Simone Scherrer
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View article: Stereotypic immune response in <i>Mycobacterium avium</i> ssp. <i>paratuberculosis</i> infection among different Swiss caprine genotypes
Stereotypic immune response in <i>Mycobacterium avium</i> ssp. <i>paratuberculosis</i> infection among different Swiss caprine genotypes Open
Paratuberculosis is an infection with Mycobacterium avium ssp. paratuberculosis (MAP) causing chronic enteritis in domestic and wild ruminants worldwide. In goats, the infection is caused by C (cattle)-type and S (sheep)-type strains. In t…
View article: Genetic diversity and antimicrobial susceptibility of Streptococcus suis from diseased Swiss pigs collected between 2019 – 2022
Genetic diversity and antimicrobial susceptibility of Streptococcus suis from diseased Swiss pigs collected between 2019 – 2022 Open
Streptococcus suis is an important pathogen causing severe disease in pigs and humans, giving rise to economic losses in the pig production industry. Out of 65 S. suis isolates collected from diseased pigs in Switzerland between 2019 and 2…
View article: Isolation of Mycobacterium avium ssp. paratuberculosis and other non-tuberculous mycobacteria from head lymph nodes of wild ruminants and badgers in Switzerland
Isolation of Mycobacterium avium ssp. paratuberculosis and other non-tuberculous mycobacteria from head lymph nodes of wild ruminants and badgers in Switzerland Open
Introduction The family Mycobacteriaceae contains over 188 species, most of which are saprophytic non-tuberculous mycobacteria (NTM). In wildlife, a variety of different NTM can be found, with different reports about their pathogenic poten…
View article: Development of a new multiplex quantitative PCR for the detection of <i>Glaesserella parasuis</i>, <i>Mycoplasma hyorhinis</i>, and <i>Mycoplasma hyosynoviae</i>
Development of a new multiplex quantitative PCR for the detection of <i>Glaesserella parasuis</i>, <i>Mycoplasma hyorhinis</i>, and <i>Mycoplasma hyosynoviae</i> Open
Glaesserella parasuis , Mycoplasma hyorhinis , and Mycoplasma hyosynoviae are important porcine pathogens responsible for polyserositis, polyarthritis, meningitis, pneumonia, and septicemia causing significant economic losses in the swine …
View article: Strain diversity in Mycobacterium avium subsp. paratuberculosis-positive bovine fecal samples collected in Switzerland
Strain diversity in Mycobacterium avium subsp. paratuberculosis-positive bovine fecal samples collected in Switzerland Open
Paratuberculosis or Johne’s disease is a chronic intestinal disease in domestic and wild ruminants. It affects global dairy economy and is caused by Mycobacterium avium subsp. paratuberculosis (MAP). The objective of this study was to anal…
View article: Identification of Glaesserella parasuis and Differentiation of Its 15 Serovars Using High-Resolution Melting Assays
Identification of Glaesserella parasuis and Differentiation of Its 15 Serovars Using High-Resolution Melting Assays Open
Glaesserella parasuis is the etiological agent of Glässer’s disease, which is associated with polyserositis and arthritis and has a significant impact on the economy of the pig production industry. For the optimal surveillance of this path…
View article: Development of a novel high resolution melting assay for identification and differentiation of all known 19 serovars of Actinobacillus pleuropneumoniae
Development of a novel high resolution melting assay for identification and differentiation of all known 19 serovars of Actinobacillus pleuropneumoniae Open
Actinobacillus (A.) pleuropneumoniae is the etiological agent of porcine pleuropneumonia, a respiratory infectious disease responsible for global economic losses in the pig industry. From a monitoring perspective…
View article: Development of a novel high resolution melting assay for identification and differentiation of all known 19 serovars of <i>Actinobacillus pleuropneumoniae</i>
Development of a novel high resolution melting assay for identification and differentiation of all known 19 serovars of <i>Actinobacillus pleuropneumoniae</i> Open
Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, a respiratory infectious disease responsible for global economic losses in the pig industry. From a monitoring perspective as well as due to the different…
View article: Development of a novel high resolution melting assay for identification and differentiation of all known 19 serovars of Actinobacillus pleuropneumoniae
Development of a novel high resolution melting assay for identification and differentiation of all known 19 serovars of Actinobacillus pleuropneumoniae Open
Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, a respiratory infectious disease responsible for global economic losses in the pig industry. From a monitoring perspective as well as due to the different…
View article: Draft Genome Sequences of Two Clinical Actinobacillus pleuropneumoniae Serotype 19 Strains from Pigs in Switzerland
Draft Genome Sequences of Two Clinical Actinobacillus pleuropneumoniae Serotype 19 Strains from Pigs in Switzerland Open
Actinobacillus pleuropneumoniae serotype 19 is a very recently described new serotype with a novel type II capsule locus. Here, we report the draft genome sequences of two Actinobacillus pleuropneumoniae serotype 19 strains with a serogrou…
View article: Novel multiplex TaqMan assay for differentiation of the four major pathogenic <i>Brachyspira</i> species in swine
Novel multiplex TaqMan assay for differentiation of the four major pathogenic <i>Brachyspira</i> species in swine Open
A novel TaqMan 5‐plex real‐time PCR using a combination of locked nucleic acid‐modified (LNA)‐ and minor groove binding (MGB)‐conjugated DNA probes was developed for identification and differentiation between the four main pathogenic Brach…
View article: Novel multiplex TaqMan assay for differentiation of the four major pathogenic Brachyspira species in swine
Novel multiplex TaqMan assay for differentiation of the four major pathogenic Brachyspira species in swine Open
Table S1 503 Brachyspira samples used for validation of the novel 5-plex qPCR assay and comparison of results obtained by four independent PCR assays
View article: Novel multiplex TaqMan assay for differentiation of the four major pathogenic Brachyspira species in swine
Novel multiplex TaqMan assay for differentiation of the four major pathogenic Brachyspira species in swine Open
Table S1 503 Brachyspira samples used for validation of the novel 5-plex qPCR assay and comparison of results obtained by four independent PCR assays
View article: Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland
Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland Open
View article: Rapid high resolution melting assay to differentiate <i>Streptococcus suis</i> serotypes 2, 1/2, 1, and 14
Rapid high resolution melting assay to differentiate <i>Streptococcus suis</i> serotypes 2, 1/2, 1, and 14 Open
This rapid high resolution melting (HRM) assay allows distinguishing between Streptococcus suis serotype pairs 2 and 1/2 as well as 1 and 14, respectively, based on a single‐nucleotide polymorphism within capsular polysaccharide synthesis …
View article: Additional file 2 of Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland
Additional file 2 of Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland Open
Additional file 2. Clinical data, genotyping, and determination of virulence markers of Swiss porcineS. suisisolates (n = 88).
View article: Additional file 3 of Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland
Additional file 3 of Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland Open
Additional file 3. Distribution of porcineS. suisisolates in relation to sequence type and clonal complex.
View article: Additional file 1 of Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland
Additional file 1 of Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland Open
Additional file 1. Capsular type distribution among SwissS. suisisolates. Number of isolates in relation to capsular type is indicated. NT = nontypeable due to no successful capsular typing by multiplex PCR.
View article: Three‐reaction high‐resolution melting assay for rapid differentiation of <i>Mycobacterium tuberculosis</i> complex members
Three‐reaction high‐resolution melting assay for rapid differentiation of <i>Mycobacterium tuberculosis</i> complex members Open
The possibility of introducing a reliable assay for a quick identification and differentiation of the main species of Mycobacterium tuberculosis complex (MTBC) supports the improvement of efficient tuberculosis combating strategies worldwi…
View article: Morphological and Molecular Characterization of a New Mycobacterium avium Subsp. paratuberculosis S-Type Strain Genotype in Goats
Morphological and Molecular Characterization of a New Mycobacterium avium Subsp. paratuberculosis S-Type Strain Genotype in Goats Open
Paratuberculosis is a chronic bacterial disease of global importance mainly in domestic and wild ruminants, caused by Mycobacterium avium subsp. paratuberculosis (MAP). In goats, paratuberculosis is mostly caused by the "C-ty…
View article: Development of a new High Resolution Melting (HRM) assay for identification and differentiation of Mycobacterium tuberculosis complex samples
Development of a new High Resolution Melting (HRM) assay for identification and differentiation of Mycobacterium tuberculosis complex samples Open
View article: Distribution and expression of <i>esat-6</i> and <i>cfp-10</i> in non-tuberculous mycobacteria isolated from lymph nodes of slaughtered cattle in Switzerland
Distribution and expression of <i>esat-6</i> and <i>cfp-10</i> in non-tuberculous mycobacteria isolated from lymph nodes of slaughtered cattle in Switzerland Open
The most commonly used tools for tuberculosis testing in cattle, the tuberculin skin test and the interferon-γ release assay, detect immune reactivity to various antigens of Mycobacterium bovis, including ESAT-6 and CFP-10. However, some n…
View article: Molecular Characterization of Mycobacterium avium subsp. hominissuis of Two Groups of Lymph Nodes, Being Intradermal Tuberculin or Interferon-Gamma Test Positive and Negative, Isolated from Swiss Cattle at Slaughter
Molecular Characterization of Mycobacterium avium subsp. hominissuis of Two Groups of Lymph Nodes, Being Intradermal Tuberculin or Interferon-Gamma Test Positive and Negative, Isolated from Swiss Cattle at Slaughter Open
Mycobacterium avium subsp. hominissuis (MAH) is an important zoonotic pathogen with raising global health concerns. In humans, MAH is one of the most widespread non-tuberculous mycobacterial species responsible for lung disea…
View article: Non-tuberculous<i>Mycobacteria</i>isolated from lymph nodes and faecal samples of healthy slaughtered cattle and the abattoir environment
Non-tuberculous<i>Mycobacteria</i>isolated from lymph nodes and faecal samples of healthy slaughtered cattle and the abattoir environment Open
Infections caused by non-tuberculous mycobacteria (NTM) are reported as emerging disease in many countries worldwide. The occurrence of NTM in different hosts and their implication as obligate or opportunistic pathogen remain largely uncle…
View article: Epidemiological tracing of bovine tuberculosis in Switzerland, multilocus variable number of tandem repeat analysis of Mycobacterium bovis and Mycobacterium caprae
Epidemiological tracing of bovine tuberculosis in Switzerland, multilocus variable number of tandem repeat analysis of Mycobacterium bovis and Mycobacterium caprae Open
The present study is the first MIRU-VNTR analysis of Swiss bTB mycobacterial isolates. The genotyping assay was found to be highly discriminating and suitable for the epidemiological tracing of further outbreaks. These findings will contri…
View article: A novel quantitative real-time polymerase chain reaction method for detecting toxigenic Pasteurella multocida in nasal swabs from swine
A novel quantitative real-time polymerase chain reaction method for detecting toxigenic Pasteurella multocida in nasal swabs from swine Open
View article: A novel multiplex qPCR targeting 23S rDNA for diagnosis of swine dysentery and porcine intestinal spirochaetosis
A novel multiplex qPCR targeting 23S rDNA for diagnosis of swine dysentery and porcine intestinal spirochaetosis Open