Simon Fürbacher
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View article: Development of a novel tobramycin dependent riboswitch
Development of a novel tobramycin dependent riboswitch Open
We herein report the selection and characterization of a new riboswitch dependent on the aminoglycoside tobramycin. Its dynamic range rivals even the tetracycline dependent riboswitch to be the current best performing, synthetic riboswitch…
View article: Single-step discovery of high-affinity RNA ligands by UltraSelex
Single-step discovery of high-affinity RNA ligands by UltraSelex Open
Aptamers, nucleic acid ligands against specific targets, have emerged as drug candidates, sensors, imaging tools, and nanotechnology building blocks. The most successful method for their development has been SELEX (Systematic Evolution of …