Simone Magnino
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View article: Alpha-synuclein pathological deposition alters functional homeostasis and connectivity of striatal dopaminergic synapses and results in microglia activation, pathology spreading, muscle stiffness, whole brain atrophy and metabolic changes before producing frank nigral neuron deafferentation
Alpha-synuclein pathological deposition alters functional homeostasis and connectivity of striatal dopaminergic synapses and results in microglia activation, pathology spreading, muscle stiffness, whole brain atrophy and metabolic changes before producing frank nigral neuron deafferentation Open
The progressive accumulation of α-synuclein (α-Syn) aggregates is believed to contribute to Parkinson’s disease (PD) pathogenesis. Nevertheless, the earliest pre-degenerative molecular, functional, neuroinflammatory and metabolic changes a…
View article: ASSESSMENT OF PCXMC MONTE CARLO SIMULATIONS IN SLOT-SCANNING-BASED EXAMINATIONS: COMPARISON WITH IN-PHANTOM THERMOLUMINESCENT DOSIMETRY
ASSESSMENT OF PCXMC MONTE CARLO SIMULATIONS IN SLOT-SCANNING-BASED EXAMINATIONS: COMPARISON WITH IN-PHANTOM THERMOLUMINESCENT DOSIMETRY Open
Slot-scanning technology is nowadays a valid solution for the follow-up of chronic musculoskeletal disorders on children and adolescent patients, but there is no commercial software designed for simulating this X-ray beam geometry. PC Prog…
View article: Detection of Chlamydial DNA from Mediterranean Loggerhead Sea Turtles in Southern Italy
Detection of Chlamydial DNA from Mediterranean Loggerhead Sea Turtles in Southern Italy Open
Chlamydiae are obligate intracellular bacteria that include pathogens of human and veterinary importance. Several reptiles were reported to host chlamydial agents, but pathogenicity in these animals still needs clarification. Given that on…
View article: Complete Genome Sequence of Chlamydia avium PV 4360/2, Isolated from a Feral Pigeon in Italy
Complete Genome Sequence of Chlamydia avium PV 4360/2, Isolated from a Feral Pigeon in Italy Open
We report here the whole-genome sequence of a Chlamydia avium isolate recovered from a feral pigeon in 1999 in Italy. Only one complete genome of a C. avium strain has been published so far. Future comparative analyses could provide valuab…
View article: Activity of synthetic peptides against <i>Chlamydia</i>
Activity of synthetic peptides against <i>Chlamydia</i> Open
The in vitro activity of six synthetic peptides against 36 strains of Chlamydia from different origins was investigated. Clavanin MO (CMO) proved to be the most active peptide, reducing the inclusion number of all Chlamydia strains from ei…
View article: Examined people and CE cases observed during the screening campaigns.
Examined people and CE cases observed during the screening campaigns. Open
View article: Distribution of CE lesions.
Distribution of CE lesions. Open
A. Number of subjects with untreated and previously treated CE cysts (bars; left Y axis) and overall prevalence of CE in the screened population (dotted line; right Y axis) according to gender and age group (X axis). M = males; F = …
View article: Human cystic echinococcosis in Morocco: Ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership
Human cystic echinococcosis in Morocco: Ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership Open
Our results show a high prevalence and on-going, likely environmental transmission of CE in the investigated provinces of Morocco, supporting the implementation of control activities in the area by national health authorities and encouragi…
View article: Evolutionary distance from the putative <i>incA</i> ancestor correlates to virulence of <i>C. pecorum</i> strains.
Evolutionary distance from the putative <i>incA</i> ancestor correlates to virulence of <i>C. pecorum</i> strains. Open
A neighbor-joining phylogram (not shown) was constructed of the conserved 5′ portion of incA of all available C. pecorum sequences, and an outgroup composed of one incA sequence of each of the 8 remaining chlamydial sp…
View article: Diversification and Distribution of Ruminant Chlamydia abortus Clones Assessed by MLST and MLVA
Diversification and Distribution of Ruminant Chlamydia abortus Clones Assessed by MLST and MLVA Open
Chlamydia abortus, an obligate intracellular bacterium, is the most common infectious cause of abortion in small ruminants worldwide and has zoonotic potential. We applied multilocus sequence typing (MLST) together with multiple-locus vari…