Simona Langner
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View article: Trans-bronchial forceps biopsy for COVID-19 related diffuse parenchymal lung abnormalities
Trans-bronchial forceps biopsy for COVID-19 related diffuse parenchymal lung abnormalities Open
View article: IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota
IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota Open
IL-22 plays a critical role in defending against mucosal infections, but how IL-22 production is regulated is incompletely understood. Here, we show that mice lacking IL-33 or its receptor ST2 (IL-1RL1) were more resistant to Streptococcus…
View article: Impaired diaphragmatic motility in treatment‐naive adult patients with spinal muscular atrophy improved during nusinersen treatment
Impaired diaphragmatic motility in treatment‐naive adult patients with spinal muscular atrophy improved during nusinersen treatment Open
Introduction/Aims The leading clinical feature of 5q‐associated spinal muscular atrophy (SMA) is symmetric, proximal muscle weakness. Muscles involved in ventilation exhibit a specific pattern of denervation: intercostal muscles are severe…
View article: Affection of Respiratory Muscles in ALS and SMA
Affection of Respiratory Muscles in ALS and SMA Open
Respiratory dysfunction is a common cause of morbidity and mortality in motor neuron disease (MND). However, classical volitional measures of respiratory function in these patients are impeded by, e.g., bulbar paralysis or progressive disa…