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View article: Evaluation of the safety of short-term follow-up CT for the management of consolidation in lung cancer screening
Evaluation of the safety of short-term follow-up CT for the management of consolidation in lung cancer screening Open
Objectives Focal consolidation on CT may be inflammatory or malignant, and PET-CT imaging is rarely discriminatory. Furthermore, consolidation may demonstrate spontaneous resolution obviating the need for PET-CT imaging. This retrospective…
View article: Non-invasive imaging in acute and chronic pulmonary embolism
Non-invasive imaging in acute and chronic pulmonary embolism Open
Acute pulmonary emboli can manifest as a spectrum of physiological status ranging from an incidental finding to life threatening right heart failure. We discuss the crucial role imaging plays in the accurate and rapid diagnosis. In additio…
View article: Silence of the lungs: comparing measures of slow and noncommunicating lung units from pulmonary function tests with computed tomography
Silence of the lungs: comparing measures of slow and noncommunicating lung units from pulmonary function tests with computed tomography Open
We consider the term “trapped air” either in the use of imaging or pulmonary function testing, something of a misnomer that can lead to an inaccurate assessment of an important physiological feature. Instead, we propose the term underventi…
View article: Left Atrial Appendage Pseudothrombus Is Associated With Stroke History in Patients With Atrial Fibrillation Undergoing Cardiac Computed Tomography
Left Atrial Appendage Pseudothrombus Is Associated With Stroke History in Patients With Atrial Fibrillation Undergoing Cardiac Computed Tomography Open
Background In nonvalvular atrial fibrillation (NVAF), the left atrial appendage (LAA) is the source of thrombus in up to 90% of patients. LAA pseudothrombus (LAAPT), defined as a filling defect on the initial but not the 60‐second delayed …
View article: The impact of hiatus hernia in hypersensitivity pneumonitis
The impact of hiatus hernia in hypersensitivity pneumonitis Open
Around 40% of patients with idiopathic pulmonary fibrosis (IPF) have a hiatus hernia (HH), the presence of which has been linked with greater lung function decline and increased mortality.1-3 HH has been reported in approximately one-third…
View article: P74 Evaluation of short-term follow-up CT for the management of consolidation in lung cancer screening
P74 Evaluation of short-term follow-up CT for the management of consolidation in lung cancer screening Open
Background There are no specific guidelines for the management of consolidation in lung cancer screening. BTS guidelines recommend PET-CT for solid nodules ≥300mm3, with a Brock score >10%. At times, consolidation has a nodular or mass-lik…
View article: P71 The utility of the herder score for guiding diagnostic investigations of nodules in lung cancer screening
P71 The utility of the herder score for guiding diagnostic investigations of nodules in lung cancer screening Open
Introduction Suspicious lung nodules on CT are typically investigated with a 18F-FDG PET-CT scan and a Herder score is calculated to guide management. BTS guidelines recommend that nodules with a score under 10% should be offered surveilla…
View article: Pulmonary hypertension: the hallmark of acute COVID-19 microvascular angiopathy?
Pulmonary hypertension: the hallmark of acute COVID-19 microvascular angiopathy? Open
In situ pulmonary arterial thrombosis in COVID-19 is not visible on CTPA. However, the presence of CT-measured right heart and pulmonary artery dilatation in COVID-19 is likely attributable to this process and may be a possible surrogate f…
View article: Persistent isolated impairment of gas transfer following COVID-19 pneumonitis relates to perfusion defects on dual-energy computed tomography
Persistent isolated impairment of gas transfer following COVID-19 pneumonitis relates to perfusion defects on dual-energy computed tomography Open
A novel iodine perfusion score correlates with breathlessness and D LCO in patients post-#COVID19 without obvious interstitial disease on CT, suggesting that lung perfusion assessment may be useful in patients without another cause of dysp…
View article: The authors reply
The authors reply Open
Singh, Suveer MD, PhD; Gorog, Diana A. MD, PhD, FRCP; Mahon, Ciara F. BCh, BAO, MSc, MRCP; Rawal, Bhavin MBBS, FRCR; Semple, Thomas R. FRCR; Nicol, Edward D. MD, FRCR; Arachchillage, Deepa R. J. MD, FRCPath; Price, Susanna PhD, FRCP; Desai…
View article: Corona Virus Disease 2019 <i>in situ</i> arterial and venous thrombosis in critically ill patients: a case series
Corona Virus Disease 2019 <i>in situ</i> arterial and venous thrombosis in critically ill patients: a case series Open
Background Corona Virus Disease 2019 (COVID-19) pneumonitis associated with severe respiratory failure carries a high mortality. Coagulopathy has emerged as a significant contributor to thrombotic complications. Case summary We describe tw…
View article: Use of lymphangiography in neonates prior to thoracic duct ligation
Use of lymphangiography in neonates prior to thoracic duct ligation Open
Congenital abnormalities or post-operative damage of the lymphatic system are rare causes of neonatal chylothorax or chylous ascites. Lymphangiography is a valuable tool for the diagnosis and treatment of lymphatic leaks and the assessment…
View article: Reply to Sanfilippo <i>et al.</i> and to Caviedes <i>et al.</i>
Reply to Sanfilippo <i>et al.</i> and to Caviedes <i>et al.</i> Open
the hypercoagulability state was mainly attributed to platelets and fibrin.Similarly, a recent study suggests that heparin treatment does not change mortality in severe COVID-19 cases (4).In contrast, a case series study suggests that tiss…
View article: Dual-Energy CT Pulmonary Angiography Quantifies Vasculopathy in Severe COVID-19 Pneumonia
Dual-Energy CT Pulmonary Angiography Quantifies Vasculopathy in Severe COVID-19 Pneumonia Open
Perfusion defects and decreased PBV/PAenh are prevalent in severe COVID-19 pneumonia. PBV/PAenh correlates with disease duration and inversely correlates with RVD. PBV/PAenh may be an important marker of vasculopathy in severe COVID-19 pne…
View article: When a multipolar catheter misses an “arm”: A known complication experienced anew
When a multipolar catheter misses an “arm”: A known complication experienced anew Open
Atrial arrhythmias are often encountered after cardiac surgery, with atrial fibrillation and atrial tachycardias (AT) being common early and late sequelae after operative mitral valve surgery. The mechanism of AT is most often macroreentry…
View article: Pulmonary Angiopathy in Severe COVID-19: Physiologic, Imaging, and Hematologic Observations
Pulmonary Angiopathy in Severe COVID-19: Physiologic, Imaging, and Hematologic Observations Open
Rationale: Clinical and epidemiologic data in coronavirus disease (COVID-19) have accrued rapidly since the outbreak, but few address the underlying pathophysiology.Objectives: To ascertain the physiologic, hematologic, and imaging basis o…
View article: Sequential screening for lung cancer in a high-risk group: randomised controlled trial
Sequential screening for lung cancer in a high-risk group: randomised controlled trial Open
Background Low-dose computed tomography (LDCT) screening detects early-stage lung cancer and reduces mortality. We proposed a sequential approach targeted to a high-risk group as a potentially efficient screening strategy. Methods LungSEAR…