Simone Marrancone
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View article: Structural flexibility of the human vault protein revealed by high-resolution cryo-EM and molecular dynamics simulations
Structural flexibility of the human vault protein revealed by high-resolution cryo-EM and molecular dynamics simulations Open
Vaults are massive ribonucleoprotein complexes, highly conserved and abundant in eukaryotic cells, yet with unclear function. Their thin-walled barrel-shape architecture is composed of two symmetrical, antiparallel half-shells, each contai…