Steffen Desch
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View article: Ultrasound versus angiographic guided access in transfemoral TAVI: intra-operator evaluation of vascular and bleeding complications
Ultrasound versus angiographic guided access in transfemoral TAVI: intra-operator evaluation of vascular and bleeding complications Open
Background Both angiography roadmap (RM) and ultrasound (US) are commonly used to obtain femoral arterial access during transfemoral transcatheter aortic valve implantation (TAVI). In this analysis, we sought to evaluate the effect of impl…
View article: Dynamic biomarker trajectories in the first 72 h after infarct-related cardiac arrest: a novel approach to early risk stratification
Dynamic biomarker trajectories in the first 72 h after infarct-related cardiac arrest: a novel approach to early risk stratification Open
In patients who survive the initial critical phase after cardiac arrest, early prognostication remains limited due to evolving clinical trajectories. Admission biomarkers alone are insufficient for making definitive decisions. The post-res…
View article: Prognostic impact of SCAI shock severity classes in AMI‐related cardiogenic shock: A sub‐study of the ECLS‐SHOCK Trial
Prognostic impact of SCAI shock severity classes in AMI‐related cardiogenic shock: A sub‐study of the ECLS‐SHOCK Trial Open
Aims The Society for Cardiovascular Angiography and Interventions (SCAI) Classification provides risk stratification of patients with acute myocardial infarction complicated by cardiogenic shock (AMI‐CS). This sub‐study of the ECLS‐SHOCK t…
View article: Inferior Vena Cava Ultrasound to Guide Decongestion in Acute Decompensated Heart Failure
Inferior Vena Cava Ultrasound to Guide Decongestion in Acute Decompensated Heart Failure Open
Additional ultrasound evaluation of IVC diameters did not improve decongestion treatment compared with clinical assessment alone among patients admitted for ADHF. (Ultrasound Evaluation of the IVC in Addition to Clinical Assessment to Guid…
View article: Osteoporosis screening and major osteoporotic fracture prediction by cranial computed tomography-derived Hounsfield units: a multi-center study on opportunistic osteoporosis screening
Osteoporosis screening and major osteoporotic fracture prediction by cranial computed tomography-derived Hounsfield units: a multi-center study on opportunistic osteoporosis screening Open
Cranial computed tomography-derived Hounsfield units may assist to detect patients with densitometric osteoporosis and with major osteoporotic fractures at earlier stages, thereby facilitating early treatment and future fracture prevention.
View article: Peri-Interventional Anesthesia Strategies for Transcatheter Aortic Valve Implantation: A Multicenter, Randomized, Controlled, Noninferiority Trial
Peri-Interventional Anesthesia Strategies for Transcatheter Aortic Valve Implantation: A Multicenter, Randomized, Controlled, Noninferiority Trial Open
BACKGROUND: Minimalist treatment strategies for transcatheter aortic valve implantation have been widely adopted because of continued procedural evolution, but large randomized trials are lacking. The DOUBLE-CHOICE trial (Randomized Study …
View article: Outcomes Beyond 10 Years After Transcatheter Aortic Valve Implantation in High‐Risk Patients With Severe Aortic Valve Stenosis
Outcomes Beyond 10 Years After Transcatheter Aortic Valve Implantation in High‐Risk Patients With Severe Aortic Valve Stenosis Open
Background Limited data is available on long‐term outcomes and valve durability measures of transcatheter aortic valve implantation (TAVI). Aims This study sought to assess clinical and echocardiographic outcomes of high‐risk patients duri…
View article: A nationwide analysis of resource utilization and safety in patients undergoing mitral transcatheter edge-to-edge repair
A nationwide analysis of resource utilization and safety in patients undergoing mitral transcatheter edge-to-edge repair Open
Mitral TEER has become safer and more efficient due to technological advances, operator experience and centralized care. Caution is advised in highly comorbid patients.
View article: Out-of-hospital cardiac arrest - insights from the german cardiac arrest registry (G-CAR)
Out-of-hospital cardiac arrest - insights from the german cardiac arrest registry (G-CAR) Open
Background In Europe, more than 300,000 people per year suffer from out-of-hospital cardiac arrest (OHCA). Despite advances in emergency and intensive care medicine, survival rates with good neurological outcome remain low. Due to the acui…
View article: Risk stratification of patients after successfully resuscitated cardiac arrest - The TOMAHAWK risk score.
Risk stratification of patients after successfully resuscitated cardiac arrest - The TOMAHAWK risk score. Open
Background Out-of-hospital cardiac arrest (OHCA) continues to be associated with high mortality rates. Timely risk assessment is essential to inform appropriate therapeutic strategies. However, existing OHCA risk scores are often based on …
View article: ECMO-related complications and mortality in patients with infarct-related cardiogenic shock
ECMO-related complications and mortality in patients with infarct-related cardiogenic shock Open
Background Recent randomised controlled trials, along with a meta-analysis of individual patient data, have demonstrated that the routine application of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) does not confer a survival…
View article: Different Mechanical Circulatory Support Strategies for Infarct-Related Cardiogenic Shock
Different Mechanical Circulatory Support Strategies for Infarct-Related Cardiogenic Shock Open
Bailout and escalated MCS therapy is associated with numerically higher 30-day mortality compared with upfront ECLS use only. Bailout MCS use is also associated with higher need for renal replacement therapy. (Extracorporeal Life Support i…
View article: Prognostic Impact of Admission Time in Infarct-Related Cardiogenic Shock
Prognostic Impact of Admission Time in Infarct-Related Cardiogenic Shock Open
The prognosis in AMI-CS was not affected by admission time with a similar effect of ECLS during on- and off-hours.
View article: Identifying prognostic factors in patients with cardiogenic shock undergoing VA-ECMO treatment: insights from ECLS-SHOCK using machine learning
Identifying prognostic factors in patients with cardiogenic shock undergoing VA-ECMO treatment: insights from ECLS-SHOCK using machine learning Open
Background/Introduction Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has not been shown to reduce short-term mortality in patients with acute myocardial infarction complicated by cardiogenic shock. However, whether some patie…
View article: Early risk stratification of patients with acute myocardial infarction complicated by severe cardiogenic shock - The ECLS-SHOCK Risk Score
Early risk stratification of patients with acute myocardial infarction complicated by severe cardiogenic shock - The ECLS-SHOCK Risk Score Open
Background Prognosis after acute myocardial infarction complicated by cardiogenic shock (AMI-CS) remains dismal. Timely risk stratification is crucial to make adequate treatment decisions. Existing CS scores are limited to either registry …
View article: Do DAN-GER-SHOCK eligible patients benefit from VA-ECMO treatment in infarct-related cardiogenic shock ? Results of an individual patient data meta-analysis.
Do DAN-GER-SHOCK eligible patients benefit from VA-ECMO treatment in infarct-related cardiogenic shock ? Results of an individual patient data meta-analysis. Open
Background In a recent meta-analysis of randomized controlled trials routine use of venous-arterial ECMO (VA-ECMO) did not improve outcome in patients with infarct related cardiogenic shock (CS). Since the rate of patients with cardiac arr…
View article: Interrater Variability of ML-Based CT-FFR in Patients without Obstructive CAD before TAVR: Influence of Image Quality, Coronary Artery Calcifications, and Location of Measurement
Interrater Variability of ML-Based CT-FFR in Patients without Obstructive CAD before TAVR: Influence of Image Quality, Coronary Artery Calcifications, and Location of Measurement Open
Objectives: CT-derived fractional flow reserve (CT-FFR) can improve the specificity of coronary CT-angiography (cCTA) for ruling out relevant coronary artery disease (CAD) prior to transcatheter aortic valve replacement (TAVR). However, li…
View article: Revascularization Strategy in Myocardial Infarction with Multivessel Disease
Revascularization Strategy in Myocardial Infarction with Multivessel Disease Open
The proportion of patients with multivessel coronary artery disease in individuals experiencing acute coronary syndrome (ACS) varies based on age and ACS subtype. In patients with ST-segment elevation myocardial infarction (STEMI) without …
View article: A study of bailout plug-based closure after failed suture-based closure in patients undergoing transfemoral TAVI
A study of bailout plug-based closure after failed suture-based closure in patients undergoing transfemoral TAVI Open
Bailout MANTA after ProGlide failure was effective and safe, but operator experience seems to be crucial. Further technological refinements to facilitate accurate placement appear necessary.
View article: Reperfusion Injury: How Can We Reduce It by Pre-, Per-, and Postconditioning
Reperfusion Injury: How Can We Reduce It by Pre-, Per-, and Postconditioning Open
While early coronary reperfusion via primary percutaneous coronary intervention (pPCI) is established as the most efficacious therapy for minimizing infarct size (IS) in acute ST-elevation myocardial infarction (STEMI), the restoration of …
View article: Interrater variability of ML-based CT-FFR during TAVR-planning: influence of image quality and coronary artery calcifications
Interrater variability of ML-based CT-FFR during TAVR-planning: influence of image quality and coronary artery calcifications Open
Objective To compare machine learning (ML)-based CT-derived fractional flow reserve (CT-FFR) in patients before transcatheter aortic valve replacement (TAVR) by observers with differing training and to assess influencing factors. Backgroun…
View article: Impact of Anaemia and Iron Deficiency on Outcomes in Cardiogenic Shock Complicating Acute Myocardial Infarction
Impact of Anaemia and Iron Deficiency on Outcomes in Cardiogenic Shock Complicating Acute Myocardial Infarction Open
Aims Anaemia and iron deficiency (ID) are common comorbidities in cardiovascular patients and are associated with a poor clinical status, as well as a worse outcome in patients with heart failure and acute myocardial infarction (AMI). Neve…
View article: The demise of extracorporeal membrane oxygenation in infarct‐related cardiogenic shock
The demise of extracorporeal membrane oxygenation in infarct‐related cardiogenic shock Open
Cardiogenic shock in acute myocardial infarction carries a dismal prognosis. In-hospital or 30-day mortality reaches 40% to 50%.1 Timely treatment of the coronary culprit lesion (usually by means of percutaneous coronary intervention) is t…