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View article: British Cardiovascular Intervention Society Training Culture Focus Group Position Statement: Bringing Trainees and Trainers Together
British Cardiovascular Intervention Society Training Culture Focus Group Position Statement: Bringing Trainees and Trainers Together Open
Unprofessional behaviour within cardiology has been well documented and commonly occurs within the cardiac catheterisation laboratory, with higher rates in interventional subspecialities. While most trainees have positive experiences and e…
View article: Impeding LLM-assisted Cheating in Introductory Programming Assignments via Adversarial Perturbation
Impeding LLM-assisted Cheating in Introductory Programming Assignments via Adversarial Perturbation Open
While Large language model (LLM)-based programming assistants such as CoPilot and ChatGPT can help improve the productivity of professional software developers, they can also facilitate cheating in introductory computer programming courses…
View article: ASGARD risk scores for long-term, individualized cardiovascular surveillance of low-risk patients with asymptomatic non-severe aortic valve stenosis: development and internal validation
ASGARD risk scores for long-term, individualized cardiovascular surveillance of low-risk patients with asymptomatic non-severe aortic valve stenosis: development and internal validation Open
Background Routine echocardiography of asymptomatic patients with non-severe aortic valve stenosis (AS) mainly focuses on the valve condition at 1-2 year intervals but has limited ability to predict the risk of other cardiovascular comorbi…
View article: Validation of the developed ASGARD risk score for safe monitoring of asymptomatic patients with non-severe aortic valve stenosis
Validation of the developed ASGARD risk score for safe monitoring of asymptomatic patients with non-severe aortic valve stenosis Open
Background The recommended standard monitoring of patients with non-severe aortic valve stenosis (AS) involves echocardiography surveillance at 1-2 year intervals. Since many of these costly routine echocardiograms yield no clinical conseq…
View article: High-sensitive Troponin T is not associated with the progression of asymptomatic mild to moderate aortic stenosis: a post hoc substudy of the SEAS trial
High-sensitive Troponin T is not associated with the progression of asymptomatic mild to moderate aortic stenosis: a post hoc substudy of the SEAS trial Open
Background Aortic stenosis (AS) and coronary artery disease (CAD) share pathophysiological pathways, as reflected by frequent concomitant revascularization in patients undergoing aortic valve replacement (AVR). High-sensitive Troponin T (h…
View article: Networks for future healthcare
Networks for future healthcare Open
The Getting It Right First Time (GIRFT) process is designed to improve the care of patients in the NHS in England through in-depth review of services, benchmarking and presenting a data-driven evidence base to support change. It started as…
View article: United Kingdom standards for non-invasive cardiac imaging: recommendations from the Imaging Council of the British Cardiovascular Society
United Kingdom standards for non-invasive cardiac imaging: recommendations from the Imaging Council of the British Cardiovascular Society Open
Heart and circulatory diseases affect more than seven million people in the UK. Non-invasive cardiac imaging is a critical element of contemporary cardiology practice. Progressive improvements in technology over the last 20 years have incr…
View article: Joint British Societies’ guideline on management of cardiac arrest in the cardiac catheter laboratory
Joint British Societies’ guideline on management of cardiac arrest in the cardiac catheter laboratory Open
More than 300 000 procedures are performed in cardiac catheter laboratories in the UK each year. The variety and complexity of percutaneous cardiovascular procedures have both increased substantially since the early days of invasive cardio…
View article: Association of Annual N-Terminal Pro-Brain Natriuretic Peptide Measurements With Clinical Events in Patients With Asymptomatic Nonsevere Aortic Stenosis
Association of Annual N-Terminal Pro-Brain Natriuretic Peptide Measurements With Clinical Events in Patients With Asymptomatic Nonsevere Aortic Stenosis Open
ClinicalTrials.gov Identifier: NCT00092677.
View article: Copper chelation in patients with hypertrophic cardiomyopathy
Copper chelation in patients with hypertrophic cardiomyopathy Open
Background Disturbances of copper (Cu) homeostasis can lead to hypertrophic cardiac phenotypes (eg, Wilson’s disease). We previously identified abnormal Cu homeostasis in patients with hypertrophic cardiomyopathy (HCM) and, therefore, hypo…
View article: Uncovering the treatable burden of severe aortic stenosis in the UK
Uncovering the treatable burden of severe aortic stenosis in the UK Open
Objective To estimate the population prevalence and treatable burden of severe aortic stenosis (AS) in the UK. Methods We adapted a contemporary model of the population profile of symptomatic and asymptomatic severe AS in Europe and North …
View article: Bullying in UK cardiology: a systemic problem requiring systemic solutions
Bullying in UK cardiology: a systemic problem requiring systemic solutions Open
Objectives Bullying of trainee doctors has been shown to be associated with detrimental outcomes for both doctors and patients. However, there is limited evidence regarding the level of bullying of trainees within medical specialties. Meth…
View article: Professor Anthony H. Gershlick
Professor Anthony H. Gershlick Open
Interventional cardiology has lost one of its most prominent leaders, trainers, and researchers in Professor Tony Gershlick who died from COVID-19 on 20th November 2020 at the hospital he had worked in for over 30 years
View article: Prognostic impact of impaired left ventricular midwall function during progression of aortic stenosis
Prognostic impact of impaired left ventricular midwall function during progression of aortic stenosis Open
Objective In hypertension, indexes of midwall left ventricular (LV) function may identify patients at higher cardiovascular (CV) risk independent of normal LV ejection fraction (EF). We analyzed the association of baseline and new‐onset LV…
View article: Staphylococcus simulans endocarditis of native aortic and mitral valves. Case report and literature review
Staphylococcus simulans endocarditis of native aortic and mitral valves. Case report and literature review Open
Staphylococcus simulans is a coagulase-negative Staphylococcus species that is a commensal of domestic animals. We report the case of a 58 year old man with an aggressive form of S. simulans endocarditis involving native aortic and mitral …
View article: Physical exertion exacerbates decline in the musculature of an animal model of Duchenne muscular dystrophy
Physical exertion exacerbates decline in the musculature of an animal model of Duchenne muscular dystrophy Open
Significance Duchenne muscular dystrophy is a degenerative disease affecting tens of thousands of people in the United States alone. Much remains unknown about the disease, including the chain of events that links the loss of dystrophin to…
View article: MISSION: IMPOSSIBLE; The First Randomized Trial in Asymptomatic Patients with Severe Organic Mitral Valve Regurgitation
MISSION: IMPOSSIBLE; The First Randomized Trial in Asymptomatic Patients with Severe Organic Mitral Valve Regurgitation Open
One of the biggest controversies in valvular heart diseases is the best treatment strategy in asymptomatic patients with severe, organic mitral valve regurgitation (MR) and preserved left ventricular (LV) function. Current guidelines are c…
View article: SuPAR predicts postoperative complications and mortality in patients with asymptomatic aortic stenosis
SuPAR predicts postoperative complications and mortality in patients with asymptomatic aortic stenosis Open
Background We evaluated whether early measurement of soluble urokinase plasminogen activator receptor (suPAR) could predict future risk of postoperative complications in initially asymptomatic patients with mild-moderate aortic stenosis (A…
View article: Antihypertensive Treatment With β‐Blockade in Patients With Asymptomatic Aortic Stenosis and Association With Cardiovascular Events
Antihypertensive Treatment With β‐Blockade in Patients With Asymptomatic Aortic Stenosis and Association With Cardiovascular Events Open
Background Patients with aortic stenosis ( AS ) often have concomitant hypertension. Antihypertensive treatment with a β‐blocker (Bbl) is frequently avoided because of fear of depression of left ventricular function. However, it remains un…