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View article: Standard care vs. TRIVEntricular pacing in Heart Failure (STRIVE HF): a prospective multicentre randomized controlled trial of triventricular pacing vs. conventional biventricular pacing in patients with heart failure and intermediate QRS left bundle branch block
Standard care vs. TRIVEntricular pacing in Heart Failure (STRIVE HF): a prospective multicentre randomized controlled trial of triventricular pacing vs. conventional biventricular pacing in patients with heart failure and intermediate QRS left bundle branch block Open
Aims To determine whether triventricular (TriV) pacing is feasible and improves CRT response compared to conventional biventricular (BiV) pacing in patients with left bundle branch block (LBBB) and intermediate QRS prolongation (120–150 ms…
View article: Coronary arteriovenous fistula with associated aneurysm
Coronary arteriovenous fistula with associated aneurysm Open
A 56-year-old man was seen in cardiology clinic with exertional chest pain, most marked when walking uphill. He was a heavy smoker but had no other cardiovascular risk factors. His 12-lead ECG was normal, and a CT coronary angiogram (CTCA)…
View article: Pacemaker‐induced ventricular fibrillation during radiofrequency catheter ablation for ventricular tachycardia
Pacemaker‐induced ventricular fibrillation during radiofrequency catheter ablation for ventricular tachycardia Open
Prior to ventricular tachycardia ablation, this patient's cardiac implantable electronic device (CIED) was temporarily programmed to backup pacing mode with tachycardia therapies disabled. During radiofrequency energy delivery, the patient…
View article: Evaluation of [13N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain.
Evaluation of [13N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain. Open
Purpose: The conversion of synaptic glutamate to glutamine in astrocytes by glutamine synthetase (GS) is critical to maintaining healthy brain activity and may be disrupted in several brain disorders. As the GS catalysed conversion of glut…
View article: 58 First-phase ejection fraction predicts repsonse to cardiac resynchronization therapy and adverse outcomes
58 First-phase ejection fraction predicts repsonse to cardiac resynchronization therapy and adverse outcomes Open
Background Cardiac Resynchronization Therapy (CRT) is an important therapeutic treatment for chronic heart failure. However, even in carefully selected cases up to 40% of patient fail to respond. First-phase ejection fraction (EF1), the ej…
View article: High mean entropy calculated from cardiac MRI texture analysis is associated with antitachycardia pacing failure
High mean entropy calculated from cardiac MRI texture analysis is associated with antitachycardia pacing failure Open
Background Antitachycardia pacing (ATP), which may avoid unnecessary implantable cardioverter‐defibrillator (ICD) shocks, does not always terminate ventricular arrhythmias (VAs). Mean entropy calculated using cardiac magnetic resonance tex…
View article: Evaluation of [13N]ammonia Positron Emission Tomography for Quantifying Glutamine Synthetase Activity in the Human Brain.
Evaluation of [13N]ammonia Positron Emission Tomography for Quantifying Glutamine Synthetase Activity in the Human Brain. Open
Purpose The conversion of synaptic glutamate to glutamine in astrocytes by glutamine synthetase (GS) is critical to maintaining healthy brain activity and may be disrupted in several brain disorders. As the GS catalysed conversion of gluta…
View article: Transvenous lead extraction procedures in women based on ESC-EHRA EORP European Lead Extraction ConTRolled ELECTRa registry: is female sex a predictor of complications?
Transvenous lead extraction procedures in women based on ESC-EHRA EORP European Lead Extraction ConTRolled ELECTRa registry: is female sex a predictor of complications? Open
Aims Female sex is considered an independent risk factor of transvenous leads extraction (TLE) procedure. The aim of the study was to evaluate the effectiveness of TLE in women compared with men. Methods and results A post hoc analysis of …
View article: Erratum to “Comparison of Echocardiographic and Electrocardiographic Mapping for Cardiac Resynchronisation Therapy Optimisation”
Erratum to “Comparison of Echocardiographic and Electrocardiographic Mapping for Cardiac Resynchronisation Therapy Optimisation” Open
[This corrects the article DOI: 10.1155/2019/4351693.].
View article: Emerging role of cardiac computed tomography in heart failure
Emerging role of cardiac computed tomography in heart failure Open
Despite medical advancements, the prognosis of patients with heart failure remains poor. While echocardiography and cardiac magnetic resonance imaging remain at the forefront of diagnosing and monitoring patients with heart failure, cardia…
View article: Differential effect with septal and apical RV pacing on ventricular activation in patients with left bundle branch block assessed by non-invasive electrical imaging and in silico modelling
Differential effect with septal and apical RV pacing on ventricular activation in patients with left bundle branch block assessed by non-invasive electrical imaging and in silico modelling Open
(ClinicalTrials.gov identifier: NCT01831518).
View article: Comparison of Echocardiographic and Electrocardiographic Mapping for Cardiac Resynchronisation Therapy Optimisation
Comparison of Echocardiographic and Electrocardiographic Mapping for Cardiac Resynchronisation Therapy Optimisation Open
Study hypothesis . We sought to investigate the association between echocardiographic optimisation and ventricular activation time in cardiac resynchronisation therapy (CRT) patients, obtained through the use of electrocardiographic mappin…
View article: Optimization of <scp>CRT</scp> programming using non‐invasive electrocardiographic imaging to assess the acute electrical effects of multipoint pacing
Optimization of <span>CRT</span> programming using non‐invasive electrocardiographic imaging to assess the acute electrical effects of multipoint pacing Open
Aim Quadripolar lead technology and multi‐point pacing ( MPP ) are important clinical adjuncts in cardiac resynchronization therapy ( CRT ) pacing aimed at reducing the rate of non‐response to therapy. Mixed results have been achieved usin…
View article: Variation in activation time during bipolar vs extended bipolar left ventricular pacing
Variation in activation time during bipolar vs extended bipolar left ventricular pacing Open
Background Cardiac resynchronization therapy (CRT) is typically delivered via quadripolar leads that allow stimulation using either true bipolar pacing, where stimulation occurs between two electrodes (BP) on the quadripolar lead, or exten…
View article: Optimal site selection and image fusion guidance technology to facilitate cardiac resynchronization therapy
Optimal site selection and image fusion guidance technology to facilitate cardiac resynchronization therapy Open
Targeted LV lead deployment is associated with reductions in morbidity and mortality. Assessment of tissue characterization and electrical latency are critical and can be achieved in a number of ways. Ultimately, the constraints of coronar…
View article: Guidance for Optimal Site Selection of a Leadless Left Ventricular Endocardial Electrode Improves Acute Hemodynamic Response and Chronic Remodeling
Guidance for Optimal Site Selection of a Leadless Left Ventricular Endocardial Electrode Improves Acute Hemodynamic Response and Chronic Remodeling Open
Guided endocardial implants were associated with a higher degree of chronic LV remodeling compared with historical nonguided approaches.
View article: Electrical latency predicts the optimal left ventricular endocardial pacing site: results from a multicentre international registry
Electrical latency predicts the optimal left ventricular endocardial pacing site: results from a multicentre international registry Open
Identifying viable LVENDO tissue which displays late electrical activation is crucial to identifying the optimal BiVENDO pacing site. Stimulating late activating tissue (LVLED >50%) yields greater improvements in AHR however, the optimal l…
View article: Beat-to-Beat Variability of Ventricular Action Potential Duration Oscillates at Low Frequency During Sympathetic Provocation in Humans
Beat-to-Beat Variability of Ventricular Action Potential Duration Oscillates at Low Frequency During Sympathetic Provocation in Humans Open
Background: The temporal pattern of ventricular repolarization is of critical importance in arrhythmogenesis. Enhanced beat-to-beat variability (BBV) of ventricular action potential duration (APD) is pro-arrhythmic and is increased during …
View article: Changes in contractility determine coronary haemodynamics in dyssynchronous left ventricular heart failure, not vice versa
Changes in contractility determine coronary haemodynamics in dyssynchronous left ventricular heart failure, not vice versa Open
Acutely increasing coronary flow with adenosine in patients with systolic heart failure does not increase contractility. Changes in coronary flow with biventricular pacing are likely to be a consequence of enhanced cardiac contractility fr…
View article: 994Quantitative assessment of myocardial scar heterogeneity using texture analysis to predict implantable cardioverter defibrillator therapies using cardiac magnetic resonance imaging
994Quantitative assessment of myocardial scar heterogeneity using texture analysis to predict implantable cardioverter defibrillator therapies using cardiac magnetic resonance imaging Open
Background: Ventricular tachycardias (VTs) in non-ischemic cardiomyopathy (NICM) are related to the amount and architecture of fibrosis with highest propensity for intermediate amounts and patchy architecture.Transmural activation delay (T…