Explanipedia

Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators Open

Lindsay D. Nelson, Brooke E. Magnus, John K. Yue, Steve Balsis, Christopher J. Patrick , et al. · 2025

This secondary analysis project was funded by the U.S. National Institute of Neurological Disorders and Stroke (Grant No. R01 NS110856).

TILTomorrow today: dynamic factors predicting changes in intracranial pressure treatment intensity after traumatic brain injury Open

Shubhayu Bhattacharyay, Florian D. van Leeuwen, Erta Beqiri, Cecilia Åkerlund, Lindsay Wilson , et al. · 2025

Non-Technical Skills in Neurosurgery: A Key To Success Open

Simona Cavallo, Giovanni Carone, Elisa Pellencin, Nicolò Castelli, Aliasgar Moiyadi , et al. · 2025

Early versus delayed cranioplasty after decompressive craniectomy in traumatic brain injury: a multicenter observational study within CENTER-TBI and Net-QuRe Open

Rick Vreeburg, Ranjit D. Singh, Inge A. M. van Erp, Tommi K. Korhonen, John K. Yue , et al. · 2024

OBJECTIVE The aim of this study was to compare the outcomes of early (≤ 90 days) and delayed (> 90 days) cranioplasty following decompressive craniectomy (DC) in patients with traumatic brain injury (TBI). METHODS The authors analyzed part…

Frequency and predictors of headache in the first 12 months after traumatic brain injury: results from CENTER-TBI Open

Emilie Isager Howe, Nada Anđelić, Cathrine Brunborg, Marina Zeldovich, Eirik Helseth , et al. · 2024

Early vs Late Fixation of Extremity Fractures Among Adults With Traumatic Brain Injury Open

Zheng Jiang, Yufang Ouyang, Ke Zhang, Zhixing Wang, Alexander Younsi , et al. · 2024

Importance The optimal timing for fixation of extremity fractures after traumatic brain injury (TBI) remains controversial. Objective To investigate whether patients who underwent extremity fixation within 24 hours of TBI experienced worse…

Early systemic insults following traumatic brain injury: association with biomarker profiles, therapy for intracranial hypertension, and neurological outcomes—an analysis of CENTER-TBI data Open

Chiara Robba, Francesca Graziano, Edoardo Picetti, Cecilia Åkerlund, Alberto Addis , et al. · 2024

Though less frequent than previously described, SIs in TBI patients are associated with higher release of neuronal than glial injury biomarkers and with increased requirements for ICU therapies aimed at reducing intracranial hypertension. …

Contrasting Characteristics and Outcomes of Sports-Related and Non–Sports-Related Traumatic Brain Injury Open

Michail Ntikas, William Stewart, Magdalena Ietswaart, Angus M. Hunter, Andrew I.R. Maas , et al. · 2024

Importance Exposure to traumatic brain injury (TBI) has raised widespread concern over participation in sports, particularly over possible long-term consequences. However, little is known about the outcomes of individuals presenting to hos…

Non-technical skills for neurosurgeons: An international survey Open

Simona Cavallo, Elisa Pellencin, Giovanni Carone, Nicolò Castelli, Roberta Ayadi , et al. · 2024

Clinical descriptors of disease trajectories in patients with traumatic brain injury in the intensive care unit (CENTER-TBI): a multicentre observational cohort study Open

Cecilia Åkerlund, Anders Vedel Holst, Shubhayu Bhattacharyay, Nino Stocchetti, Ewout W. Steyerberg , et al. · 2023

Factorial validity and comparability of the six translations of the Rivermead Post-Concussion Symptoms Questionnaire translations: results from the CENTER-TBI study Open

Marina Zeldovich, Fabian Bockhop, Amra Čović, Isabelle Mueller, Suzanne Polinder , et al. · 2023

Comparative effectiveness of decompressive craniectomy versus craniotomy for traumatic acute subdural hematoma (CENTER-TBI): an observational cohort study Open

Thomas A. van Essen, Inge A. M. van Erp, Hester F. Lingsma, Dana Pisică, John K. Yue , et al. · 2023

Correction: High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI Open

Emanuele Rezoagli, Matteo Petrosino, Paola Rebora, David K. Menon, Stefania Mondello , et al. · 2023

Computed Tomography Lesions and Their Association With Global Outcome in Young People With Mild Traumatic Brain Injury Open

Lennart Riemann, Ana Mikolić, Andrew I.R. Maas, Andreas Unterberg, Alexander Younsi , et al. · 2022

Mild traumatic brain injury (mTBI) can be accompanied by structural damage to the brain. Here, we investigated how the presence of intracranial traumatic computed tomography (CT) pathologies relates to the global functional outcome in youn…

Rehabilitation and outcomes after complicated vs uncomplicated mild TBI: results from the CENTER-TBI study Open

Emilie Isager Howe, Marina Zeldovich, Nada Anđelić, Nicole von Steinbüechel, Silje C. R. Fure , et al. · 2022

Background Despite existing guidelines for managing mild traumatic brain injury (mTBI), evidence-based treatments are still scarce and large-scale studies on the provision and impact of specific rehabilitation services are needed. This stu…

High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI Open

Emanuele Rezoagli, Matteo Petrosino, Paola Rebora, David K. Menon, Stefania Mondello , et al. · 2022

Measurement invariance of six language versions of the post-traumatic stress disorder checklist for DSM-5 in civilians after traumatic brain injury Open

Fabian Bockhop, Marina Zeldovich, Katrin Cunitz, Dominique Van Praag, Marjolein van der Vlegel , et al. · 2022

Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study Open

Cecilia Åkerlund, Anders Vedel Holst, Nino Stocchetti, Ewout W. Steyerberg, David K. Menon , et al. · 2022

Comparative effectiveness of intracranial hypertension management guided by ventricular versus intraparenchymal pressure monitoring: a CENTER-TBI study Open

Victor Volovici, Dana Pisică, Benjamin Gravesteijn, Clemens M.F. Dirven, Ewout W. Steyerberg , et al. · 2022

Health care utilization and outcomes in older adults after Traumatic Brain Injury: A CENTER-TBI study Open

Marjolein van der Vlegel, Ana Mikolić, Quentin Lee Hee, Z Kaplan, Isabel R. A. Retel Helmrich , et al. · 2022

Tailoring Multi-Dimensional Outcomes to Level of Functional Recovery after Traumatic Brain Injury Open

Lindsay Wilson, Lindsay Horton, Suzanne Polinder, Virginia Newcombe, Nicole von Steinbüechel , et al. · 2022

There is increasing emphasis on assessing multi-dimensional outcomes in traumatic brain injury (TBI), but achieving this aim is hampered by a plethora of overlapping assessment tools. There is a clear need for advice on the choice of outco…

Serum metabolome associated with severity of acute traumatic brain injury Open

Ilias Thomas, Alex M. Dickens, Jussi P. Posti, Endre Czeiter, Daniel Duberg , et al. · 2022

Surgery versus conservative treatment for traumatic acute subdural haematoma: a prospective, multicentre, observational, comparative effectiveness study Open

Thomas A. van Essen, Hester F. Lingsma, Dana Pisică, Ranjit D. Singh, Victor Volovici , et al. · 2022

Vibrational Spectroscopy for the Triage of Traumatic Brain Injury Computed Tomography Priority and Hospital Admissions Open

Ashton G. Theakstone, Paul M. Brennan, Katherine M. Ashton, Endre Czeiter, Michael D. Jenkinson , et al. · 2022

Computed tomography (CT) brain imaging is routinely used to support clinical decision-making in patients with traumatic brain injury (TBI). Only 7% of scans, however, demonstrate evidence of TBI. The other 93% of scans contribute a signifi…

A genome-wide association study of outcome from traumatic brain injury Open

Mart Kals, Kevin Kunzmann, Livia Parodi, Farid Radmanesh, Lindsay Wilson , et al. · 2022

Effect of frailty on 6-month outcome after traumatic brain injury: a multicentre cohort study with external validation Open

Stefania Galimberti, Francesca Graziano, Andrew I.R. Maas, Giulia Isernia, Fiona Lecky , et al. · 2022

Neurocognitive correlates of probable posttraumatic stress disorder following traumatic brain injury Open

Dominique Van Praag, Kristien Wouters, Filip Van Den Eede, Cecilia Åkerlund, Krisztina Amrein , et al. · 2021

Extended Coagulation Profiling in Isolated Traumatic Brain Injury: A CENTER-TBI Analysis Open

Julia K. Böhm, Victoria Schaeben, Nadine Schäfer, Helge Güting, Rolf Lefering , et al. · 2021

Can We Cluster ICU Treatment Strategies for Traumatic Brain Injury by Hospital Treatment Preferences? Open

Iris Ceyisakar, Jilske Huijben, Andrew I.R. Maas, Hester F. Lingsma, Nikki van Leeuwen , et al. · 2021

Explaining Outcome Differences between Men and Women following Mild Traumatic Brain Injury Open

Ana Mikolić, Joost Oude Groeniger, Marina Zeldovich, Lindsay Wilson, Jeanine E. Roeters van Lennep , et al. · 2021

Men and women differ in outcomes following mild traumatic brain injury (TBI). In the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study, we previously found that women had worse 6-month f…

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