Explanipedia

Low-field MRI as a multiparametric tool for large engineered tissue characterization Open

Christophe A. Marquette, Yilbert Gimènez, Valernst Gilmus, Elliott Cowles, Lucie Essayan , et al. · 2025

Advances in 3D bioprinting have enabled the fabrication of large and complex engineered tissues, but their increasing size demands non-invasive tools for monitoring structure, maturation, and perfusion. Magnetic Resonance Imaging (MRI) off…

Exploring multiple monitoring modalities for large-scale 3D tissue cultivation in bioreactor Open

Laura Chastagnier, Sarah Pragnère, Yilbert Gimènez, Céline Loubière, Lucie Essayan , et al. · 2025

As the field of tissue engineering advances toward clinically viable, large-scale biofabrication, there is an urgent need for non-invasive, real-time monitoring tools capable of assessing the dynamic maturation of 3D bioprinted tissues. Th…

Exploring multiple bioprocess monitoring modalities for Large-scale 3D Bioprinted Tissue Cultivation Open

Laura Chastagnier, Sarah Pragnère, Yilbert Gimènez, Céline Loubière, Naima el-Kholti , et al. · 2024

In tissue engineering (TE) and regenerative medicine (RM), challenges persist in achieving optimal tissue maturation due to uncontrolled physicochemical environments and the necessity for a dynamic nutrient supply. Real-time monitoring too…

Eco-conception de dispositifs plastroniques 3D : Electronique Structurelle Surmoulée sur Acide PolyLActique Open

Caroline Goument, Valernst Gilmus, Philippe Lombard, Tony Gerges, Simon A. Lambert , et al. · 2023

International audience

In-Mold Electronics with Biosourced and Biodegradable Polymers Open

Caroline Goument, Tony Gerges, Philippe Lombard, Hayet Lakhdar, Murat Arli , et al. · 2023

International audience

In-Mold Electronics on Poly(Lactic Acid): towards a more sustainable mass production of plastronic devices Open

Caroline Goument, Tony Gerges, Philippe Lombard, Hayet Lakhdar, Murat Arli , et al. · 2023

Électronique Structurelle Surmoulée sur acide PolyLActique (PLA) Open

Caroline Goument, Tony Gerges, Philippe Lombard, Valernst Gilmus, Hayet Lakhdar , et al. · 2022

Numerical simulation of wave propagation through interfaces using the extended finite element method for magnetic resonance elastography Open

Quanshangze Du, Aline Bel‐Brunon, Simon A. Lambert, Nahiène Hamila · 2022

Magnetic resonance elastography (MRE) is an elasticity imaging technique for quantitatively assessing the stiffness of human tissues. In MRE, finite element method (FEM) is widely used for modeling wave propagation and stiffness reconstruc…

Actuators for MRE: New Perspectives With Flexible Electroactive Materials Open

Jean-Lynce Gnanago, Jean‐Fabien Capsal, Tony Gerges, Philippe Lombard, V. Semet , et al. · 2021

Since 1995, Magnetic Resonance Elastography (MRE) has been constantly developed as a non-invasive diagnostic tool for quantitative mapping of mechanical properties of biological tissues. Indeed, mechanical properties of tissues vary over f…

Introduction Open

Fransiska Louwagie, Simon A. Lambert · 2021

This thematic issue arises from the symposium ‘Tradition and Innovation in Franco-Belgian Bande dessinée’, held at the University of Leicester on 13 March 2020. Over three panels with a respective focus on ‘Revisiting the Classics’, ‘Conte…

An automated system for fast transfer and injection of hyperpolarized solutions Open

Morgan Ceillier, Olivier Cala, Théo El Daraï, Samuel F. Cousin, Quentin Stern , et al. · 2021

Compact MRI bioreactor for real-time monitoring 3D printed tissue-engineered constructs. Open

Jean-Lynce Gnanago, Tony Gerges, Laura Chastagnier, Emma Petiot, V. Semet , et al. · 2021

International audience

Human colon imaging: simulation of novel SwiM RE-coils Open

Hamza Raki, Kevin Tse Ve Koon, Henri Souchay, Simon A. Lambert, Fraser Robb , et al. · 2020

International audience

Endoluminal imaging with MEMS in series with loop coil for active decoupling Open

Hamza Raki, Kevin Tse Ve Koon, Isabelle Saniour, Henri Souchay, Simon A. Lambert , et al. · 2020

International audience

3D Plastronics for Smartly Integrated Magnetic Resonance Imaging Coils Open

Tony Gerges, V. Semet, Philippe Lombard, Sophie Gaillard, Michel Cabrera , et al. · 2020

Over the last four decades, magnetic resonance imaging has become the gold standard imaging technique in many medical diagnoses for brain, cardiac, and liver disease. However, due to low critical mass and great scientific challenges, instr…

Serial and Parallel Active Decoupling Characterization Using RF MEMS Switches for Receiver Endoluminal Coils at 1.5 T Open

Hamza Raki, Kevin Tse Ve Koon, Isabelle Saniour, Henri Souchay, Simon A. Lambert , et al. · 2020

International audience

The apparent mechanical effect of isolated amyloid‐β and α‐synuclein aggregates revealed by multi‐frequency MRE Open

Mathilde Bigot, Fabien Chauveau, Camille Amaz, Ralph Sinkus, Olivier Beuf , et al. · 2019

Several biological processes are involved in dementia, and fibrillar aggregation of misshaped endogenous proteins appears to be an early hallmark of neurodegenerative disease. A recently developed means of studying neurodegenerative diseas…

Design of a reconfigurable endoluminal coil using MEMS switches Open

Hamza Raki, Kévin Tse-Ve-Koon, Henri Souchay, Fraser Robb, Simon A. Lambert , et al. · 2019

International audience

Characterization of fibril aggregates in ex vivo rat brain with multi- frequency MR Elastography -Preliminary results Open

Mathilde Bigot, Fabien Chauveau, Ralph Sinkus, Olivier Beuf, Simon A. Lambert · 2019

International audience

Plastronique 3D et 3D-MID, programme innovant d'enseignement supérieur et de formation à l'Université de Lyon Open

Ph. Lombard, Thiago Gomes Zaki Gerges, B. Allard, Simon A. Lambert, M. Cabrera · 2019

En 2015, une enquête menée par la Fondation pour l'Université de Lyon (1), auprès d’une centaine d’entreprises françaises, a montré que l'un des freins majeurs au développement de l’électronique sur substrat polymère, plus communément appe…

Magnetic Resonance Elastography of Rodent Brain Open

Mathilde Bigot, Fabien Chauveau, Olivier Beuf, Simon A. Lambert · 2018

Magnetic resonance elastography (MRE) is a non-invasive imaging technique, using the propagation of mechanical waves as a probe to palpate biological tissues. It consists in three main steps: production of shear waves within the tissue; en…

Rheological determinants for simultaneous staging of hepatic fibrosis and inflammation in patients with chronic liver disease Open

Ralph Sinkus, Simon A. Lambert, Khaled Z. Abd‐Elmoniem, Caryn G. Morse, Theo Heller , et al. · 2018

The purpose of this study is to investigate the use of fundamental rheological parameters as quantified by MR elastography (MRE) to measure liver fibrosis and inflammation simultaneously in humans. MRE was performed on 45 patients at 3 T u…

Development of an elastography bench for MR exam of small samples Open

Mathilde Bigot, Hugo Dorez, Céline A. Mandon, Christophe A. Marquette, Kévin Tse-Ve-Koon , et al. · 2017

Development of an elastography bench for histology and engineered tissue study-Preliminary results Open

Mathilde Bigot, Hugo Dorez, Céline A. Mandon, Christophe A. Marquette, Kevin Tse Ve Koon , et al. · 2017

International audience

Active control of the spatial MRI phase distribution with optimal control theory Open

Pauline Lefebvre, Éric Van Reeth, H. Ratiney, Olivier Beuf, Élisabeth Brusseau , et al. · 2017

Effect of cerebral protein aggregates on tissue mechanical properties measured by Magnetic Resonance Elastography Open

Mathilde Bigot, Fabien Chauveau, Céline A. Mandon, Olivier Beuf, Simon A. Lambert · 2016

Strong antineoplastic effects of metformin in preclinical models of liver carcinogenesis Open

François Cauchy, Mouniya Mebarki, Benjamin Leporq, Samira Laouirem, Miguel Albuquerque , et al. · 2016

Studies suggest that metformin, widely used for treating Type 2 diabetes, possesses innate antineoplastic properties. For metabolic syndrome patients with hepatocellular carcinoma (HCC), metformin may provide antitumoral effects. We evalua…

Comparison of viscoelastic property characterization of plastisol phantoms with magnetic resonance elastography and high-frequency rheometry Open

Pauline Lefebvre, Kevin Tse Ve Koon, Élisabeth Brusseau, Stéphane Nicolle, J.-F. Palieme , et al. · 2016

This study aims at evaluating Magnetic Resonance Elastography (MRE) as a reliable technique for the characterization of viscoelastic properties of soft tissues. Three phantoms with different concentrations of plastisol and softener were pr…

Eau décalée : un biomarqueur IRM de l’obésité ? Open

Angéline Nemeth, H. Ratiney, Benjamin Leporq, Simon A. Lambert, Bérénice Ségrestin , et al. · 2016

L’eau (H2O) est le principal constituant du corps humain. La quantite moyenne d’eau contenue dans un organisme adulte est de 65 %, ce qui correspond a environ 45 litres d’eau pour une personne de 70 kilogrammes. L’imagerie par resonance ma…

Microvasculature alters the dispersion properties of shear waves – a multi‐frequency MR elastography study Open

Lauriane Jugé, Anne Petiet, Simon A. Lambert, Pascal Nicole, Simon Chatelin , et al. · 2015

Magnetic Resonance Elastography (MRE) uses macroscopic shear wave propagation to quantify mechanical properties of soft tissues. Micro‐obstacles are capable of affecting the macroscopic dispersion properties of shear waves. Since disease o…

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