Simona Luzzi
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View article: International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative
International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative Open
This is the first focused endeavor to favor the implementation of socio-cognitive assessment, which is required by DSM-5 but seldom performed despite clear evidence of its clinical relevance for diagnosis and care. Our results provide an i…
View article: Correction: Luzzi et al. Defective Awareness of Person-Recognition Disorders Through Face, Voice and Name in Right and Left Variants of Semantic Dementia: A Pilot Study. Brain Sci. 2025, 15, 504
Correction: Luzzi et al. Defective Awareness of Person-Recognition Disorders Through Face, Voice and Name in Right and Left Variants of Semantic Dementia: A Pilot Study. Brain Sci. 2025, 15, 504 Open
In the original publication [...]
View article: Defective Awareness of Person-Recognition Disorders Through Face, Voice and Name in Right and Left Variants of Semantic Dementia: A Pilot Study
Defective Awareness of Person-Recognition Disorders Through Face, Voice and Name in Right and Left Variants of Semantic Dementia: A Pilot Study Open
Background/Objectives: The aim of this investigation consisted of evaluating if the prevalence of anosognosia in right-brain-damaged patients is greater for tasks in which the right hemisphere plays a dominant role and if this prevalence i…
View article: Multi-Class Detection of Neurodegenerative Diseases from EEG Signals Using Lightweight LSTM Neural Networks
Multi-Class Detection of Neurodegenerative Diseases from EEG Signals Using Lightweight LSTM Neural Networks Open
Neurodegenerative diseases severely impact the life of millions of patients worldwide, and their occurrence is more and more increasing proportionally to longer life expectancy. Electroencephalography has become an important diagnostic too…
View article: Transcranial direct current stimulation in semantic variant of primary progressive aphasia: a state-of-the-art review
Transcranial direct current stimulation in semantic variant of primary progressive aphasia: a state-of-the-art review Open
The semantic variant of primary progressive aphasia (svPPA), known also as “semantic dementia (SD),” is a neurodegenerative disorder that pertains to the frontotemporal lobar degeneration clinical syndromes. There is currently no approved …
View article: A Deep Learning Model for Correlation Analysis between Electroencephalography Signal and Speech Stimuli
A Deep Learning Model for Correlation Analysis between Electroencephalography Signal and Speech Stimuli Open
In recent years, the use of electroencephalography (EEG) has grown as a tool for diagnostic and brain function monitoring, being a simple and non-invasive method compared with other procedures like histological sampling. Typically, in orde…
View article: The Dynamic Interplay between Loss of Semantic Memory and Semantic Learning Capacity: Insight from Neologisms Learning in Semantic Variant Primary Progressive Aphasia
The Dynamic Interplay between Loss of Semantic Memory and Semantic Learning Capacity: Insight from Neologisms Learning in Semantic Variant Primary Progressive Aphasia Open
Semantic Variant of Primary Progressive Aphasia (svPPA) has often been considered as a loss of knowledge stored in semantic memory, but might also be due to a general disruption of mechanisms allowing the acquisition, storage, and retrieva…
View article: Apperceptive and Associative Forms of Phonagnosia
Apperceptive and Associative Forms of Phonagnosia Open
Purpose of Review Pronagnosia is a rare acquired or developmental pathological condition that consists of a selective difficulty to recognize familiar people by their voices. It can be distinguished into two different categories: appercept…
View article: Multiple Sclerosis: Inflammatory and Neuroglial Aspects
Multiple Sclerosis: Inflammatory and Neuroglial Aspects Open
Multiple sclerosis (MS) represents the most common acquired demyelinating disorder of the central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of mechanisms pertaining to autoimmunity, involves several…
View article: Exploring the Interaction between Fractional Exhaled Nitric Oxide and Biologic Treatment in Severe Asthma: A Systematic Review
Exploring the Interaction between Fractional Exhaled Nitric Oxide and Biologic Treatment in Severe Asthma: A Systematic Review Open
Background: Fractional exhaled nitric oxide (FeNO) is a biomarker of airway inflammation associated with airway hyper-responsiveness and type-2 inflammation. Its role in the management of severe asthmatic patients undergoing biologic treat…
View article: Homocysteine, Cognitive Functions, and Degenerative Dementias: State of the Art
Homocysteine, Cognitive Functions, and Degenerative Dementias: State of the Art Open
There is strong evidence that homocysteine is a risk factor not only for cerebrovascular diseases but also for degenerative dementias. A recent consensus statement renewed the importance and the role of high levels of homocysteine in cogni…
View article: EEG-Based Alzheimer’s Disease Recognition Using Robust-PCA and LSTM Recurrent Neural Network
EEG-Based Alzheimer’s Disease Recognition Using Robust-PCA and LSTM Recurrent Neural Network Open
The use of electroencephalography (EEG) has recently grown as a means to diagnose neurodegenerative pathologies such as Alzheimer’s disease (AD). AD recognition can benefit from machine learning methods that, compared with traditional manu…
View article: Shared Molecular Mechanisms among Alzheimer’s Disease, Neurovascular Unit Dysfunction and Vascular Risk Factors: A Narrative Review
Shared Molecular Mechanisms among Alzheimer’s Disease, Neurovascular Unit Dysfunction and Vascular Risk Factors: A Narrative Review Open
Alzheimer’s disease (AD) is the most common type of dementia, affecting 24 million individuals. Clinical and epidemiological studies have found several links between vascular risk factors (VRF), neurovascular unit dysfunction (NVUd), blood…
View article: Cerebrospinal Fluid α-Calcitonin Gene-Related Peptide: A Comparison between Alzheimer’s Disease and Multiple Sclerosis
Cerebrospinal Fluid α-Calcitonin Gene-Related Peptide: A Comparison between Alzheimer’s Disease and Multiple Sclerosis Open
Alzheimer’s disease (AD) and Multiple Sclerosis (MS) represent an emerging health problem on a global scale, as they are responsible for a significant contribution to the burden of disability in Western countries. Limited numbers of cerebr…
View article: Vasoactive neuropeptides and Alzheimer’s disease: a systematic review focusing on calcitonin gene-related peptide
Vasoactive neuropeptides and Alzheimer’s disease: a systematic review focusing on calcitonin gene-related peptide Open
Vasoactive peptides constitute a heterogenous family of mediators exerting various physiological functions, mostly studied for their vasotropic effects and role as peripheral neurotransmitters/neuromodulators, mainly involved in nociceptiv…
View article: Cytokine Profiles in the Detection of Severe Lung Involvement in Hospitalized Patients With COVID-19: the IL-8 – IL-32 axis
Cytokine Profiles in the Detection of Severe Lung Involvement in Hospitalized Patients With COVID-19: the IL-8 – IL-32 axis Open
Coronavirus disease 2019 (COVID-19) is an infectious respiratory disorder caused by a new coronavirus called SARS-CoV-2. The pathophysiology of severe COVID-19 is associated with a “cytokine storm”, characterized by anomalous release of va…
View article: Classification of Alzheimer’s Disease from EEG Signal Using Robust-PCA Feature Extraction
Classification of Alzheimer’s Disease from EEG Signal Using Robust-PCA Feature Extraction Open
The encephalographic (EEG) signal is an electrical signal that measures the brain activity. Due to its noninvasive acquisition process, it is often used to investigate the presence of Alzheimer’s disease (AD) or other common forms of neuro…
View article: Item consistency in retrieving person-specific semantic information from faces and voices: An exploratory study in healthy subjects
Item consistency in retrieving person-specific semantic information from faces and voices: An exploratory study in healthy subjects Open
Controversies exist over the format of person-specific semantic representations in healthy subjects and the loss of part of these representations in conditions of brain pathology. Some authors have suggested that in brain-damaged patients …