Simone Scheithauer
YOU?
Author Swipe
View article: Corrigendum to “Target attainment with continuously administered cefotaxime in critically ill patients – A retrospective cohort study”. [Journal of Critical Care (2026) Start page (t.b.a.)–End page (t.b.a.)/155264]
Corrigendum to “Target attainment with continuously administered cefotaxime in critically ill patients – A retrospective cohort study”. [Journal of Critical Care (2026) Start page (t.b.a.)–End page (t.b.a.)/155264] Open
View article: Antisepsis before skin injections: does the WHO recommendation for washing, instead alcohol-based antisepsis, achieve the same efficacy?
Antisepsis before skin injections: does the WHO recommendation for washing, instead alcohol-based antisepsis, achieve the same efficacy? Open
Introduction: Cleaning and reduction of microbial load on the skin is necessary before injections because of the colonization of the skin with resident flora and the presence of transient flora. Even after optimal skin antisepsis, there is…
View article: Target attainment with continuously administered cefotaxime in critically ill patients – a retrospective cohort study
Target attainment with continuously administered cefotaxime in critically ill patients – a retrospective cohort study Open
Our real-world analysis demonstrates that continuous administration of a standard dose of 6 g cefotaxime per day invariably ensures bactericidal plasma concentrations regarding Enterobacterales even with augmented renal function. We propos…
View article: Potential Risk Factors for Hospital-Onset Bloodstream Infections – Initial Findings Within the RISK PRINCIPE Project for Data-Driven Clinical Decision Support
Potential Risk Factors for Hospital-Onset Bloodstream Infections – Initial Findings Within the RISK PRINCIPE Project for Data-Driven Clinical Decision Support Open
Healthcare-associated infections (HAI) are a significant burden to patients, hospitals, health systems and society. Infection prevention and control measures are well established and evidence-based, however, no detailed risk assessment is …
View article: Role of vaccines in competitive displacement between SARS-CoV-2 viruses as revealed by the modeling of surveillance data
Role of vaccines in competitive displacement between SARS-CoV-2 viruses as revealed by the modeling of surveillance data Open
View article: Hygieneempfehlungen für die Regionalanästhesie
Hygieneempfehlungen für die Regionalanästhesie Open
The updated S1 guideline from the German Society of Anesthesiology and Intensive Care Medicine provides recommendations on hygiene practices for central and peripheral regional anesthesia procedures, aiming to minimize the infection risk f…
View article: Applying the theoretical framework of behavioural change to sustainable infection prevention and control based on a binational workshop
Applying the theoretical framework of behavioural change to sustainable infection prevention and control based on a binational workshop Open
While a top-down approach is essential in parts, various interventions can also be initiated and led directly by IPC practitioners. In addition, to ensure sustainable and lasting changes in practice, there needs to be structured and compre…
View article: Response: Use of integrated genomic surveillance by local public health authorities: Recommendations based on a mixed-methods study of current adoption, applications and success factors, Germany, 2023
Response: Use of integrated genomic surveillance by local public health authorities: Recommendations based on a mixed-methods study of current adoption, applications and success factors, Germany, 2023 Open
View article: An openEHR based infection control system to support monitoring of nosocomial bacterial clusters and contacts
An openEHR based infection control system to support monitoring of nosocomial bacterial clusters and contacts Open
Early outbreak detection, allowing rapid intervention, is essential to reduce the burden of healthcare-associated pathogen transmission, including multidrug-resistant bacteria. Digital, routine data-driven solutions are promising, but ofte…
View article: Responsive population-based cohorts as platforms for characterising pathogen- and population-level infection dynamics for epidemic prevention, preparedness and response
Responsive population-based cohorts as platforms for characterising pathogen- and population-level infection dynamics for epidemic prevention, preparedness and response Open
Establishing population-based cohorts is indispensable for effective epidemic prevention, preparedness and response. Existing passive surveillance systems face limitations in their capacity to promptly provide representative data for estim…
View article: S2k Guideline: Hygienic requirements for patient beds, bed linen, bed accessories and personal protection when handling beds
S2k Guideline: Hygienic requirements for patient beds, bed linen, bed accessories and personal protection when handling beds Open
Hospitalized patients are often more susceptible to infection than healthy people due to their illness, the presence of devices and their reduced immune defenses. At the same time, potentially pathogenic pathogens, which are often characte…
View article: Use of integrated genomic surveillance by local public health authorities: Recommendations based on a mixed-methods study of current adoption, applications and success factors, Germany, 2023
Use of integrated genomic surveillance by local public health authorities: Recommendations based on a mixed-methods study of current adoption, applications and success factors, Germany, 2023 Open
Background Integrated genomic surveillance (IGS), i.e. the integrated analysis of pathogen whole genome sequencing and classical epidemiological data, can contribute substantially to the disease surveillance and infection prevention activi…
View article: Psychische Gesundheit und psychiatrisch-psychotherapeutische Versorgung als Elemente von „pandemic and crisis preparedness“
Psychische Gesundheit und psychiatrisch-psychotherapeutische Versorgung als Elemente von „pandemic and crisis preparedness“ Open
Zusammenfassung Hintergrund Die COVID-19(„coronavirus disease 2019“)-Pandemie war herausfordernd bezüglich der psychischen Gesundheit der Bevölkerung und der psychiatrisch-psychotherapeutischen Versorgung. Ziele der Arbeit Erkenntnisse aus…
View article: S1-Leitlinie Nachhaltigkeit in der Intensiv- und Notfallmedizin
S1-Leitlinie Nachhaltigkeit in der Intensiv- und Notfallmedizin Open
View article: More than rewards: insights into a hospital infection prevention and control gamification strategy
More than rewards: insights into a hospital infection prevention and control gamification strategy Open
The intervention effectively engaged medical and non-medical staff in IPC topics, positively influencing HCW work flow and increasing ABHS consumption. These findings highlight gamification as a promising approach for IPC education.
View article: Empowering Communities: Tailored Pandemic Data Visualization for Varied Tasks and Users
Empowering Communities: Tailored Pandemic Data Visualization for Varied Tasks and Users Open
Data visualization methodologies were intensively leveraged during the COVID-19 pandemic. We review our design experience working on a set of interdisciplinary COVID-19 pandemic projects. We describe the challenges we met in these projects…
View article: Priorisierung von Forschungsfragen in Gesundheitskrisen – Vorstellung eines Konzeptes, entwickelt in der COVID-19 Pandemie
Priorisierung von Forschungsfragen in Gesundheitskrisen – Vorstellung eines Konzeptes, entwickelt in der COVID-19 Pandemie Open
View article: Zusammenfassung der S1-Leitlinie Nachhaltigkeit in der Intensiv- und Notfallmedizin
Zusammenfassung der S1-Leitlinie Nachhaltigkeit in der Intensiv- und Notfallmedizin Open
The guideline shows that there are already relevant and concrete possibilities for more sustainable work in intensive care and emergency medicine. However, there is a need for further research (e.g., detailed analyses, such as life cycle a…
View article: Feasibility of hand disinfection in paediatric advanced life support (PALS): A simulation study
Feasibility of hand disinfection in paediatric advanced life support (PALS): A simulation study Open
The categorical omission of hand disinfection in PALS seems to be no longer acceptable or appropriate. The feasibility of hand hygiene should be re-evaluated in real-world scenarios.
View article: Six clinical phenotypes with prognostic implications were identified by unsupervised machine learning in children and adolescents with SARS-CoV-2 infection: results from a German nationwide registry
Six clinical phenotypes with prognostic implications were identified by unsupervised machine learning in children and adolescents with SARS-CoV-2 infection: results from a German nationwide registry Open
Objective Phenotypes are important for patient classification, disease prognostication, and treatment customization. We aimed to identify distinct clinical phenotypes of children and adolescents hospitalized with SARS-CoV-2 infection, and …
View article: Uncovering Prognostic Clinical Phenotypes in Children and Adolescents with SARS-CoV-2 Infection
Uncovering Prognostic Clinical Phenotypes in Children and Adolescents with SARS-CoV-2 Infection Open
Background Characterizing clinical phenotypes is important for classifying patients, predicting disease outcomes, and adapting treatment. We aimed to identify distinct clinical phenotypes among hospitalized children and adolescents with SA…
View article: A retrospective cohort analysis of factors influencing continuous antibiotic therapy with ampicillin
A retrospective cohort analysis of factors influencing continuous antibiotic therapy with ampicillin Open
View article: Non-pharmaceutical infection prevention measures in nosocomial SARS-CoV-2 outbreaks: a retrospective multi-centre cohort study
Non-pharmaceutical infection prevention measures in nosocomial SARS-CoV-2 outbreaks: a retrospective multi-centre cohort study Open
Our data provide insights in non-pharmaceutical outbreak prevention and management, revealing that the mandatory use of face masks by patients in the presence of HCWs and a high patient screening frequency in ongoing outbreaks were signifi…
View article: How long do bacteria, fungi, protozoa, and viruses retain their replication capacity on inanimate surfaces? A systematic review examining environmental resilience versus healthcare-associated infection risk by “fomite-borne risk assessment”
How long do bacteria, fungi, protozoa, and viruses retain their replication capacity on inanimate surfaces? A systematic review examining environmental resilience versus healthcare-associated infection risk by “fomite-borne risk assessment” Open
SUMMARY In healthcare settings, contaminated surfaces play an important role in the transmission of nosocomial pathogens potentially resulting in healthcare-associated infections (HAI). Pathogens can be transmitted directly from frequent h…
View article: The use of single-use medical gloves in doctors’ practices and hospitals
The use of single-use medical gloves in doctors’ practices and hospitals Open
Limiting the use of single-use medical gloves to its proper indications promotes the safety of health-care professionals and patients and has beneficial ecological and economic effects as well.
View article: Infection prevention and control in 2030: a first qualitative survey by the Crystal Ball Initiative
Infection prevention and control in 2030: a first qualitative survey by the Crystal Ball Initiative Open
Background Healthcare delivery is undergoing radical changes that influence effective infection prevention and control (IPC). Futures research (short: Futures), the science of deliberating on multiple potential future states, is increasing…
View article: Pandemic Preparedness – Ein Vorschlag für eine Forschungsinfrastruktur und ihre Funktionalitäten für ein resilientes Gesundheitsforschungssystem
Pandemic Preparedness – Ein Vorschlag für eine Forschungsinfrastruktur und ihre Funktionalitäten für ein resilientes Gesundheitsforschungssystem Open
Zusammenfassung Während einer Pandemie muss Resilienz nicht nur als Eigenschaft des Gesundheitssystems, sondern auch des umgebenden Forschungsumfelds betrachtet werden. Um verlässliche, evidenzbasierte Empfehlungen aus der Universitätsmedi…
View article: Innovative teaching in infection prevention and control and infectious diseases education: testing and investigation of student perceptions
Innovative teaching in infection prevention and control and infectious diseases education: testing and investigation of student perceptions Open
Purpose Many curricula promote frontal teaching approaches, potentially decreasing interaction and motivation – also within infection prevention & control and infectious diseases (IPC/ID). We aimed to investigate the implementation of thre…
View article: Architectural interventions to mitigate the spread of SARS-CoV-2 in emergency departments
Architectural interventions to mitigate the spread of SARS-CoV-2 in emergency departments Open
These modelling results highlight the importance of IPC architectural interventions; they can be devised independently of profound knowledge of an emerging pathogen, focusing on technical, constructive, and functional components. These res…
View article: Evaluation of the practice of reprocessing ORs in German hospitals from an infection prevention and control perspective
Evaluation of the practice of reprocessing ORs in German hospitals from an infection prevention and control perspective Open
Background The aim of this study was to analyze the cleaning and disinfection of operating rooms (ORs) status quo focusing on hygiene plans in German hospitals. Methods In 2016, a structured online survey was sent to infection prevention a…