Simona Piccinini
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View article: Real-Time Dose Monitoring via Non-Destructive Charge Measurement of Laser-Driven Electrons for Medical Applications
Real-Time Dose Monitoring via Non-Destructive Charge Measurement of Laser-Driven Electrons for Medical Applications Open
Laser-accelerated electron beams, in the so-called Very High-Energy Electron (VHEE) energy range, are of great interest for biomedical applications. For instance, laser-driven VHEE beams are envisaged to offer suitable compact accelerators…
View article: Radionuclide Production for Dose Verification in VHEE FLASH Radiotherapy
Radionuclide Production for Dose Verification in VHEE FLASH Radiotherapy Open
This study explores the production of radionuclides in a PMMA (Polymethylmethacrylate) phantom irradiated with Very High Energy Electrons (VHEE) beams as a novel method for dose verification. In this work, Monte Carlo simulation studies us…
View article: Very High-Energy Electron Therapy Toward Clinical Implementation
Very High-Energy Electron Therapy Toward Clinical Implementation Open
The use of very high energy electron (VHEE) beams, with energies between 50 and 400 MeV, has drawn considerable interest in radiotherapy due to their deep tissue penetration, sharp beam edges, and low sensitivity to tissue density. VHEE be…
View article: Very High-Energy Electron Therapy Toward Clinical Implementation: A Review Study
Very High-Energy Electron Therapy Toward Clinical Implementation: A Review Study Open
The use of Very High Energy Electron (VHEE) beams, with energies between 50 and 400 MeV, has drawn considerable interest in radiotherapy due to their deep tissue penetration, sharp beam edges, and low sensitivity to tissue density. VHEE be…
View article: FLASH Radiotherapy: Expectations, Challenges, and Current Knowledge
FLASH Radiotherapy: Expectations, Challenges, and Current Knowledge Open
Major strides have been made in the development of FLASH radiotherapy (FLASH RT) in the last ten years, but there are still many obstacles to overcome for transfer to the clinic to become a reality. Although preclinical and first-in-human …
View article: Correction: Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D
Correction: Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D Open
[This corrects the article DOI: 10.1371/journal.pone.0157962.].
View article: Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D
Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D Open
[This corrects the article DOI: 10.1371/journal.pone.0157962.].
View article: Type 1 Diabetes at-risk children highly recognize Mycobacterium avium subspecies paratuberculosis epitopes homologous to human Znt8 and Proinsulin
Type 1 Diabetes at-risk children highly recognize Mycobacterium avium subspecies paratuberculosis epitopes homologous to human Znt8 and Proinsulin Open
Mycobacterium avium subspecies paratuberculosis (MAP) has been previously associated to T1D as a putative environmental agent triggering or accelerating the disease in Sardinian and Italian populations. Our aim was to investigate the role …