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Alejandro Aballay, Jen Arthur, Daniel Austin, Burkhard Backes, Partha Sarathi Banerjee , et al. · 2015

The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments Open

Parimala R. Vajjhala, Alvin Lu, Darren L. Brown, Siew Wai Pang, Vitaliya Sagulenko , et al. · 2015

Inflammasomes mediate inflammatory and cell death responses to pathogens and cellular stress signals via activation of procaspases-1 and -8. During inflammasome assembly, activated receptors of the NLR or PYHIN family recruit the adaptor p…