Sindhuri Prakash
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View article: Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy
Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy Open
Aberrant O-glycosylation of the IgA1 hinge region is a characteristic finding in patients with IgA nephropathy (IgAN) and is thought to contribute to immune-complex formation and kidney injury. Other studies have suggested that abnormaliti…
View article: Type IV Collagen Mutations in Familial IgA Nephropathy
Type IV Collagen Mutations in Familial IgA Nephropathy Open
View article: GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway
GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway Open
Aberrant O-glycosylation of serum immunoglobulin A1 (IgA1) represents a heritable pathogenic defect in IgA nephropathy, the most common form of glomerulonephritis worldwide, but specific genetic factors involved in its determination are no…
View article: GWAS for serum galactose-deficient IgA1 implicates critical genes of the<i>O</i>-glycosylation pathway
GWAS for serum galactose-deficient IgA1 implicates critical genes of the<i>O</i>-glycosylation pathway Open
Aberrant O -glycosylation of serum immunoglobulin A1 (IgA1) represents a heritable pathogenic defect in IgA nephropathy, the most common form of glomerulonephritis worldwide, but specific genetic factors involved in its determination are n…