Simone Arosio
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Author Swipe
View article: A trifunctional self-immolative spacer enables drug release with two non-sequential enzymatic cleavages
A trifunctional self-immolative spacer enables drug release with two non-sequential enzymatic cleavages Open
The enzymatic dephosphorylation of a self-immolative spacer accelerates cargo release and acts as an additional and independent trigger in protease-sensitive prodrugs.