Subash C. Gupta
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View article: Sol–Gel Synthesized Co‐Doped Ilmenite‐NiTiO<sub>3</sub> for Oxygen Evolution Reaction: Interplay of Inductive Effect and Crystal Structure
Sol–Gel Synthesized Co‐Doped Ilmenite‐NiTiO<sub>3</sub> for Oxygen Evolution Reaction: Interplay of Inductive Effect and Crystal Structure Open
The oxygen evolution reaction is key to advancing hydrogen production, energy storage, and sustainable energy technologies. In this study, we have explored the ilmenite‐type Co‐substituted NiTiO 3 as a promising OER catalyst in the alkalin…
View article: Mercapto-NSAIDs generate a non-steroidal anti-inflammatory drug (NSAID) and hydrogen sulfide
Mercapto-NSAIDs generate a non-steroidal anti-inflammatory drug (NSAID) and hydrogen sulfide Open
A new class of mercapto-NSAIDs that generate persulfide, H 2 S, and the NSAID is reported.
View article: Supplementary Figure 1 from Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment
Supplementary Figure 1 from Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment Open
PDF file - 130K, Nimbolide is bioavailable in the plasma and colorectal tumor tissues of nude mice. A, HPLC chromatogram of pure nimbolide. B, HPLC chromatogram of nimbolide in plasma. C, HPLC chromatogram of nimbolide in tumor tissues.
View article: Data from Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment
Data from Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment Open
Purpose: Extensive research over the past decade has revealed that the proinflammatory microenvironment plays a critical role in the development of colorectal cancer. Whether nimbolide, a limonoid triterpene, can inhibit the growth of colo…
View article: Data from Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment
Data from Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment Open
Purpose: Extensive research over the past decade has revealed that the proinflammatory microenvironment plays a critical role in the development of colorectal cancer. Whether nimbolide, a limonoid triterpene, can inhibit the growth of colo…
View article: Supplementary Figure 1 from Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment
Supplementary Figure 1 from Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment Open
PDF file - 130K, Nimbolide is bioavailable in the plasma and colorectal tumor tissues of nude mice. A, HPLC chromatogram of pure nimbolide. B, HPLC chromatogram of nimbolide in plasma. C, HPLC chromatogram of nimbolide in tumor tissues.
View article: CCDC 2239933: Experimental Crystal Structure Determination
CCDC 2239933: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Editorial: Targeting triple negative breast cancer by natural compounds
Editorial: Targeting triple negative breast cancer by natural compounds Open
EDITORIAL article Front. Pharmacol., 17 March 2023Sec. Pharmacology of Anti-Cancer Drugs Volume 14 - 2023 | https://doi.org/10.3389/fphar.2023.1172245
View article: 526 miR-15a and miR-15b modulate natural killer and CD8<sup>+</sup>T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma
526 miR-15a and miR-15b modulate natural killer and CD8<sup>+</sup>T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma Open
Background Neuroblastoma (NB) is an enigmatic and deadliest pediatric cancer to treat. The major obstacles to effective immuno- therapy treatments in NB are defective immune cells and the immune evasion tactics deployed by the tumor cells …
View article: Synthesis, Characterizations, Crystal structure, DFTand Hirshfeld surface analysis of4-cyclohexyl-1-(thiophene-2-carbonyl)thiosemicarbazide
Synthesis, Characterizations, Crystal structure, DFTand Hirshfeld surface analysis of4-cyclohexyl-1-(thiophene-2-carbonyl)thiosemicarbazide Open
The crystal structure of the thiosemicarbazide derivative 4-cyclohexyl-1-(thiophene-2-carbonyl)thiosemicarbazide (ChtcTSC), C 12 H 17 N 3 OS 2 , is reported here. The title compound ChtcTSC has been characterized by various physicochemical…
View article: Combination Therapy Comprising Paclitaxel and 5-Fluorouracil by Using Folic Acid Functionalized Bovine Milk Exosomes Improves the Therapeutic Efficacy against Breast Cancer
Combination Therapy Comprising Paclitaxel and 5-Fluorouracil by Using Folic Acid Functionalized Bovine Milk Exosomes Improves the Therapeutic Efficacy against Breast Cancer Open
Paclitaxel (PAC) has been approved by FDA for clinical use (Taxol®), yet dose-dependent severe toxicity due to the adjuvant Cremophor EL® in combination with ethanol is a major drawback. The drawbacks of the current therapy can be overcome…
View article: Transcription factor 4 expression and correlation with tumor progression in gallbladder cancer
Transcription factor 4 expression and correlation with tumor progression in gallbladder cancer Open
Background: Dysregulation in Wnt/β-catenin signaling has been associated with the initiation and metastasis of cancer cells. Transcription factor 4 (TCF4) (also named as transcription factor 7-like 2) is a key transcriptional factor of the…
View article: Semecarpus Anacardium Linn. Leaf Extract Exhibits Activities Against Breast Cancer And Prolongs The Survival of Tumor Bearing Mice
Semecarpus Anacardium Linn. Leaf Extract Exhibits Activities Against Breast Cancer And Prolongs The Survival of Tumor Bearing Mice Open
Semecarpus anacardium Linn. is a commonly used Ayurvedic medicinal plant which nuts have been described in Ayurveda and Sidda system of medicine to treat clinical ailments such as vitiligo, inflamation, microbial infection, geriatric probl…
View article: Is Upregulation of Sarcolipin Beneficial or Detrimental to Muscle Function?
Is Upregulation of Sarcolipin Beneficial or Detrimental to Muscle Function? Open
Sarcolipin (SLN) is a regulator of sarco/endo plasmic reticulum Ca 2+ -ATPase (SERCA) pump and has been shown to be involved in muscle nonshivering thermogenesis (NST) and energy metabolism. Interestingly, SLN expression is significantly u…
View article: COVID-19 AND CANCER COMORBIDITY: THERAPEUTIC OPPORTUNITIES AND CHALLENGES (RUSSIAN TRANSLATION)
COVID-19 AND CANCER COMORBIDITY: THERAPEUTIC OPPORTUNITIES AND CHALLENGES (RUSSIAN TRANSLATION) Open
The coronavirus disease 2019 (COVID-19) is a viral disease caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that affects the respiratory system of infected individuals. COVID-19 spreads between humans through …
View article: Epoxyazadiradione exhibit activities in head and neck squamous cell carcinoma by targeting multiple pathways
Epoxyazadiradione exhibit activities in head and neck squamous cell carcinoma by targeting multiple pathways Open
The head and neck squamous cell carcinoma (HNSCC) constitute about 90% of all head and neck cancers. HNSCC falls in the top 10 cancers in men globally. Epoxyazadiradione (EPA) and Azadiradione (AZA) are the limonoids derived from the medic…
View article: <i>Semecarpus anacardium</i>Linn. leaf extract exhibits activities against breast cancer and prolongs the survival of tumor-bearing mice
<i>Semecarpus anacardium</i>Linn. leaf extract exhibits activities against breast cancer and prolongs the survival of tumor-bearing mice Open
Semecarpus anacardium Linn. is commonly used in various traditional medicines from ancient times. The nuts have been described in Ayurveda medication systems to treat numerous clinical ailments. However, isolating phytochemical constituent…