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View article: Spermatogonial Stem Cells in Domestic Animals: Current Insights and Future Directions with a Focus on Dogs
Spermatogonial Stem Cells in Domestic Animals: Current Insights and Future Directions with a Focus on Dogs Open
The growing interest in improving the fertility-rate of livestock species, considering their high economic value, has prompted the development of new methodological approaches using male germline stem cells. Spermatogonial stem cells’ (SSC…
View article: Recombinant NK1 Protein and LEDs: An Innovative Strategy to Counteract Resistant Staphylococcus pseudintermedius and Pseudomonas aeruginosa Strains
Recombinant NK1 Protein and LEDs: An Innovative Strategy to Counteract Resistant Staphylococcus pseudintermedius and Pseudomonas aeruginosa Strains Open
The increase in multi-drug-resistant strains represents a global challenge that strongly underlines the importance of the search for new eco-sustainable strategies. The aim of this work was to suggest a non-antibiotic approach to counterac…
View article: Cathepsin B Levels Correlate with the Severity of Canine Myositis
Cathepsin B Levels Correlate with the Severity of Canine Myositis Open
Cathepsins are protease enzymes vital for normal physiological functions, such as digestion, coagulation, hormone secretion, bone resorption, apoptosis, autophagy, and both innate and adaptive immunity. Their altered expression and/or acti…
View article: Assessment of Oxidative Stress and Biometric Data in a Captive Colony of Hamadryas Baboons (Papio hamadryas Linnaeus, 1758) at the Ravenna Zoo Safari (Italy)
Assessment of Oxidative Stress and Biometric Data in a Captive Colony of Hamadryas Baboons (Papio hamadryas Linnaeus, 1758) at the Ravenna Zoo Safari (Italy) Open
This study evaluates the health of a captive colony of Hamadryas baboons at Ravenna Zoo Safari (Italy), focusing on oxidative stress markers and biometric data. Forty-eight individuals were assessed during routine veterinary procedures: ma…
View article: Assessing Bottlenose Dolphins’ (Tursiops truncatus) Health Status Through Functional Muscle Analysis, and Oxidative and Metabolic Stress Evaluation: A Preliminary Study
Assessing Bottlenose Dolphins’ (Tursiops truncatus) Health Status Through Functional Muscle Analysis, and Oxidative and Metabolic Stress Evaluation: A Preliminary Study Open
Oxidative stress (OS) occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the body’s antioxidant defenses, causing damage to lipids, proteins, and DNA. In marine mammals, physiological adaptation t…
View article: G Protein-Coupled Estrogen Receptor (GPER) and ERs Are Modulated in the Testis–Epididymal Complex in the Normal and Cryptorchid Dog
G Protein-Coupled Estrogen Receptor (GPER) and ERs Are Modulated in the Testis–Epididymal Complex in the Normal and Cryptorchid Dog Open
There is growing evidence by the literature that the unbalance between androgens and estrogens is a relevant condition associated with a common canine reproductive disorder known as cryptorchidism. The role of estrogens in regulating testi…
View article: Maca (Lepidium meyenii): In Vitro Evaluation of Rumen Fermentation and Oxidative Stress
Maca (Lepidium meyenii): In Vitro Evaluation of Rumen Fermentation and Oxidative Stress Open
The aim of this study was to investigate the chemical composition of three maca (Lepidium meyenii Walp.) ecotypes (yellow, black, and red) and their in vitro fermentation characteristics and antioxidant effects on cow rumen liquor. The thr…
View article: Evaluation of Muscle Proteins for Estimating the Post-Mortem Interval in Veterinary Forensic Pathology
Evaluation of Muscle Proteins for Estimating the Post-Mortem Interval in Veterinary Forensic Pathology Open
Postmortem cadaveric changes are commonly used to estimate the postmortem interval (PMI) in humans and animals. However, these modifications have been poorly investigated in animals of interest to veterinary forensic pathology. The aim of …
View article: The Key Role of Lysosomal Protease Cathepsins in Viral Infections
The Key Role of Lysosomal Protease Cathepsins in Viral Infections Open
Cathepsins encompass a family of lysosomal proteases that mediate protein degradation and turnover. Although mainly localized in the endolysosomal compartment, cathepsins are also found in the cytoplasm, nucleus, and extracellular space, w…
View article: Effect of Aqueous Extract of Maca Addition to an Extender for Chilled Canine Semen
Effect of Aqueous Extract of Maca Addition to an Extender for Chilled Canine Semen Open
Antioxidant supplementation has been proposed as a new strategy to improve the long-term preservation of semen. The aim of this study was to evaluate the effect of Maca supplementation of semen extender on quality-related canine semen para…
View article: Effects of Oral Administration of Lepidium meyenii on Morphology of Mice Testis and Motility of Epididymal Sperm Cells After Tetrahydrocannabinol Exposure
Effects of Oral Administration of Lepidium meyenii on Morphology of Mice Testis and Motility of Epididymal Sperm Cells After Tetrahydrocannabinol Exposure Open
Background: Tetrahydrocannabinol (THC) administration is associated with testicular damage and reduced semen quality. Oral administration of Lepidium Meyenii (maca) improves spermatogenesis and sperm motility and count and reduces spermato…
View article: Heparan Sulfate Proteoglycans in Viral Infection and Treatment: A Special Focus on SARS-CoV-2
Heparan Sulfate Proteoglycans in Viral Infection and Treatment: A Special Focus on SARS-CoV-2 Open
Heparan sulfate proteoglycans (HSPGs) encompass a group of glycoproteins composed of unbranched negatively charged heparan sulfate (HS) chains covalently attached to a core protein. The complex HSPG biosynthetic machinery generates an extr…
View article: Antioxidants in assisted reproductive technologies: An overview on dog, cat, and horse
Antioxidants in assisted reproductive technologies: An overview on dog, cat, and horse Open
Assisted reproductive technologies (ARTs) are widely used as a tool to improve reproductive performance in both humans and animals. In particular, in the veterinary field, ARTs are used to improve animal genetics, recover endangered animal…
View article: Human-Animal Relationship Dysfunction: A Case Study of Animal Hoarding in Italy
Human-Animal Relationship Dysfunction: A Case Study of Animal Hoarding in Italy Open
“Animal hoarding” or “compulsive hoarding of animals” is a psychiatric disease, which has important social implications and a profound influence on animal welfare. To date, this phenomenon has been little investigated and largely unexplore…
View article: Antioxidant supplementation to medium for in vitro embryo production in Felis catus
Antioxidant supplementation to medium for in vitro embryo production in Felis catus Open
The development of in vitro embryo production (IVEP) techniques in Felis catus is a fitting model with potential application to the conservation of endangered felid species. To improve the quality of IVEP techniques an appropriate balance …
View article: Chemical Analysis of Lepidium meyenii (Maca) and Its Effects on Redox Status and on Reproductive Biology in Stallions
Chemical Analysis of Lepidium meyenii (Maca) and Its Effects on Redox Status and on Reproductive Biology in Stallions Open
The present study was conducted to assess the chemical composition of Yellow Maca (Lepidium meyenii) and its biological activity on stallions following oral administration of hypocotyl powder. Maca was subjected to methanolic extraction an…
View article: Reactive oxygen metabolitesin alpha-herpesvirus-seropositive Mediterranean buffaloes (Bubalus bubalis): a preliminary study
Reactive oxygen metabolitesin alpha-herpesvirus-seropositive Mediterranean buffaloes (Bubalus bubalis): a preliminary study Open
In the present study on Bubalus bubalis of the Campania Region (Italy) the serum levels of derivatives of reactive oxygen metabolites (d-ROMs), anti-ROM and oxidative stress index (Osi) were evaluated. These data were then related to the s…
View article: Influences of dietary supplementation with <i>Lepidium meyenii</i> (Maca) on stallion sperm production and on preservation of sperm quality during storage at 5 °C
Influences of dietary supplementation with <i>Lepidium meyenii</i> (Maca) on stallion sperm production and on preservation of sperm quality during storage at 5 °C Open
Summary Stallion semen is damaged by oxidative stress during cooling and transport. Semen processing and extenders have been tested to improve the fertilizing capacity of semen and to preserve semen during transport. Dietary supplementatio…
View article: Functional Aspects of Lepidium meyenii (Maca) Diet Integration
Functional Aspects of Lepidium meyenii (Maca) Diet Integration Open
Lepidium meyenii (Maca) is an edible root plant, belonging to the Brassicaceae family, found in the Andean regions of Peru. It is sold as a nutritional supplement and is gaining as a botanical extract for, among other things, its enhanceme…
View article: Effect of superoxide dismutase, catalase, and glutathione peroxidase supplementation in the extender on chilled semen of fertile and hypofertile dogs
Effect of superoxide dismutase, catalase, and glutathione peroxidase supplementation in the extender on chilled semen of fertile and hypofertile dogs Open
This study investigated the correlation between oxidative stress status and key canine sperm parameters and the effect of addition of a superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) combination in egg yolk tr…
View article: The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease
The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease Open
Kidney disease is worldwide the 12th leading cause of death affecting 8-16% of the entire population. Kidney disease encompasses acute (short-lasting episode) and chronic (developing over years) pathologies both leading to renal failure. S…
View article: Redoxomics and Oxidative Stress: From the Basic Research to the Clinical Practice
Redoxomics and Oxidative Stress: From the Basic Research to the Clinical Practice Open
Potentially oxidant chemical species, which include not only free radicals but also other oxidizing chemical species such as reactive oxygen species (ROS), for example, hydroxyl radical and hydrogen peroxide, and nitrogen reactive species …
View article: Expression of orexin B and its receptor 2 in rat testis
Expression of orexin B and its receptor 2 in rat testis Open
View article: Reactive Oxygen Species (ROS) and Male Fertility
Reactive Oxygen Species (ROS) and Male Fertility Open
Oxidative energy production is inevitably associated with the generation of reactive oxygen species (ROS), excessive concentrations of which can lead to cellular pathology. A free radical may be defined as any molecule that has one or more…
View article: Assisted Reproductive Technologies in Safeguard of Feline Endangered Species
Assisted Reproductive Technologies in Safeguard of Feline Endangered Species Open
The growth of the human population and the escalating consumption of natural resources have reduced wild habitats, modifying the existing balance of biological cycles. Therefore, ex situ conservation efforts have received renewed attention…