Explanipedia

131 Rare Consequences of a Common Event: Post-seizure Cervical Chyle Leak Complicated by Bilateral Chylothorax in a Young Woman Open

C. Lawrence, Charles A. Riley, Christopher Huntley, Alexander Holden, S Lihony , et al. · 2025

A woman in her thirties presented with an acute onset painful neck swelling and tracheal deviation. Despite multiple imaging modalities, a diagnosis was not reached until a pleural tap revealed an atraumatic chylothorax after MRI showed bi…

The Impact of Pathological Margins on Basal Cell Carcinoma Recurrence: Does a Millimetre Matter? Open

Shahd Nour, Dalia Mohamed, Ouali Braham, Simon Wharton · 2025

Background Basal cell carcinoma (BCC) is the most common skin malignancy worldwide. Existing studies on histopathological margins and recurrence have lacked long-term follow-up and histopathological confirmation, leaving no clear consensus…

Effect of obstructive sleep apnoea on retinal microvascular function: a randomised controlled trial Open

Chris D. Turnbull, James Stockley, Shyam Madathil, Syed Huq, Brendan Cooper , et al. · 2022

Development and Relevance of Hypercapnia in COPD Open

Chirag Dave, Simon Wharton, Rahul Mukherjee, Bandar M. Faqihi, Robert A. Stockley , et al. · 2021

Background. Identification of patients who may become hypercapnic, or develop acidotic hypercapnic respiratory failure (AHRF), is important in chronic obstructive pulmonary disease (COPD) to avoid hospital admission and select patients for…

Should awake proning be used before continuous positive airway pressure therapy for respiratory support in COVID pneumonia Open

Arun Khanna, Milind Sovani, Dipansu Gosh, Ben Messer, Simon Wharton · 2020

As of May 31, 2020, there are 5,934,936 confirmed cases of COVID-19 with 367,166 deaths. This pandemic has placed a severe strain on intensive care units (ICUs) with demand outstripping capacity. At the start of the pandemic, early intubat…

Does Continuous Positive Airway Pressure (CPAP) treatment of obstructive sleep apnoea (OSA) improve asthma-related clinical outcomes in patients with co-existing conditions?- A systematic review Open

Sarah Davies, Abigail Bishopp, Simon Wharton, Alice Turner, Adel Mansur · 2018

P202 Obstructive sleep apnoea (osa) and non-eosinophilic asthma: an important phenotype in the severe asthma population Open

Sarah L. Davies, N Cachada, Alice Turner, Simon Wharton, A Mansur · 2017

Introduction An association between Obstructive Sleep Apnoea (OSA) and asthma has been suggested, with OSA adversely impacting on clinical outcomes. The importance of OSA in severe asthma, and understanding of this phenotype in relation to…

P195 “syndrome z” in the asthma population Open

Sarah L. Davies, N Cachada, Simon Wharton, Alice Turner, Adel Mansur · 2017

Introduction Current literature demonstrates associations between asthma, obstructive sleep apnoea (OSA) and obesity. Syndrome Z is the occurrence of OSA with the metabolic syndrome, and the relevance of this condition in asthma population…

M9 A high prevalence of obstructive sleep apnoea (OSA) in the severe/difficult to treat asthma (SDTA) population Open

SE Davies, N Cachada, Alice Turner, Simon Wharton, Adel Mansur · 2016

Introduction An association between OSA and asthma has been demonstrated. The exact prevalence in the SDTA population is unknown. Aim To determine the prevalence and predictors of OSA in the SDTA population Methods All patients who attende…

Systemic inflammatory disease resolution following cosmetic silicone breast implant removal Open

Sue Ann Chan, Feryal Malik, Simon Wharton, Rainer Klocke · 2015

A 37-year-old Caucasian woman presented with subacute, symmetrical inflammatory arthralgia, which was affecting her work. Apart from fatigue, she had no other constitutional symptoms. She had undergone cosmetic bilateral silicone breast im…

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