Simon Kayembe
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View article: Bold strides towards the elimination of gambiense human African trypanosomiasis (gHAT) as a public health problem—A case study of Angola
Bold strides towards the elimination of gambiense human African trypanosomiasis (gHAT) as a public health problem—A case study of Angola Open
Background The chronic form of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense and commonly referred to as gambiense -HAT (gHAT) is endemic in 7 of Angola’s 18 provinces. Major epidemics of the disease occurred i…
View article: Developing Strategies for Onchocerciasis Elimination Mapping and Surveillance Through The Diagnostic Network Optimization Approach
Developing Strategies for Onchocerciasis Elimination Mapping and Surveillance Through The Diagnostic Network Optimization Approach Open
Background Onchocerciasis (river blindness) is a filarial disease targeted for elimination of transmission. However, challenges exist to the implementation of effective diagnostic and surveillance strategies at various stages of eliminatio…
View article: Development and implementation of a strategy for intensified screening for gambiense human African trypanosomiasis in Kongo Central province, DRC
Development and implementation of a strategy for intensified screening for gambiense human African trypanosomiasis in Kongo Central province, DRC Open
This programme has demonstrated that it is possible to deploy passive screening for HAT at sub-country or country levels in the DRC, and this is made more effective when supplemented with reactive screening. Results and achievements showed…
View article: Performance evaluation of a prototype rapid diagnostic test for combined detection of gambiense human African trypanosomiasis and malaria
Performance evaluation of a prototype rapid diagnostic test for combined detection of gambiense human African trypanosomiasis and malaria Open
The HAT/Malaria Combined prototype RDT was as accurate as the individual malaria or gHAT RDTs. The HAT/Malaria Combined prototype RDT is therefore suitable for both malaria diagnosis and gHAT screening. However, there is a need to assess i…
View article: Prospective evaluation of a rapid diagnostic test for Trypanosoma brucei gambiense infection developed using recombinant antigens
Prospective evaluation of a rapid diagnostic test for Trypanosoma brucei gambiense infection developed using recombinant antigens Open
The recombinant antigen-based RDT was more sensitive than, and as specific as, the SD BIOLINE HAT. It was as sensitive as, but slightly less specific than CATT. While the practicality and cost-effectiveness of algorithms including several …