Simone Kienle
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View article: Random birth order and bursty Notch ligand expression drive the stochastic AC/VU cell fate decision in<i>C. elegans</i>
Random birth order and bursty Notch ligand expression drive the stochastic AC/VU cell fate decision in<i>C. elegans</i> Open
Cells in developing organisms must robustly assume the correct fate in order to fulfill their specific function. At the same time, cells are strongly affected by molecular fluctuations, i.e. ‘noise’, leading to inherent variability in indi…
View article: A locus in<i>Pristionchus pacificus</i>that is responsible for the ability to give rise to fertile offspring at higher temperatures
A locus in<i>Pristionchus pacificus</i>that is responsible for the ability to give rise to fertile offspring at higher temperatures Open
Temperature is a stress factor that varies temporally and spatially, and can affect the fitness of cold-blooded organisms, leading to a loss of reproductive output; however, little is understood about the genetics behind the long-term resp…