Simon Uhse
YOU?
Author Swipe
View article: Tip of the iceberg? Three novel <scp>TOPLESS</scp>‐interacting effectors of the gall‐inducing fungus <i>Ustilago maydis</i>
Tip of the iceberg? Three novel <span>TOPLESS</span>‐interacting effectors of the gall‐inducing fungus <i>Ustilago maydis</i> Open
Summary Ustilago maydis is a biotrophic pathogen causing smut disease in maize. It secretes a cocktail of effector proteins, which target different host proteins during its biotrophic stages in the host plant. One such class of proteins we…
View article: Tip of the iceberg? Three novel TOPLESS interacting effectors of the gall-inducing fungus<i>Ustilago maydis</i>
Tip of the iceberg? Three novel TOPLESS interacting effectors of the gall-inducing fungus<i>Ustilago maydis</i> Open
Summary Ustilago maydis is a biotrophic pathogen causing smut disease in maize. It secretes a cocktail of effector proteins during its biotrophic stages in the host plant, which target different host proteins. One such class of proteins we…
View article: Tetracycline-controlled (TetON) gene expression system for the smut fungus Ustilago maydis
Tetracycline-controlled (TetON) gene expression system for the smut fungus Ustilago maydis Open
Ustilago maydis is a biotrophic phytopathogenic fungus that causes corn smut disease. As a well-established model system, U. maydis is genetically fully accessible with large omics datasets available and subject to various biological quest…
View article: Many ways to <scp>TOPLESS</scp> – manipulation of plant auxin signalling by a cluster of fungal effectors
Many ways to <span>TOPLESS</span> – manipulation of plant auxin signalling by a cluster of fungal effectors Open
Summary Plant biotrophic pathogens employ secreted molecules, called effectors, to suppress the host immune system and redirect the host's metabolism and development in their favour. Putative effectors of the gall‐inducing maize pathogenic…
View article: Ustilago maydis effector Jsi1 interacts with Topless corepressor, hijacking plant jasmonate/ethylene signaling
Ustilago maydis effector Jsi1 interacts with Topless corepressor, hijacking plant jasmonate/ethylene signaling Open
early access
View article: <i>Ustilago maydis</i> effector Jsi1 interacts with Topless corepressor, hijacking plant jasmonate/ethylene signaling
<i>Ustilago maydis</i> effector Jsi1 interacts with Topless corepressor, hijacking plant jasmonate/ethylene signaling Open
Summary Ustilago maydis is the causal agent of maize smut disease. During the colonization process, the fungus secretes effector proteins that suppress immune responses and redirect the host metabolism in favor of the pathogen. As effector…
View article: Fungal effector Jsi1 hijacks plant JA/ET signaling through Topless
Fungal effector Jsi1 hijacks plant JA/ET signaling through Topless Open
Ustilago maydis (U. maydis) is the causal agent of maize smut disease. During the colonization process, the fungus secretes effector proteins which suppress immune responses and redirect the host-metabolism in favor of the pathogen. Here w…
View article: Systematic Y2H Screening Reveals Extensive Effector-Complex Formation
Systematic Y2H Screening Reveals Extensive Effector-Complex Formation Open
During infection pathogens secrete small molecules, termed effectors, to manipulate and control the interaction with their specific hosts. Both the pathogen and the plant are under high selective pressure to rapidly adapt and co-evolve in …
View article: Insertion Pool Sequencing for Insertional Mutant Analysis in Complex Host‐Microbe Interactions
Insertion Pool Sequencing for Insertional Mutant Analysis in Complex Host‐Microbe Interactions Open
Insertional mutant libraries of microorganisms can be applied in negative depletion screens to decipher gene functions. Because of underrepresentation in colonized tissue, one major bottleneck is analysis of species that colonize hosts. To…
View article: Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3
Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3 Open
Translation termination requires eRF1 and eRF3 for polypeptide- and tRNA-release on stop codons. Additionally, Dbp5/DDX19 and Rli1/ABCE1 are required; however, their function in this process is currently unknown. Using a combination of in …
View article: Effectors of plant-colonizing fungi and beyond
Effectors of plant-colonizing fungi and beyond Open
Plant-microbe interactions have evolved over hundreds of millions of years, generating a diversity of interactions covering a broad continuum from pathogenic to mutualistic coexistence.Although these different lifestyles have different nee…
View article: The core effector Cce1 is required for early infection of maize by <i>Ustilago maydis</i>
The core effector Cce1 is required for early infection of maize by <i>Ustilago maydis</i> Open
The biotrophic pathogen Ustilago maydis , the causative agent of corn smut disease, infects one of the most important crops worldwide – Zea mays. To successfully colonize its host, U. maydis secretes proteins, known as effectors, that supp…
View article: In vivo insertion pool sequencing identifies virulence factors in a complex fungal–host interaction
In vivo insertion pool sequencing identifies virulence factors in a complex fungal–host interaction Open
Large-scale insertional mutagenesis screens can be powerful genome-wide tools if they are streamlined with efficient downstream analysis, which is a serious bottleneck in complex biological systems. A major impediment to the success of nex…
View article: A complete toolset for the study of Ustilago bromivora and Brachypodium sp. as a fungal-temperate grass pathosystem
A complete toolset for the study of Ustilago bromivora and Brachypodium sp. as a fungal-temperate grass pathosystem Open
Due to their economic relevance, the study of plant pathogen interactions is of importance. However, elucidating these interactions and their underlying molecular mechanisms remains challenging since both host and pathogen need to be fully…
View article: Author response: A complete toolset for the study of Ustilago bromivora and Brachypodium sp. as a fungal-temperate grass pathosystem
Author response: A complete toolset for the study of Ustilago bromivora and Brachypodium sp. as a fungal-temperate grass pathosystem Open
Article Figures and data Abstract eLife digest Introduction Results and Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Due to their economic rel…