Simo Sun
YOU?
Author Swipe
A chromosome-level genome resource for the lethal tapeworm <i>Sparganum proliferum</i>, with candidate genomic safe harbours for functional genetics Open
Sparganum proliferum is an enigmatic and highly proliferative cestode known for its ability to form invasive larval infections in mammalian hosts. Here, we present the first chromosome-level genome assembly for a member of the order Diphyl…
Rapid chromosome evolution and acquisition of thermosensitive stochastic sex determination in nematode androdioecious hermaphrodites Open
The factors contributing to evolution of androdioecy, the coexistence of hermaphrodites and males such as in Caenorhabditis elegans , remains poorly known. However, nematodes exhibit androdioecy in at last 13 genera with the predatory genu…
Evolutionary changes of noncoding elements associated with transition of sexual mode in <i>Caenorhabditis</i> nematodes Open
The transition of the sexual mode occurs widely in animal evolution. In Caenorhabditis nematodes, androdioecy, a sexual polymorphism composed of males and hermaphrodites having the ability to self-fertilize, has evolved independently multi…
Experience-Dependent Behavioral Plasticity in Avoiding Epigallocatechin Gallate (EGCG) Requires DAF-16/FOXO in the AIY Interneurons of <i>Caenorhabditis elegans</i> Open
Bitterness and astringency are the aversive tastes in mammals. In humans, aversion to bitterness and astringency may be reduced depending on the eating experience. However, the cellular and molecular mechanisms underlying plasticity in pre…
Syntenic relationship of chromosomes in <i>Strongyloides</i> species and <i>Rhabditophanes diutinus</i> based on the chromosome-level genome assemblies Open
The Strongyloides clade, to which the parasitic nematode genus Strongyloides belongs, contains taxa with diverse lifestyles, ranging from free-living to obligate vertebrate parasites. Reproductive strategies are also diverse in this group …
Chromosome fusions repatterned recombination rate and facilitated reproductive isolation during Pristionchus nematode speciation Open
Large-scale genome-structural evolution is common in various organisms. Recent developments in speciation genomics revealed the importance of inversions, whereas the role of other genome-structural rearrangements, including chromosome fusi…
Supplementary Tables S1 to S3 from Syntenic relationship of chromosomes in <i>Strongyloides</i> species and <i>Rhabditophanes diutinus</i> based on the chromosome-level genome assemblies Open
Strongyloides clade, to which the parasitic nematode genus Strongyloides belongs, contains taxa with diverse lifestyles, ranging from free-living to obligate vertebrate parasites. Reproductive strategies are also diverse in this group of n…
Supplementary Tables S1 to S3 from Syntenic relationship of chromosomes in <i>Strongyloides</i> species and <i>Rhabditophanes diutinus</i> based on the chromosome-level genome assemblies Open
Strongyloides clade, to which the parasitic nematode genus Strongyloides belongs, contains taxa with diverse lifestyles, ranging from free-living to obligate vertebrate parasites. Reproductive strategies are also diverse in this group of n…
The GATA factor ELT-3 specifies endoderm in <i>Caenorhabditis angaria</i> in an ancestral gene network Open
Endoderm specification in Caenorhabditis elegans occurs through a network in which maternally provided SKN-1/Nrf, with additional input from POP-1/TCF, activates the GATA factor cascade MED-1,2→END-1,3→ELT-2,7. Orthologues of the MED, END …
The compact genome of a new Caenorhabditis species Caenorhabditis niphades n. sp., isolated from Niphades beetles Open
The first metazoan genome sequenced, that of Caenorhabditis elegans , impulse animal genome evolution studies. To date > 50 species from the genus Caenorhabditis have been sequenced, allowing research on genome variation. In the present st…
Possible stochastic sex determination in Bursaphelenchus nematodes Open
Sex determination mechanisms evolve surprisingly rapidly, yet little is known in the large nematode phylum other than for Caenorhabditis elegans , which relies on chromosomal XX-XO sex determination and a dosage compensation mechanism. Her…
Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation Open
The cryptic parasite Sparganum proliferum proliferates in humans and invades tissues and organs. Only scattered cases have been reported, but S. proliferum infection is always fatal. However, S. proliferum ’s phylogeny and life cycle remai…
Telomere-to-Telomere Genome Assembly of Bursaphelenchus okinawaensis Strain SH1 Open
Bursaphelenchus okinawaensis is a self-fertilizing, hermaphroditic, fungal-feeding nematode used as a laboratory model for the genus Bursaphelenchus , which includes the important pathogen Bursaphelenchus xylophilus . Here, we report the n…
Nearly Complete Genome Assembly of the Pinewood Nematode Bursaphelenchus xylophilus Strain Ka4C1 Open
Bursaphelenchus xylophilus has been destroying pine forests in East Asia and western Europe. Here, we report its nearly complete genomic sequence containing five ∼12-Mb scaffolds and one ∼15-Mb scaffold representing six chromosomes. Large …
Toll-like receptor homolog TOL-1 regulates <i>Bifidobacterium infantis</i>-elicited longevity and behavior in <i>Caenorhabditis elegans</i> Open
Bifidobacterium infantis, a Gram-positive bacterium, is one of the commonly used probiotics. We previously showed that B. infantis modified host defense systems and extended the lifespan of the nematode Caenorhabditis elegans. In the prese…
Clostridium butyricum MIYAIRI 588 Increases the Lifespan and Multiple-Stress Resistance of Caenorhabditis elegans Open
Clostridium butyricum MIYAIRI 588 (CBM 588), one of the probiotic bacterial strains used for humans and domestic animals, has been reported to exert a variety of beneficial health effects. The effect of this probiotic on lifespan, however,…
The small GTPase ARF-1.2 is a regulator of unicellular tube formation in Caenorhabditis elegans Open
The membrane trafficking events that regulate unicellular tube formation and maintenance are not well understood. Here, using an RNAi screen, we identified the small GTPase ARF1 homolog ARF-1.2 as a regulator of excretory tube formation in…
<i>Caenorhabditis elegans</i> homologue of Prox1/Prospero is expressed in the glia and is required for sensory behavior and cold tolerance Open
The Caenorhabditis elegans ( C. elegans ) amphid sensory organ contains only 4 glia‐like cells and 24 sensory neurons, providing a simple model for analyzing glia or neuron‐glia interactions. To better characterize glial development and fu…