Simon Biddle
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View article: Identification of equine in vitro metabolites of seven non‐steroidal selective androgen receptor modulators for doping control purposes
Identification of equine in vitro metabolites of seven non‐steroidal selective androgen receptor modulators for doping control purposes Open
Selective androgen receptor modulators, SARMs, are a large class of compounds developed to provide therapeutic anabolic effects with minimal androgenic side effects. A wide range of these compounds are available to purchase online and thus…
View article: Equine metabolism of the selective androgen receptor modulator AC‐262536 <i>in vitro</i> and in urine, plasma and hair following oral administration
Equine metabolism of the selective androgen receptor modulator AC‐262536 <i>in vitro</i> and in urine, plasma and hair following oral administration Open
AC‐262536 is one of a number of selective androgen receptor modulators that are being developed by the pharmaceutical industry for treatment of a range of clinical conditions including androgen replacement therapy. Though not available the…
View article: Bioformation of boldenone and related precursors/metabolites in equine feces and urine, with relevance to doping control
Bioformation of boldenone and related precursors/metabolites in equine feces and urine, with relevance to doping control Open
Boldenone (1‐dehydrotestosterone) is an exogenous anabolic‐androgenic steroid (AAS) but is also known to be endogenous in the entire male horse and potentially formed by microbes in voided urine, the gastrointestinal tract, or feed resulti…
View article: Re‐evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses
Re‐evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses Open
Xylazine is widely used worldwide as a short‐acting sedative in general equine and racing practice. In the UK, although it has a legitimate use during training, equine anti‐doping rules state it is a prohibited substance on race day. The a…