Sindy Kueh
YOU?
Author Swipe
View article: Six weeks of N-acetylcysteine antioxidant in drinking water decreases pathological fiber branching in MDX mouse dystrophic fast-twitch skeletal muscle
Six weeks of N-acetylcysteine antioxidant in drinking water decreases pathological fiber branching in MDX mouse dystrophic fast-twitch skeletal muscle Open
Introduction: It has been proposed that an increased susceptivity to oxidative stress caused by the absence of the protein dystrophin from the inner surface of the sarcolemma is a trigger of skeletal muscle necrosis in the destructive dyst…
View article: Chan_et_al_2022_Data.xlsx
Chan_et_al_2022_Data.xlsx Open
Underlying data for Figures 2D, 3C, 3D, 4D and 5D of the paper "Sarcoplasmic reticulum calcium handling in unbranched, immediately post-necrotic fast-twitch mdx fibres is similar to wild-type littermates" by Chan et al. (2022).
View article: Lifespan Analysis of Dystrophic mdx Fast-Twitch Muscle Morphology and Its Impact on Contractile Function
Lifespan Analysis of Dystrophic mdx Fast-Twitch Muscle Morphology and Its Impact on Contractile Function Open
Duchenne muscular dystrophy is caused by the absence of the protein dystrophin from skeletal muscle and is characterized by progressive cycles of necrosis/regeneration. Using the dystrophin deficient mdx mouse model, we studied the morphol…
View article: SR Ca<sup>2+</sup> handling in unbranched, immediately post-necrotic fast-twitch <i>mdx</i> fibres is similar to <i>wt</i> littermates
SR Ca<sup>2+</sup> handling in unbranched, immediately post-necrotic fast-twitch <i>mdx</i> fibres is similar to <i>wt</i> littermates Open
There is a lack of consensus in the literature regarding the effects of dystrophin deficiency on the Ca 2+ -handling properties of the SR in mdx mice, an animal model of Duchenne muscular dystrophy. One possible reason for this is that onl…
View article: Lifespan analysis of dystrophic <i>mdx</i> fast-twitch muscle morphology and its impact on contractile function
Lifespan analysis of dystrophic <i>mdx</i> fast-twitch muscle morphology and its impact on contractile function Open
Duchenne muscular dystrophy is caused by the absence of the protein dystrophin from skeletal muscle and is characterized by progressive cycles of necrosis/regeneration. Using the dystrophin deficient mdx mouse model we studied the morpholo…
View article: Branched fibers from old fast-twitch dystrophic muscles are the sites of terminal damage in muscular dystrophy
Branched fibers from old fast-twitch dystrophic muscles are the sites of terminal damage in muscular dystrophy Open
A striking pathological feature of dystrophinopathies is the presence of morphologically abnormal branched skeletal muscle fibers. The deterioration of muscle contractile function in Duchenne muscular dystrophy is accompanied by both an in…