Shuping Tan
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View article: A history of suicide attempts among individuals with schizophrenia is associated with tryptophan degradation via the salivary kynurenine pathway
A history of suicide attempts among individuals with schizophrenia is associated with tryptophan degradation via the salivary kynurenine pathway Open
The findings suggest that a history of suicide attempts is associated with alterations in salivary tryptophan concentration and the metabolic shift from tryptophan to kynurenine. These results contribute to the understanding of the potenti…
View article: Cross-sectional and longitudinal network analyses depict variations of symptom networks in depression patients across the lifespan: insight from a large-scale sample
Cross-sectional and longitudinal network analyses depict variations of symptom networks in depression patients across the lifespan: insight from a large-scale sample Open
This study emphasises the dynamic and developmentally specific structuring of depressive symptom networks across the lifespan. Distinct central symptoms and varying levels of symptom connectivity across age groups suggest stage-specific ps…
View article: Emergency Sound Recognition and Direction Indication Using Machine Learning for Individuals with Hearing Loss
Emergency Sound Recognition and Direction Indication Using Machine Learning for Individuals with Hearing Loss Open
Sound is a vital means of expression and communication. However, individuals with hearing loss face considerable challenges, particularly in emergency situations. During such events, alerts and critical information are typically conveyed t…
View article: Mental Stress and Relaxation Conditions of Engineering Students based on EEG Brainwave Signals using Machine Learning: A Case Study
Mental Stress and Relaxation Conditions of Engineering Students based on EEG Brainwave Signals using Machine Learning: A Case Study Open
The rising prevalence of mental health challenges among engineering students highlights the necessity for improved methods in recognising and managing stress. Conventional self-evaluation techniques seem to be subject to interpretation whe…
View article: The role of difficulties in emotion regulation on non-suicidal self-injury and suicide attempts: a cross-sectional study of Chinese adolescents
The role of difficulties in emotion regulation on non-suicidal self-injury and suicide attempts: a cross-sectional study of Chinese adolescents Open
Non-suicidal self-injury (NSSI) and suicide attempts (SA) among adolescents are issues of widespread concern. Non-suicidal self-injury and attempted suicide are both risk factors for suicide, and difficulties in emotion regulation (DER) ma…
View article: Positive school climate boosts children’s reading achievement, mental health and cortical thinning
Positive school climate boosts children’s reading achievement, mental health and cortical thinning Open
Growing evidence underscores school climate as an important protective factor for children's academic achievement and mental health. However, whether and how school climate impacts child development from behavioral to brain has remained la…
View article: Analysis and Prediction of Schizophrenia Patients Based on High-Order Graph Attention Generative Adversarial Networks
Analysis and Prediction of Schizophrenia Patients Based on High-Order Graph Attention Generative Adversarial Networks Open
Generative Adversarial Networks, a popular deep learning method, have achieved excellent performance in both classification and prediction tasks. However, there have been relatively few applications of generative adversarial networks to EE…
View article: Investigation of Electroencephalographic (EEG) Brainwave Signal on Mental Stress through Psychomotor Activities
Investigation of Electroencephalographic (EEG) Brainwave Signal on Mental Stress through Psychomotor Activities Open
Mental well-being plays a crucial aspect in human life alongside physical health. A positive mental health allows individuals to engage in healthy relationship, navigate challenges in a positive manner and enjoys a sense of fulfilment upon…
View article: Physical activity alleviates mental health problems related to bullying through moderating rumination
Physical activity alleviates mental health problems related to bullying through moderating rumination Open
Rumination and physical activity mediated and moderated, respectively, the relationship between experiencing bullying and adolescents' mental health problems. These findings indicate that schools and society should establish a campus bully…
View article: Schizophrenia recognition based on three-dimensional adaptive graph convolutional neural network
Schizophrenia recognition based on three-dimensional adaptive graph convolutional neural network Open
Previous deep learning-based brain network research has made significant progress in understanding the pathophysiology of schizophrenia. However, it ignores the three-dimensional spatial characteristics of EEG signals and cannot dynamicall…
View article: Depression Recognition Using Daily Wearable-Derived Physiological Data
Depression Recognition Using Daily Wearable-Derived Physiological Data Open
The objective identification of depression using physiological data has emerged as a significant research focus within the field of psychiatry. The advancement of wearable physiological measurement devices has opened new avenues for the id…
View article: Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents
Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents Open
ChiCTR2100044553, Registered March 24, 2021.
View article: Multicentre analysis of seizure outcome predicted by removal of high-frequency oscillations
Multicentre analysis of seizure outcome predicted by removal of high-frequency oscillations Open
In drug-resistant focal epilepsy, planning surgical resection can involve presurgical intracranial EEG (iEEG) recordings to detect seizures and other iEEG patterns to improve postsurgical seizure outcome. We hypothesized that resection of …
View article: High-order brain network feature extraction and classification method of first-episode schizophrenia: an EEG study
High-order brain network feature extraction and classification method of first-episode schizophrenia: an EEG study Open
Introduction A multimodal persistent topological feature extraction and classification method is proposed to enhance the recognition accuracy of first-episode schizophrenia patients. This approach addresses the limitations of traditional h…
View article: Segregation of the regional radiomics similarity network exhibited an increase from late childhood to early adolescence: A developmental investigation
Segregation of the regional radiomics similarity network exhibited an increase from late childhood to early adolescence: A developmental investigation Open
Brain development is characterized by an increase in structural and functional segregation, which supports the specialization of cognitive processes within the context of network neuroscience. In this study, we investigated age-related cha…
View article: <i>N</i>-Methyl-<scp>d</scp>-Aspartate Receptor Antibody and Sensory Gating Deficits in Non-smoking, Minimal Antipsychotic Medication Exposure, and First-Episode Patients With Schizophrenia
<i>N</i>-Methyl-<span>d</span>-Aspartate Receptor Antibody and Sensory Gating Deficits in Non-smoking, Minimal Antipsychotic Medication Exposure, and First-Episode Patients With Schizophrenia Open
Background and Hypothesis Sensory gating deficit is considered a pathophysiological feature of schizophrenia, which has been linked to N-methyl-d-aspartate receptor (NMDAR) hypofunction as one of the potential underlying mechanisms. Here, …
View article: Microstate D as a Biomarker in Schizophrenia: Insights from Brain State Transitions
Microstate D as a Biomarker in Schizophrenia: Insights from Brain State Transitions Open
Objectives. There is a significant correlation between EEG microstate and the neurophysiological basis of mental illness, brain state, and cognitive function. Given that the unclear relationship between network dynamics and different micro…
View article: Research of 3D-AGCN Schizophrenia Classification Model
Research of 3D-AGCN Schizophrenia Classification Model Open
Previous deep learning-based brain network research has made significant progress in understanding the pathophysiology of schizophrenia. However, it ignores the three-dimensional spatial characteristics of EEG signals and cannot dynamicall…
View article: A spectrum of altered non-rapid eye movement sleep in schizophrenia
A spectrum of altered non-rapid eye movement sleep in schizophrenia Open
Multiple facets of sleep neurophysiology, including electroencephalography (EEG) metrics such as non-rapid eye movement (NREM) spindles and slow oscillations, are altered in individuals with schizophrenia (SCZ). However, beyond group-level…
View article: Is game-based therapy effective for treating cognitive deficits in adults with schizophrenia? Evidence from a randomized controlled trial
Is game-based therapy effective for treating cognitive deficits in adults with schizophrenia? Evidence from a randomized controlled trial Open
Cognitive deficits in schizophrenia are a major contributor to poor functional outcomes and everyday functioning, making them a promising therapeutic target. Recent years have witnessed a dramatic increase in the use of digital interventio…
View article: The continuous differentiation of multiscale structural gradients from childhood to adolescence correlates with the maturation of cortical morphology and functional specialization
The continuous differentiation of multiscale structural gradients from childhood to adolescence correlates with the maturation of cortical morphology and functional specialization Open
From childhood to adolescence, the structural organization of the human brain undergoes dynamic and regionally heterogeneous changes across multiple scales, from synaptic pruning to the reorganization of large-scale anatomical wiring. Howe…
View article: History of suicidal behavior and clozapine prescribing among people with schizophrenia in China: a cohort study
History of suicidal behavior and clozapine prescribing among people with schizophrenia in China: a cohort study Open
Background Clozapine is an off-label drug used in most countries to prevent suicide in individuals with schizophrenia. However, few studies have reported real-world prescription practices. This study aimed to explore the association betwee…
View article: Development of the triadic neural systems involved in risky decision-making during childhood
Development of the triadic neural systems involved in risky decision-making during childhood Open
Risk-taking often occurs in childhood as a compex outcome influenced by individual, family, and social factors. The ability to govern risky decision-making in a balanced manner is a hallmark of the integrity of cognitive and affective deve…