulation and obesity remains poorly understood. This stud…
View article: Population Pharmacokinetic Modeling of IMP7068 in Patients with Advanced Solid Tumors
Population Pharmacokinetic Modeling of IMP7068 in Patients with Advanced Solid Tumors Open
View article: Exposure-Response Analysis for Hepatotoxicity of Rivoceranib Monotherapy and in Combination with Camrelizumab in Patients with Various Cancers, Including Advanced Hepatocellular Carcinoma
Exposure-Response Analysis for Hepatotoxicity of Rivoceranib Monotherapy and in Combination with Camrelizumab in Patients with Various Cancers, Including Advanced Hepatocellular Carcinoma Open
View article: Amide proton transfer (APT) and magnetization transfer (MT) in predicting short-term therapeutic outcome in nasopharyngeal carcinoma after chemoradiotherapy: a feasibility study of three-dimensional chemical exchange saturation transfer (CEST) MRI
Amide proton transfer (APT) and magnetization transfer (MT) in predicting short-term therapeutic outcome in nasopharyngeal carcinoma after chemoradiotherapy: a feasibility study of three-dimensional chemical exchange saturation transfer (CEST) MRI Open
View article: Co-engagement of TIGIT<sup>+</sup>immune cells to PD-L1<sup>+</sup>tumours by a bispecific antibody potentiates T-cell response and tumour control
Co-engagement of TIGIT<sup>+</sup>immune cells to PD-L1<sup>+</sup>tumours by a bispecific antibody potentiates T-cell response and tumour control Open
Co-targeting PD-1/PD-L1 and TIGIT/CD226 is being pursued to broaden the efficacy of current immunotherapy. Here we demonstrate that a bispecific antibody (BsAb) targeting PD-L1 and TIGIT, HB0036, shows major advantages over the combination…
View article: Progesterone is an Inducement of Heritable Pulmonary Arterial Hypertension with BMPR2 Mutation
Progesterone is an Inducement of Heritable Pulmonary Arterial Hypertension with BMPR2 Mutation Open
Background Bone morphogenetic protein type II receptor (BMPR2) gene mutation accounts for 80% of patients with heritable pulmonary artery hypertension (HPAH), and female mutation carriers have significantly higher penetrance rate than male…
View article: Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype
Development and validation of MRI-based model for the preoperative prediction of macrotrabecular hepatocellular carcinoma subtype Open
Background Macrotrabecular hepatocellular carcinoma (MTHCC) has a poor prognosis and is difficult to diagnose preoperatively. The purpose is to build and validate MRI-based models to predict the MTHCC subtype. Methods Two hundred eight pat…
View article: Changes of Women's Status from the Evolution of Dunhuang Murals—Taking Images of Donors and Feitian Legends as Examples
Changes of Women's Status from the Evolution of Dunhuang Murals—Taking Images of Donors and Feitian Legends as Examples Open
It is well-known that social phenomena can be reflected in art. In the past research time, there have been some research results about the Dunhuang murals and gender equality, respectively. However, there is no such one as combining the tw…
View article: Comparing the clinical utility of single-shot, readout-segmented and zoomit echo-planar imaging in diffusion-weighted imaging of the kidney at 3 T
Comparing the clinical utility of single-shot, readout-segmented and zoomit echo-planar imaging in diffusion-weighted imaging of the kidney at 3 T Open
View article: Population Pharmacokinetic Modeling and Simulation of TQ-B3101 to Inform Dosing in Pediatric Patients With Solid Tumors
Population Pharmacokinetic Modeling and Simulation of TQ-B3101 to Inform Dosing in Pediatric Patients With Solid Tumors Open
Background: TQ-B3101 is a novel kinase inhibitor currently in development for the treatment of advanced malignant solid tumor and relapsed or refractory ALK-positive anaplastic large cell lymphoma. Methods: A population pharmacokinetic mod…
View article: Case Report: Respiratory Management With a 47-Day ECMO Support for a Critical Patient With COVID-19
Case Report: Respiratory Management With a 47-Day ECMO Support for a Critical Patient With COVID-19 Open
This paper reports a complete case of severe acute respiratory distress syndrome (ARDS) caused by coronavirus disease 2019 (COVID-19), who presented with rapid deterioration of oxygenation during hospitalization despite escalating high-flo…
View article: The application of texture quantification in hepatocellular carcinoma using CT and MRI: a review of perspectives and challenges
The application of texture quantification in hepatocellular carcinoma using CT and MRI: a review of perspectives and challenges Open
View article: Comparing Chinese children and adults with RT-PCR positive COVID-19: A systematic review
Comparing Chinese children and adults with RT-PCR positive COVID-19: A systematic review Open
View article: COVID-19: Children Comparison with Adults Based on the Latest Data
COVID-19: Children Comparison with Adults Based on the Latest Data Open
View article: Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders
Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders Open
Rasal2 promotes adipogenesis, which may critically contribute to its role in the development of obesity and related metabolic disorders and may do so by repressing Ras activity in an ERK-independent manner.