Simin Zhao
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View article: Cathepsin B in human peripheral blood lymphocytes as a peripheral biomarker for cardiac hypertrophy
Cathepsin B in human peripheral blood lymphocytes as a peripheral biomarker for cardiac hypertrophy Open
Previous studies have demonstrated that cathepsin B is up-regulated in the myocardium of both mice and humans with pathological cardiac hypertrophy. However, it remains unknown whether cathepsin B is detectable in human peripheral blood ly…
View article: Integrating stoichiometry and chain architecture for accurate copolymer property prediction
Integrating stoichiometry and chain architecture for accurate copolymer property prediction Open
Copolymers' diverse properties are influenced by monomer type, stoichiometry, and chain architecture, making prediction challenging. Traditional machine learning models struggle to capture these complexities. This study introduces Co-MPNN,…
View article: Developing a Rate Law for Ce(III) Oxidation by Manganese Oxides
Developing a Rate Law for Ce(III) Oxidation by Manganese Oxides Open
Rare earth elements (REEs) are critical minerals that are indispensable for clean energy technologies. Understanding REE occurrence and transport in natural environments is important for the prediction and identification of REE resources. …
View article: Rhizosphere bacterial community confers drought tolerance to Astragalus mongholicus
Rhizosphere bacterial community confers drought tolerance to Astragalus mongholicus Open
Drought stress significantly inhibits the growth of Astragalus mongholicus, leading to reduced biomass, decreased photosynthetic efficiency, and exacerbated oxidative damage. In our study, the accumulation of saponins and flavonoids in Ast…
View article: The mediating role of anxiety in poor sleep quality and passive coping among adolescents
The mediating role of anxiety in poor sleep quality and passive coping among adolescents Open
Background The increasing prevalence of poor sleep quality in children and adolescents highlights the essential role of quality sleep in promoting growth and development. Coping styles are associated with cognitive and behavioral adaptatio…
View article: MCM8 interacts with DDX5 to promote R-loop resolution
MCM8 interacts with DDX5 to promote R-loop resolution Open
MCM8 has emerged as a core gene in reproductive aging and is crucial for meiotic homologous recombination repair. It also safeguards genome stability by coordinating the replication stress response during mitosis, but its function in mitot…
View article: Organic Ligand-Mediated Dissolution and Fractionation of Rare-Earth Elements (REEs) from Carbonate and Phosphate Minerals
Organic Ligand-Mediated Dissolution and Fractionation of Rare-Earth Elements (REEs) from Carbonate and Phosphate Minerals Open
Global efforts to build a net-zero economy and the irreplaceable roles of rare-earth elements (REEs) in low-carbon technologies urge the understanding of REE occurrence in natural deposits, discovery of alternative REE resources, and devel…
View article: Moho Inversion by Gravity Anomalies in the South China Sea: Updates and Improved Iteration of the Parker‐Oldenburg Algorithm
Moho Inversion by Gravity Anomalies in the South China Sea: Updates and Improved Iteration of the Parker‐Oldenburg Algorithm Open
The Moho is the interface between crust and mantle, and accurate location of the Moho is important for both resource exploration and deep earth condition and structural change investigations. The theory of the traditional Parker‐Oldenburg …
View article: FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells
FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells Open
Background The maintenance of genome stability in primordial germ cells (PGCs) is crucial for the faithful transmission of genetic information and the establishment of reproductive reserve. Numerous studies in recent decades have linked th…
View article: Characteristics of Chaotic Weak Reflection in Carbonate Fracture–Cavity Reservoirs: A Case Study of Ordovician Reservoirs in Block 10 of the Tahe Oilfield, Tarim Basin, China
Characteristics of Chaotic Weak Reflection in Carbonate Fracture–Cavity Reservoirs: A Case Study of Ordovician Reservoirs in Block 10 of the Tahe Oilfield, Tarim Basin, China Open
The identification of carbonate reservoirs is a critical task in oil and gas exploration. Chaotic weak reflection is an important type of reflection characteristic in carbonate reservoirs. Widespread distribution of chaotic weak reflection…
View article: Green Approach for Rare Earth Element (REE) Recovery from Coal Fly Ash
Green Approach for Rare Earth Element (REE) Recovery from Coal Fly Ash Open
Due to the growing demands of rare earth elements (REEs) and the vulnerability of REEs to potential supply disruption, there have been increasing interests in recovering REEs from waste streams such as coal fly ash (CFA). Meanwhile, CFA as…
View article: UBE2T resolves transcription-replication conflicts and protects common fragile sites in primordial germ cells
UBE2T resolves transcription-replication conflicts and protects common fragile sites in primordial germ cells Open
View article: TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis
TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis Open
The transcription factor p63 guards genome integrity in the female germline, and its mutations have been reported in patients with premature ovarian insufficiency (POI). However, the precise contribution of the TP63 gene to the pathogenesi…
View article: DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development
DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development Open
When DNA interstrand crosslink lesions occur, a core complex of Fanconi anemia proteins promotes the ubiquitination of FANCD2 and FANCI, which recruit downstream factors to repair the lesion. However, FANCD2 maintains genome stability not …
View article: Additional file 9 of FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells
Additional file 9 of FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells Open
Additional file 9. Individual data values.
View article: Moho Inversion by Gravity Anomalies in the South China Sea: Updates and Improved Iteration of the Parker-Oldenburg Algorithm.
Moho Inversion by Gravity Anomalies in the South China Sea: Updates and Improved Iteration of the Parker-Oldenburg Algorithm. Open
The Moho is the interface between crust and mantle, and accurate location of the Moho is important for both resource exploration and deep earth condition and structural change investigations. The Parker-Oldenburg (P-O) method, is simple an…
View article: Transcription–replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability
Transcription–replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability Open
Preserving a high degree of genome integrity and stability in germ cells is of utmost importance for reproduction and species propagation. However, the regulatory mechanisms of maintaining genome stability in the developing primordial germ…
View article: Lignin-enhanced reduction of structural Fe(III) in nontronite: Dual roles of lignin as electron shuttle and donor
Lignin-enhanced reduction of structural Fe(III) in nontronite: Dual roles of lignin as electron shuttle and donor Open
View article: Fe Redox Cycling Revealed by Ligand-Promoted Microbial Fe(II) Oxidation in Clay Mineral
Fe Redox Cycling Revealed by Ligand-Promoted Microbial Fe(II) Oxidation in Clay Mineral Open
Nitrate-dependent Fe(II) oxidation is important for environmental processes.Past research has focused on microbial oxidation of either aqueous Fe 2+ or solidphase Fe(II), however, the effects of organic ligands are not well understood.The …