Siming Yang
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View article: Association between body roundness index and hearing loss in the United States population: A cross-sectional study
Association between body roundness index and hearing loss in the United States population: A cross-sectional study Open
Hearing loss represents a significant public health concern, with obesity increasingly recognized as a potential risk factor. The body roundness index (BRI) is a novel anthropometric measure that more accurately reflects body fat distribut…
View article: P-591 Per- and Polyfluoroalkyl Substances Serum Concentrations and Polycystic Ovary Syndrome among Women Attending a Fertility Clinic
P-591 Per- and Polyfluoroalkyl Substances Serum Concentrations and Polycystic Ovary Syndrome among Women Attending a Fertility Clinic Open
Study question What is the association between serum per- and poly-fluoroalkyl substances (PFAS) concentrations and polycystic ovary syndrome (PCOS) risk in populations with low-level PFAS exposure. Summary answer Higher serum concentratio…
View article: Ginsenoside Rh4 Improves Hepatic Lipid Metabolism and Inflammation in a Model of NAFLD by Targeting the Gut Liver Axis and Modulating the FXR Signaling Pathway
Ginsenoside Rh4 Improves Hepatic Lipid Metabolism and Inflammation in a Model of NAFLD by Targeting the Gut Liver Axis and Modulating the FXR Signaling Pathway Open
Non-alcoholic fatty liver disease (NAFLD) is a series of disorders of liver metabolism caused by the accumulation of lipids in the liver, which is considered the main cause of hepatocellular carcinoma. Our previous study demonstrated the p…
View article: Transplantation of Umbilical Cord-Derived Mesenchymal Stem Cells Attenuates Surgical Wound-Induced Blood-Brain Barrier Dysfunction in Mice
Transplantation of Umbilical Cord-Derived Mesenchymal Stem Cells Attenuates Surgical Wound-Induced Blood-Brain Barrier Dysfunction in Mice Open
Blood-brain barrier (BBB) is the most important component of central nervous system (CNS) to keep toxins and pathogens from CNS. Although our studies demonstrated that using interleukin-6 antibodies (IL-6-AB) reversed the increased permeab…
View article: Therapeutic effects of mesenchymal stem cells and their derivatives in common skin inflammatory diseases: Atopic dermatitis and psoriasis
Therapeutic effects of mesenchymal stem cells and their derivatives in common skin inflammatory diseases: Atopic dermatitis and psoriasis Open
Chronic skin inflammatory diseases including atopic dermatitis (AD) and psoriasis have been considered uncontrolled inflammatory responses, which have usually troubled patients around the world. Moreover, the recent method to treat AD and …
View article: Identification and validation of signature for prognosis and immune microenvironment in gastric cancer based on m6A demethylase ALKBH5
Identification and validation of signature for prognosis and immune microenvironment in gastric cancer based on m6A demethylase ALKBH5 Open
Background N6-methyladenosine (m6A) RNA regulators play important roles in cancers, but their functions and mechanism have not been demonstrated clearly in gastric cancer (GC). Methods In this study, the GC samples with clinical informatio…
View article: New insight into neurological degeneration: Inflammatory cytokines and blood–brain barrier
New insight into neurological degeneration: Inflammatory cytokines and blood–brain barrier Open
Neurological degeneration after neuroinflammation, such as that resulting from Alzheimer’s disease (AD), stroke, multiple sclerosis (MS), and post-traumatic brain injury (TBI), is typically associated with high mortality and morbidity and …
View article: Identification of Prognosis Signature and Analysis of the Immune Microenvironment in Gastric Cancer Based on ALKBH5
Identification of Prognosis Signature and Analysis of the Immune Microenvironment in Gastric Cancer Based on ALKBH5 Open
Background N6-methyladenosine(m6A) RNA regulators play important roles in cancers, but the functions and mechanism of them have not been demonstrated clearly in gastric cancer (GC). Methods In this study, the GC samples with clinical infor…
View article: The potential application of natural products in cutaneous wound healing: A review of preclinical evidence
The potential application of natural products in cutaneous wound healing: A review of preclinical evidence Open
Under normal circumstances, wound healing can be summarized as three processes. These include inflammation, proliferation, and remodeling. The vast majority of wounds heal rapidly; however, a large percentage of nonhealing wounds have stil…
View article: Retrospective Analysis of the Risk Factors and Drug Resistance of Pathogenic Bacteria in Systemic Inflammatory Response Syndrome After Ureteroscopic Holmium Laser Lithotripsy for Impacted Ureteral Calculi
Retrospective Analysis of the Risk Factors and Drug Resistance of Pathogenic Bacteria in Systemic Inflammatory Response Syndrome After Ureteroscopic Holmium Laser Lithotripsy for Impacted Ureteral Calculi Open
Quangang Yuan,1,* Jiang Guo,2,* Long He,1 Qiulin Chen,1 Xianhong Zou,1 Siming Yang,1 Zhenyang Zhang1 1Department of Urology, Chongqing Hechuan Hongren Hospital, Chongqing, 401520, People’s Republic of China; 2Department of Urology,…
View article: Epidemiology and clinical characteristics of burns in mainland China from 2009 to 2018
Epidemiology and clinical characteristics of burns in mainland China from 2009 to 2018 Open
Background Burn injuries place a heavy burden on the global healthcare system. However, there is still a lack of nationwide studies on the epidemiological characteristics of burn patients in mainland China. The present study aims to accura…
View article: Nerve transfer with 3D-printed branch nerve conduits
Nerve transfer with 3D-printed branch nerve conduits Open
Background Nerve transfer is an important clinical surgical procedure for nerve repair by the coaptation of a healthy donor nerve to an injured nerve. Usually, nerve transfer is performed in an end-to-end manner, which will lead to functio…
View article: Effects of Gelatin Methacrylate Hydrogel on Corneal Repair and Regeneration in Rats
Effects of Gelatin Methacrylate Hydrogel on Corneal Repair and Regeneration in Rats Open
Our research provides new ideas for the future development of LKP and tissue-engineered corneas.
View article: Burns Impair Blood-Brain Barrier and Mesenchymal Stem Cells Can Reverse the Process in Mice
Burns Impair Blood-Brain Barrier and Mesenchymal Stem Cells Can Reverse the Process in Mice Open
Neurological syndromes are observed in numerous patients who suffer burns, which add to the economic burden of societies and families. Recent studies have implied that blood-brain barrier (BBB) dysfunction is the key factor that induces th…
View article: Bacterial Cellulose: Functional Modification and Wound Healing Applications
Bacterial Cellulose: Functional Modification and Wound Healing Applications Open
Significance: Wound dressings are frequently used for wound covering and healing. Ideal wound dressings should provide a moist environment for wounds and actively promote wound healing and skin recovery. The materials used as ideal wound d…
View article: Stiffness-mediated mesenchymal stem cell fate decision in 3D-bioprinted hydrogels
Stiffness-mediated mesenchymal stem cell fate decision in 3D-bioprinted hydrogels Open
Background Hydrogels with tuneable mechanical properties are an attractive material platform for 3D bioprinting. Thus far, numerous studies have confirmed that the biophysical cues of hydrogels, such as stiffness, are known to have a profo…
View article: Correlation between the physical parameters and the electrochemical performance of a silicon anode in lithium-ion batteries
Correlation between the physical parameters and the electrochemical performance of a silicon anode in lithium-ion batteries Open
Lithium-ion battery anode used as silicon particles were obtained from different major suppliers, and they were characterized by different spectroscopic techniques and evaluated by electrochemical experiments. Correlations between the key …
View article: Dimethylacrylamide, a novel electrolyte additive, can improve the electrochemical performances of silicon anodes in lithium-ion batteries
Dimethylacrylamide, a novel electrolyte additive, can improve the electrochemical performances of silicon anodes in lithium-ion batteries Open
To enhance the electrochemical properties of silicon anodes in lithium-ion batteries, dimethylacrylamide (DMAA) was selected as a novel electrolyte additive.
View article: Anesthesia and Surgery Impair Blood–Brain Barrier and Cognitive Function in Mice
Anesthesia and Surgery Impair Blood–Brain Barrier and Cognitive Function in Mice Open
Blood-brain barrier (BBB) dysfunction, e.g., increase in BBB permeability, has been reported to contribute to cognitive impairment. However, the effects of anesthesia and surgery on BBB permeability, the underlying mechanisms, and associat…
View article: Supplementary Material for: Nrf2- and Bach1 May Play a Role in the Modulation of Ultraviolet A-Induced Oxidative Stress by Acetyl-11-Keto-β-Boswellic Acid in Skin Keratinocytes
Supplementary Material for: Nrf2- and Bach1 May Play a Role in the Modulation of Ultraviolet A-Induced Oxidative Stress by Acetyl-11-Keto-β-Boswellic Acid in Skin Keratinocytes Open
Background: Exposure of human skin to solar ultraviolet A (UVA) irradiation causes severe oxidative stress with damage to various cellular components and concomitant inflammation and carcinogenesis. Objective: The aim of this study is to i…