Siraj Ahmed Khan
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View article: Evaluation of Serum Netrin-1 as a Novel Biomarker for Type 2 Diabetes Mellitus: A Cross-sectional Study
Evaluation of Serum Netrin-1 as a Novel Biomarker for Type 2 Diabetes Mellitus: A Cross-sectional Study Open
Background: Netrin-1, a protein known for its anti-inflammatory, tissue-regenerative, and immune-modulatory effects, has been shown to play a role in various biological processes. While inflammation is a key factor in the onset of insulin …
View article: Drug Usability Survey (DUS) of Gabapentinoid and Its Combinations Among Indian Patients With Neuropathic Pain: Results From a Real-World, Multicenter, Retrospective Survey at Neurology Clinics
Drug Usability Survey (DUS) of Gabapentinoid and Its Combinations Among Indian Patients With Neuropathic Pain: Results From a Real-World, Multicenter, Retrospective Survey at Neurology Clinics Open
Gabapentinoid-based treatments combined with TCA and SSNRI are useful and well-accepted treatment modalities by neurologists in painful neuropathies. Gabapentinoids are non-opioids with no risk of abuse and addiction and were considered th…
View article: Referee report. For: Determinants of urban mosquito population density and community responses: A cross-sectional study [version 1; peer review: 1 not approved]
Referee report. For: Determinants of urban mosquito population density and community responses: A cross-sectional study [version 1; peer review: 1 not approved] Open
View article: The Role of Salbutamol in the Management of Transient Tachypnea of the Newborn: A Systematic Review and Meta-Analysis
The Role of Salbutamol in the Management of Transient Tachypnea of the Newborn: A Systematic Review and Meta-Analysis Open
View article: Diagnostic utility of antibodies to structural protein and fibroblast intermediate filament, vimentin, in the detection of rheumatoid arthritis
Diagnostic utility of antibodies to structural protein and fibroblast intermediate filament, vimentin, in the detection of rheumatoid arthritis Open
Objectives: This study aimed to evaluate the specificity and sensitivity of serum anti-mutated citrullinated vimentin (MCV) antibodies in rheumatoid arthritis (RA) patients and to determine their diagnostic utility compared to anti-cyclic …
View article: Unveiling the Synergy of Serum Lipoprotein-Associated Phospholipase A2 and PLA2G7 Gene Polymorphism (rs1805017) as Key Determinants of Coronary Artery Disease Risk and Severity: Implications for Early Intervention
Unveiling the Synergy of Serum Lipoprotein-Associated Phospholipase A2 and PLA2G7 Gene Polymorphism (rs1805017) as Key Determinants of Coronary Artery Disease Risk and Severity: Implications for Early Intervention Open
Background Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a key enzyme selectively expressed in unstable, rupture-prone atherosclerotic plaques. Previous research has established a strong link between the PLA2G7 gene and the d…
View article: An Integrated Approach for Development of a Decision Support System for Early Surveillance of Japanese Encephalitis: a Remote Sensing-based study in Conjunction with Epidemiological Scenario in Assam, India
An Integrated Approach for Development of a Decision Support System for Early Surveillance of Japanese Encephalitis: a Remote Sensing-based study in Conjunction with Epidemiological Scenario in Assam, India Open
Japanese Encephalitis (JE) is one of the serious mosquito borne viral diseases mostly prevalent in India and many of the South Asian countries. A comprehensive study was conducted in Dibrugarh, a JE endemic district of Assam taking into th…
View article: Persistence of West Nile Virus circulation in northeast region of India: A prospective facility-based study spanning over a decade
Persistence of West Nile Virus circulation in northeast region of India: A prospective facility-based study spanning over a decade Open
Background & objectives: To understand the distribution and presence of West Nile (WN) among the acute encephalitis syndrome (AES) patients, a prospective facility-based study was conducted over a period of 13 years (2007-2019). Methods: D…
View article: Evaluation of Soluble P-selectin in Patients with Venous Thrombosis – An Observational Study
Evaluation of Soluble P-selectin in Patients with Venous Thrombosis – An Observational Study Open
Background: Venous thrombosis is a common life-threatening disorder and is a significant source of morbidity and mortality in hospitalized patients. This study aims to evaluate soluble P-selectin (sP-Sel) and to correlate with D-dimer and …
View article: Plasma Homocysteine Levels as Cardiovascular Disease Risk vis-a-vis Estrogen Levels in Pre and Postmenopausal Women
Plasma Homocysteine Levels as Cardiovascular Disease Risk vis-a-vis Estrogen Levels in Pre and Postmenopausal Women Open
Objectives: The objective of the study is to evaluate plasma homocysteine level and its relation with serum estrogen in pre and postmenopausal women as a risk factor in coronary artery disease (CAD). Materials and Methods: A cross-sectiona…
View article: Trends of Diagnostic Methods for Human Viral Diseases
Trends of Diagnostic Methods for Human Viral Diseases Open
The global health field is significantly affected by viral infections, and sero-diagnosis is crucial in diagnostic virology. Various laboratory techniques such as nucleic acid detection, viral culture, and antigen detection are essential f…
View article: Investigation of in vitro and in vivo therapeutic activity of Tarantula cubensis extract (Theranekron®) on Leishmania major
Investigation of in vitro and in vivo therapeutic activity of Tarantula cubensis extract (Theranekron®) on Leishmania major Open
Background & objectives: Cutaneous leishmaniasis (CL) is a vector-borne parasitic disease caused by several species of the protozoan parasite Leishmania. The need for new anti-leishmanial drugs for the treatment of CL is complicated by fac…
View article: Iron Deficiency and Hypoferritinaemia in Patients with Subclinical Hypothyroidism: A Retrospective Observational Study
Iron Deficiency and Hypoferritinaemia in Patients with Subclinical Hypothyroidism: A Retrospective Observational Study Open
Introduction: Iron acts as a cofactor in Thyroid Peroxidase (TPO) activity, and low iron levels can impact thyroid hormone metabolism. The function of ferritin and iron has been extensively documented in various studies in patients with Ov…
View article: Review of: "[Short Communication] Immunology of a Morbillivirus: Measles 1954 to 2023"
Review of: "[Short Communication] Immunology of a Morbillivirus: Measles 1954 to 2023" Open
Methodology, Results, and conclusion.So, authors should improvise it accordingly, as the abstract contains information only regarding to Background
View article: Estimating syphilis seroprevalence among patients in a sexually transmitted infections clinic in Lilongwe, Malawi
Estimating syphilis seroprevalence among patients in a sexually transmitted infections clinic in Lilongwe, Malawi Open
The syndromic management of genital ulcer disease (GUD) misses asymptomatic syphilis cases but is widely utilized in resource-limited settings without diagnostic capabilities to ensure treatment for the most common etiologies of GUD. We us…
View article: Editorial: One Health approaches to combat infectious diseases
Editorial: One Health approaches to combat infectious diseases Open
EDITORIAL article Front. Microbiol., 07 November 2023Sec. Infectious Agents and Disease Volume 14 - 2023 | https://doi.org/10.3389/fmicb.2023.1321134
View article: Malaria Vector Bionomics: Countrywide Surveillance Study on Implications for Malaria Elimination in India
Malaria Vector Bionomics: Countrywide Surveillance Study on Implications for Malaria Elimination in India Open
Background The biological characteristics of mosquito vectors vary, impacting their response to control measures. Thus, having up-to-date information on vector bionomics is essential to maintain the effectiveness of existing control strate…
View article: N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein and ferritin in predicting the functional outcome in stroke patients
N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein and ferritin in predicting the functional outcome in stroke patients Open
Background: Biomarkers that predict the outcome of stroke are critical for treatment, considering them to be a valuable adjunct to routine clinical examination and imaging data. Methods: Thirty-one patients admitted with stroke along with …
View article: A Study on the Bionomics of Primary Malaria Vectors Anopheles minimus and Anopheles baimaii in Some States of North East Region of India
A Study on the Bionomics of Primary Malaria Vectors Anopheles minimus and Anopheles baimaii in Some States of North East Region of India Open
Northeast region (NER) states of India remain highly malarious due to their geographical and ecotype diversity. Furthermore, rapid urbanization and change in climate are also affecting the vector biology and behavior of the existing specie…
View article: Clinical features and biochemical parameters influencing mortality in COVID-19 patients — Retrospective study from Telangana, India
Clinical features and biochemical parameters influencing mortality in COVID-19 patients — Retrospective study from Telangana, India Open
The coronavirus disease COVID-19 caused by SARS-CoV-2 was a worldwide public health emergency which affected millions of people including frontline healthcare workers too. We evaluated the clinical features and biochemical investigations i…
View article: Vaccination coverage and breakthrough infections of COVID-19 during the second wave among staff of selected medical institutions in India
Vaccination coverage and breakthrough infections of COVID-19 during the second wave among staff of selected medical institutions in India Open
India experienced the second wave of SARS-CoV-2 infection from April 3 to June 10, 2021. During the second wave, Delta variant B.1617.2 emerged as the predominant strain, spiking cases from 12.5 million to 29.3 million (cumulative) by the …
View article: Susceptibility status of Cx. vishnui subgroup of mosquitoes against different Insecticides and detection of novel mutations in esterase beta gene in Cx. tritaeniorhynchus
Susceptibility status of Cx. vishnui subgroup of mosquitoes against different Insecticides and detection of novel mutations in esterase beta gene in Cx. tritaeniorhynchus Open
Japanese encephalitis (JE) is a mosquito-borne viral disease and several species of the Culex genera can transmit JE. The present study was conducted to observe resistance in Cx. vishnui subgroup against organophosphates, widely used in fo…
View article: Clinical Utility of Pro-inflammatory Oligomeric Glycoprotein Tenascin-C in the Diagnosis of Seropositive and Seronegative Rheumatoid Arthritis
Clinical Utility of Pro-inflammatory Oligomeric Glycoprotein Tenascin-C in the Diagnosis of Seropositive and Seronegative Rheumatoid Arthritis Open
View article: Malaria Vector Bionomics: Countrywide Surveillance Study on Implications for Malaria Elimination in India (Preprint)
Malaria Vector Bionomics: Countrywide Surveillance Study on Implications for Malaria Elimination in India (Preprint) Open
BACKGROUND The biological characteristics of mosquito vectors vary, impacting their response to control measures. Thus, having up-to-date information on vector bionomics is essential to maintain the effectiveness of existing control strat…
View article: Evaluation of Serum Mammaglobin as an Alternative Biomarker in the Diagnosis of Breast Tumors
Evaluation of Serum Mammaglobin as an Alternative Biomarker in the Diagnosis of Breast Tumors Open
Introduction Breast cancer is the most common cancer in women in India and accounts for 14% of all cancers in women. Rise in mortality is due to lack of awareness and proper screening. Mammography and presently available serum biomarkers h…
View article: Molecular detection of Orientia tsutsugamushi strains circulating in Nagaland
Molecular detection of Orientia tsutsugamushi strains circulating in Nagaland Open
The antigenic heterogeneity of Orientia in India is still unknown in many disease endemic areas. The present study aims to characterize the strains of O. tsutsugamushi circulating in Nagaland, Northeast India. Two patients clinically diagn…
View article: Molecular Docking and in Vitro Anticancer Studies of Silver(I)-N-Heterocyclic Carbene Complexes
Molecular Docking and in Vitro Anticancer Studies of Silver(I)-N-Heterocyclic Carbene Complexes Open
View article: Seroprevalence of Dengue Infection Using IgG Capture ELISA in India, 2017–2018
Seroprevalence of Dengue Infection Using IgG Capture ELISA in India, 2017–2018 Open
We conducted a nationally representative population-based survey in 60 districts from 15 Indian states covering all five geographic regions during 2017–2018 to estimate the age specific seroprevalence of dengue. Of the 12,300 sera collecte…
View article: P-23 Experience of concurrent chemoradiotherapy for pancreatic cancer in a large university hospital
P-23 Experience of concurrent chemoradiotherapy for pancreatic cancer in a large university hospital Open
View article: Global emergence of West Nile virus
Global emergence of West Nile virus Open
West Nile virus (WNV) is a mosquito-borne single-stranded RNA neurotropic virus within the family Flaviviridae . The virus was first reported in the West Nile province of Uganda in 1937. Since then, sporadic cases have been reported until …